Identification of the Hepatocyte Growth Factor Receptor As the c-met Proto-Oncogene Product DP Bottaro, JS Rubin, DL Faletto, AML Chan, TE Kmiecik, ... science 251 (4995), 802-804, 1991 | 2995 | 1991 |
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma TCGAR Network The New England Journal of Medicine 374, 135-145, 2016 | 1196 | 2016 |
Activation of RET as a Dominant Transforming Gene by Germline Mutations of MEN2A and MEN2B M Santoro, F Carlomagno, A Romano, DP Bottaro, NA Dathan, M Grieco, ... Science 267 (5196), 381-383, 1995 | 1013 | 1995 |
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. T Miki, DP Bottaro, TP Fleming, CL Smith, WH Burgess, AM Chan, ... Proceedings of the National Academy of Sciences 89 (1), 246-250, 1992 | 962 | 1992 |
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ... Cell reports 23 (1), 313-326. e5, 2018 | 837 | 2018 |
A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. JS Rubin, AML Chan, DP Bottaro, WH Burgess, WG Taylor, AC Cech, ... Proceedings of the National Academy of Sciences 88 (2), 415-419, 1991 | 639 | 1991 |
PDGF induction of tyrosine phosphorylation of GTPase activating protein CJ Molloy, DP Bottaro, TP Fleming, MS Marshall, JB Gibbs, SA Aaronson Nature 342 (6250), 711-714, 1989 | 556 | 1989 |
Targeting the c-Met signaling pathway in cancer B Peruzzi, DP Bottaro Clinical cancer research 12 (12), 3657-3660, 2006 | 555 | 2006 |
Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop T Miki, TP Fleming, DP Bottaro, JS Rubin, D Ron, SA Aaronson Science 251 (4989), 72-75, 1991 | 543 | 1991 |
Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling A Uren, F Reichsman, V Anest, WG Taylor, K Muraiso, DP Bottaro, ... Journal of Biological Chemistry 275 (6), 4374-4382, 2000 | 503 | 2000 |
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma TK Choueiri, U Vaishampayan, JE Rosenberg, TF Logan, AL Harzstark, ... Journal of Clinical Oncology 31 (2), 181-186, 2013 | 488 | 2013 |
Keratinocyte growth factor JS Rubin, DP Bottaro, M Chedid, T Miki, D Ron, HG Cheon, WG Taylor, ... Cell biology international 19 (5), 399-412, 1995 | 396 | 1995 |
Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling P Fedi, A Bafico, AN Soria, WH Burgess, T Miki, DP Bottaro, MH Kraus, ... Journal of biological Chemistry 274 (27), 19465-19472, 1999 | 385 | 1999 |
Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product JS Rubin, DP Bottaro, SA Aaronson Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1155 (3), 357-371, 1993 | 368 | 1993 |
Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases MP De Caestecker, WT Parks, CJ Frank, P Castagnino, DP Bottaro, ... Genes & development 12 (11), 1587-1592, 1998 | 364 | 1998 |
Multilevel genomics-based taxonomy of renal cell carcinoma F Chen, Y Zhang, Y Şenbabaoğlu, G Ciriello, L Yang, E Reznik, B Shuch, ... Cell reports 14 (10), 2476-2489, 2016 | 346 | 2016 |
c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype T Otsuka, H Takayama, R Sharp, G Celli, WJ LaRochelle, DP Bottaro, ... Cancer research 58 (22), 5157-5167, 1998 | 333 | 1998 |
Genetic basis of cancer of the kidney: disease-specific approaches to therapy WM Linehan, J Vasselli, R Srinivasan, MCM Walther, M Merino, P Choyke, ... Clinical Cancer Research 10 (18), 6282S-6289S, 2004 | 297 | 2004 |
Identification of a competitive HGF antagonist encoded by an alternative transcript AML Chan, JS Rubin, DP Bottaro, DW Hirschfield, M Chedid, ... Science 254 (5036), 1382-1385, 1991 | 285 | 1991 |
Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers EC Kauffman, CJ Ricketts, S Rais-Bahrami, Y Yang, MJ Merino, ... Nature Reviews Urology 11 (8), 465-475, 2014 | 282 | 2014 |