Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression Y Tan, A Tajik, J Chen, Q Jia, F Chowdhury, L Wang, J Chen, S Zhang, ... Nature communications 5 (1), 4619, 2014 | 195 | 2014 |
Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins J Seong, A Tajik, J Sun, JL Guan, MJ Humphries, SE Craig, A Shekaran, ... Proceedings of the National Academy of Sciences 110 (48), 19372-19377, 2013 | 195 | 2013 |
Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells TJ Kim, J Seong, M Ouyang, J Sun, S Lu, JP Hong, N Wang, Y Wang Journal of cellular physiology 218 (2), 285-293, 2009 | 172 | 2009 |
Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer J Seong, M Ouyang, T Kim, J Sun, PC Wen, S Lu, Y Zhuo, NM Llewellyn, ... Nature communications 2 (1), 406, 2011 | 143 | 2011 |
Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs TJ Kim, C Joo, J Seong, R Vafabakhsh, EL Botvinick, MW Berns, ... Elife 4, e04876, 2015 | 105 | 2015 |
Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging M Ouyang, S Lu, XY Li, J Xu, J Seong, BNG Giepmans, JYJ Shyy, ... Journal of Biological Chemistry 283 (25), 17740-17748, 2008 | 98 | 2008 |
Mechanotransduction at focal adhesions: from physiology to cancer development J Seong, N Wang, Y Wang Journal of cellular and molecular medicine 17 (5), 597-604, 2013 | 87 | 2013 |
Activation of RIG-I-mediated antiviral signaling triggers autophagy through the MAVS-TRAF6-Beclin-1 signaling axis NR Lee, J Ban, NJ Lee, CM Yi, JY Choi, H Kim, JK Lee, J Seong, NH Cho, ... Frontiers in immunology 9, 2096, 2018 | 84 | 2018 |
Visualization of Src activity at different compartments of the plasma membrane by FRET imaging J Seong, S Lu, M Ouyang, H Huang, J Zhang, MC Frame, Y Wang Chemistry & biology 16 (1), 48-57, 2009 | 83 | 2009 |
N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways M Ouyang, S Lu, T Kim, CE Chen, J Seong, DE Leckband, F Wang, ... Nature communications 4 (1), 1589, 2013 | 67 | 2013 |
The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging S Lu, M Ouyang, J Seong, J Zhang, S Chien, Y Wang PLoS computational biology 4 (7), e1000127, 2008 | 64 | 2008 |
Single molecular force across single integrins dictates cell spreading F Chowdhury, ITS Li, BJ Leslie, S Doğanay, R Singh, X Wang, J Seong, ... Integrative Biology 7 (10), 1265-1271, 2015 | 50 | 2015 |
Polyethylenimine‐based antisense oligodeoxynucleotides of IL‐4 suppress the production of IL‐4 in a murine model of airway inflammation JH Seong, KM Lee, ST Kim, SE Jin, CK Kim The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2006 | 44 | 2006 |
Genetically encoded biosensors based on fluorescent proteins H Kim, J Ju, HN Lee, H Chun, J Seong Sensors 21 (3), 795, 2021 | 43 | 2021 |
Optobiochemistry: genetically encoded control of protein activity by light J Seong, MZ Lin Annual Review of Biochemistry 90 (1), 475-501, 2021 | 34 | 2021 |
Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions J Sun, L Lei, CM Tsai, Y Wang, Y Shi, M Ouyang, S Lu, J Seong, TJ Kim, ... Nature communications 8 (1), 477, 2017 | 32 | 2017 |
In-situ coupling between kinase activities and protein dynamics within single focal adhesions Y Wu, K Zhang, J Seong, J Fan, S Chien, Y Wang, S Lu Scientific reports 6 (1), 29377, 2016 | 27 | 2016 |
Computational analysis of the spatiotemporal coordination of polarized PI3K and Rac1 activities in micro-patterned live cells S Lu, T Kim, CE Chen, M Ouyang, J Seong, X Liao, Y Wang PloS one 6 (6), e21293, 2011 | 26 | 2011 |
Live cell imaging of Src/FAK signaling by FRET J Seong, S Lu, Y Wang Cellular and molecular bioengineering 4, 138-147, 2011 | 26 | 2011 |
RhoA GTPase phosphorylated at tyrosine 42 by src kinase binds to β-catenin and contributes transcriptional regulation of vimentin upon Wnt3A JG Kim, S Mahmud, JK Min, YB Lee, H Kim, DC Kang, HS Park, J Seong, ... Redox Biology 40, 101842, 2021 | 25 | 2021 |