Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy JT Hinson, A Chopra, N Nafissi, WJ Polacheck, CC Benson, S Swist, ... Science 349 (6251), 982-986, 2015 | 645 | 2015 |
Myosin sequestration regulates sarcomere function, cardiomyocyte energetics, and metabolism, informing the pathogenesis of hypertrophic cardiomyopathy CN Toepfer, AC Garfinkel, G Venturini, H Wakimoto, G Repetti, L Alamo, ... Circulation 141 (10), 828-842, 2020 | 247 | 2020 |
Transfer learning enables predictions in network biology CV Theodoris, L Xiao, A Chopra, MD Chaffin, ZR Al Sayed, MC Hill, ... Nature 618 (7965), 616-624, 2023 | 224 | 2023 |
Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing A Chopra, E Tabdanov, H Patel, PA Janmey, JY Kresh American Journal of Physiology-Heart and Circulatory Physiology 300 (4 …, 2011 | 177 | 2011 |
Force generation via β-cardiac myosin, titin, and α-actinin drives cardiac sarcomere assembly from cell-matrix adhesions A Chopra, ML Kutys, K Zhang, WJ Polacheck, CC Sheng, RJ Luu, ... Developmental cell 44 (1), 87-96. e5, 2018 | 152 | 2018 |
Augmentation of integrin-mediated mechanotransduction by hyaluronic acid A Chopra, ME Murray, FJ Byfield, MG Mendez, R Halleluyan, DJ Restle, ... Biomaterials 35 (1), 71-82, 2014 | 135 | 2014 |
Intercellular and extracellular mechanotransduction in cardiac myocytes JY Kresh, A Chopra Pflügers Archiv-European Journal of Physiology 462, 75-87, 2011 | 108 | 2011 |
SarcTrack: an adaptable software tool for efficient large-scale analysis of sarcomere function in hiPSC-cardiomyocytes CN Toepfer, A Sharma, M Cicconet, AC Garfinkel, M Mücke, M Neyazi, ... Circulation research 124 (8), 1172-1183, 2019 | 106 | 2019 |
Integrative analysis of PRKAG2 cardiomyopathy iPS and microtissue models identifies AMPK as a regulator of metabolism, survival, and fibrosis JT Hinson, A Chopra, A Lowe, CC Sheng, RM Gupta, R Kuppusamy, ... Cell reports 17 (12), 3292-3304, 2016 | 98 | 2016 |
Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors A Chopra, V Lin, A McCollough, S Atzet, GD Prestwich, AS Wechsler, ... Journal of biomechanics 45 (5), 824-831, 2012 | 93 | 2012 |
Proteomic analysis of human pluripotent stem Cell–Derived, fetal, and adult ventricular cardiomyocytes reveals pathways crucial for cardiac metabolism and maturation E Poon, W Keung, Y Liang, R Ramalingam, B Yan, S Zhang, A Chopra, ... Circulation: Cardiovascular Genetics 8 (3), 427-436, 2015 | 60 | 2015 |
Phospholamban as a Crucial Determinant of the Inotropic Response of Human Pluripotent Stem Cell–Derived Ventricular Cardiomyocytes and Engineered 3-Dimensional Tissue Constructs G Chen, S Li, I Karakikes, L Ren, M Zi-Ying Chow, A Chopra, W Keung, ... Circulation: Arrhythmia and Electrophysiology 8 (1), 193-202, 2015 | 47 | 2015 |
Filamin C cardiomyopathy variants cause protein and lysosome accumulation R Agarwal, JA Paulo, CN Toepfer, JK Ewoldt, S Sundaram, A Chopra, ... Circulation research 129 (7), 751-766, 2021 | 38 | 2021 |
α-Catenin localization and sarcomere self-organization on N-cadherin adhesive patterns are myocyte contractility driven A Chopra, A Patel, AC Shieh, P A. Janmey, JY Kresh Public Library of Science 7 (10), e47592, 2012 | 21 | 2012 |
Force measurement tools to explore cadherin mechanotransduction SC Stapleton, A Chopra, CS Chen Cell communication & adhesion 21 (3), 193-205, 2014 | 17 | 2014 |
Non-cell autonomous cues for enhanced functionality of human embryonic stem cell-derived cardiomyocytes via maturation of sarcolemmal and mitochondrial KATP channels W Keung, L Ren, S Li, AOT Wong, A Chopra, CW Kong, GF Tomaselli, ... Scientific reports 6 (1), 34154, 2016 | 13 | 2016 |
Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue J Javor, JK Ewoldt, PE Cloonan, A Chopra, RJ Luu, G Freychet, ... Microsystems & Nanoengineering 7 (1), 10, 2021 | 10 | 2021 |
Substrate elasticity as a probe to measure mechanosensing at cell-cell and cell-matrix junctions JP Winer, A Chopra, JY Kresh, PA Janmey Mechanobiology of cell-cell and cell-matrix interactions, 11-22, 2011 | 10 | 2011 |
Switching a HO··· π Interaction to a Nonconventional OH··· π Hydrogen Bond: A Completed Crystallographic Puzzle M Kazim, L Guan, A Chopra, R Sun, MA Siegler, T Lectka The Journal of Organic Chemistry 85 (15), 9801-9807, 2020 | 9 | 2020 |
Sarco/endoplasmic reticulum Ca2+-ATPase is a more effective calcium remover than sodium-calcium exchanger in human embryonic stem cell-derived … S Li, A Chopra, W Keung, CWY Chan, KD Costa, CW Kong, RJ Hajjar, ... American Journal of Physiology-Heart and Circulatory Physiology 317 (5 …, 2019 | 9 | 2019 |