How do protein kinases recognize their substrates? LA Pinna, M Ruzzene Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1314 (3), 191-225, 1996 | 635 | 1996 |
Selectivity of 4, 5, 6, 7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 (‘casein kinase-2’) S Sarno, H Reddy, F Meggio, M Ruzzene, SP Davies, A Donella-Deana, ... FEBS letters 496 (1), 44-48, 2001 | 424 | 2001 |
Addiction to protein kinase CK2: a common denominator of diverse cancer cells? M Ruzzene, LA Pinna Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 499-504, 2010 | 403 | 2010 |
Protein kinase CK2 phosphorylates and upregulates Akt/PKB G Di Maira, M Salvi, G Arrigoni, O Marin, S Sarno, F Brustolon, LA Pinna, ... Cell Death & Differentiation 12 (6), 668-677, 2005 | 396 | 2005 |
Different susceptibility of protein kinases to staurosporine inhibition: kinetic studies and molecular bases for the resistance of protein kinase CK2 F Meggio, AD Deana, M Ruzzene, AM Brunati, L Cesaro, B Guerra, ... European Journal of Biochemistry 234 (1), 317-322, 1995 | 355 | 1995 |
The selectivity of inhibitors of protein kinase CK2: an update MA Pagano, J Bain, Z Kazimierczuk, S Sarno, M Ruzzene, G Di Maira, ... Biochemical Journal 415 (3), 353-365, 2008 | 279 | 2008 |
Protein kinase CK2 inhibitor 4, 5, 6, 7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1 … M Ruzzene, D Penzo, LA Pinna Biochemical Journal 364 (1), 41-47, 2002 | 272 | 2002 |
Salicylic acid activates nitric oxide synthesis in Arabidopsis M Zottini, A Costa, R De Michele, M Ruzzene, F Carimi, F Lo Schiavo Journal of Experimental Botany 58 (6), 1397-1405, 2007 | 226 | 2007 |
Optimization of protein kinase CK2 inhibitors derived from 4, 5, 6, 7-tetrabromobenzimidazole MA Pagano, M Andrzejewska, M Ruzzene, S Sarno, L Cesaro, J Bain, ... Journal of medicinal chemistry 47 (25), 6239-6247, 2004 | 222 | 2004 |
2-Dimethylamino-4, 5, 6, 7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2 MA Pagano, F Meggio, M Ruzzene, M Andrzejewska, Z Kazimierczuk, ... Biochemical and biophysical research communications 321 (4), 1040-1044, 2004 | 221 | 2004 |
Protein kinase CK2: a potential therapeutic target for diverse human diseases C Borgo, C D’Amore, S Sarno, M Salvi, M Ruzzene Signal transduction and targeted therapy 6 (1), 183, 2021 | 194 | 2021 |
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 G Cozza, M Mazzorana, E Papinutto, J Bain, M Elliott, G Di Maira, ... Biochemical Journal 421 (3), 387-395, 2009 | 186 | 2009 |
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5, 6-dihydroindolo-(1, 2-a) quinazolin-7-yl] acetic acid (IQA) S Sarno, E de Moliner, M Ruzzene, MA Pagano, R Battistutta, J Bain, ... Biochemical journal 374 (3), 639-646, 2003 | 170 | 2003 |
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: effect on schizophrenia susceptibility S Sacchi, M Bernasconi, M Martineau, JP Mothet, M Ruzzene, MS Pilone, ... Journal of biological chemistry 283 (32), 22244-22256, 2008 | 157 | 2008 |
Multiple myeloma cell survival relies on high activity of protein kinase CK2 FA Piazza, M Ruzzene, C Gurrieri, B Montini, L Bonanni, G Chioetto, ... Blood 108 (5), 1698-1707, 2006 | 148 | 2006 |
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors MA Pagano, G Poletto, G Di Maira, G Cozza, M Ruzzene, S Sarno, J Bain, ... Chembiochem 8 (1), 129-139, 2007 | 139 | 2007 |
Casein kinase: the triple meaning of a misnomer A Venerando, M Ruzzene, LA Pinna Biochemical Journal 460 (2), 141-156, 2014 | 136 | 2014 |
Protein kinase CK2 in hematologic malignancies: reliance on a pivotal cell survival regulator by oncogenic signaling pathways F Piazza, S Manni, M Ruzzene, LA Pinna, C Gurrieri, G Semenzato Leukemia 26 (6), 1174-1179, 2012 | 130 | 2012 |
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study F Meggio, MA Pagano, S Moro, G Zagotto, M Ruzzene, S Sarno, G Cozza, ... Biochemistry 43 (40), 12931-12936, 2004 | 115 | 2004 |
Development and exploitation of CK2 inhibitors S Sarno, M Ruzzene, P Frascella, MA Pagano, F Meggio, A Zambon, ... Molecular and cellular biochemistry 274, 69-76, 2005 | 110 | 2005 |