COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms M Ostaszewski, A Niarakis, A Mazein, I Kuperstein, R Phair, ... Molecular systems biology 17 (10), e10387, 2021 | 85 | 2021 |
Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection C Loucera, M Esteban-Medina, K Rian, MM Falco, J Dopazo, ... Signal transduction and targeted therapy 5 (1), 290, 2020 | 61 | 2020 |
Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients C Loucera, M Peña-Chilet, M Esteban-Medina, D Muñoyerro-Muñiz, ... Scientific reports 11 (1), 23380, 2021 | 41 | 2021 |
Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models M Esteban-Medina, M Peña-Chilet, C Loucera, J Dopazo BMC bioinformatics 20, 1-15, 2019 | 30 | 2019 |
Using mechanistic models for the clinical interpretation of complex genomic variation M Peña-Chilet, M Esteban-Medina, MM Falco, K Rian, MR Hidalgo, ... Scientific reports 9 (1), 18937, 2019 | 23 | 2019 |
Mechanistic modeling of the SARS-CoV-2 disease map K Rian, M Esteban-Medina, MR Hidalgo, C Çubuk, MM Falco, C Loucera, ... BioData mining 14, 1-8, 2021 | 22 | 2021 |
Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data K Rian, MR Hidalgo, C Çubuk, MM Falco, C Loucera, M Esteban-Medina, ... Computational and Structural Biotechnology Journal 19, 2968-2978, 2021 | 14 | 2021 |
An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice L Olivares-González, S Velasco, I Gallego, M Esteban-Medina, G Puras, ... Antioxidants 12 (1), 98, 2022 | 6 | 2022 |
Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell–Matrix Interactions P Puerto-Camacho, J Díaz-Martín, J Olmedo-Pelayo, A Bolado-Carrancio, ... International Journal of Molecular Sciences 23 (15), 8657, 2022 | 6 | 2022 |
Real world evidence of calcifediol use and mortality rate of COVID-19 hospitalized in a large cohort of 16,401 Andalusian patients C Loucera, M Peña-Chilet, M Esteban-Medina, D Muñoyerro-Muñiz, ... MedRxiv, 2021.04. 27.21255937, 2021 | 6 | 2021 |
Contributions from the 2019 literature on bioinformatics and translational informatics M Smaïl-Tabbone, B Rance Yearbook of Medical Informatics 29 (01), 188-192, 2020 | 4 | 2020 |
Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments C Loucera, R Carmona, M Esteban-Medina, G Bostelmann, ... Virology Journal 20 (1), 226, 2023 | 3 | 2023 |
Real-world evidence with a retrospective cohort of 15,968 Andalusian COVID-19 hospitalized patients suggests 21 new effective treatments and one drug that increases death risk C Loucera, R Carmona, M Esteban-Medina, G Bostelmann, ... medRxiv, 2022.08. 14.22278751, 2022 | 2 | 2022 |
A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanisms A Niarakis, M Ostaszewski, A Mazein, I Kuperstein, M Kutmon, ... bioRxiv, 2022.12. 17.520865, 2022 | 1 | 2022 |
drexml: A command line tool and Python package for drug repurposing M Esteban-Medina, VM de la Oliva Roque, S Herráiz-Gil, M Peña-Chilet, ... Computational and Structural Biotechnology Journal 23, 1129-1143, 2024 | | 2024 |
loucerac/drexml: v1. 1.1 C Loucera, M Esteban-Medina, VM Oliva Roque, S Herráiz-Gil Zenodo, 2024 | | 2024 |
Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches A Niarakis, M Ostaszewski, A Mazein, I Kuperstein, M Kutmon, ... Frontiers in Immunology 14, 1282859, 2024 | | 2024 |
Additional file 1 of The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery M Esteban-Medina, C Loucera, K Rian, S Velasco, L Olivares-González, ... Figshare, 2024 | | 2024 |
The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery M Esteban-Medina, C Loucera, K Rian, S Velasco, L Olivares-González, ... Journal of Translational Medicine 22 (1), 139, 2024 | | 2024 |
Leveraging machine learning and mechanistic models to accelerate therapeutic target discovery and drug repositioning M Esteban-Medina Universidad de Córdoba, UCOPress, 2024 | | 2024 |