Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease M Zarei, E Barroso, X Palomer, J Dai, P Rada, T Quesada-López, ... Molecular metabolism 8, 117-131, 2018 | 100 | 2018 |
Chemistry of pyramidalized alkenes S Vázquez, P Camps Tetrahedron 61 (22), 5147-5208, 2005 | 100 | 2005 |
Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus MD Duque, C Ma, E Torres, J Wang, L Naesens, J Juárez-Jiménez, ... Journal of medicinal chemistry 54 (8), 2646-2657, 2011 | 87 | 2011 |
Pharmacological inhibition of soluble epoxide hydrolase as a new therapy for Alzheimer’s Disease C Griñán-Ferré, S Codony, E Pujol, J Yang, R Leiva, C Escolano, ... bioRxiv, 605055, 2019 | 66 | 2019 |
Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus M Rey-Carrizo, M Barniol-Xicota, C Ma, M Frigolé-Vivas, E Torres, ... Journal of medicinal chemistry 57 (13), 5738-5747, 2014 | 63 | 2014 |
Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse model C Griñán-Ferré, L Marsal-García, A Bellver-Sanchis, SM Kondengaden, ... Aging (Albany NY) 11 (23), 11591, 2019 | 61 | 2019 |
3-Azatetracyclo[5.2.1.15,8.01,5]undecane Derivatives: From Wild-Type Inhibitors of the M2 Ion Channel of Influenza A Virus to Derivatives with Potent Activity … M Rey-Carrizo, E Torres, C Ma, M Barniol-Xicota, J Wang, Y Wu, ... Journal of medicinal chemistry 56 (22), 9265-9274, 2013 | 55 | 2013 |
A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice J Companys-Alemany, AL Turcu, A Bellver-Sanchis, MI Loza, JM Brea, ... Pharmaceutics 12 (3), 284, 2020 | 53 | 2020 |
Synthesis, Chemical Trapping, and Dimerization of 3,7‐Dimethyltricyclo[3.3.0.03, 7]oct‐1(5)‐ene: [2 + 2] Retrocycloaddition of the Cyclobutane Dimer P Camps, F Pérez, S Vázquez, M Font‐Bardia, X Solans Angewandte Chemie International Edition in English 34 (8), 912-914, 1995 | 52 | 1995 |
Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs P Camps, MD Duque, S Vázquez, L Naesens, E De Clercq, FX Sureda, ... Bioorganic & medicinal chemistry 16 (23), 9925-9936, 2008 | 51 | 2008 |
Synthesis, chemical trapping and dimerization of tricyclo [3.3. 0.03, 7] oct-1 (5)-ene, the consummate member of a series of pyramidalized alkenes P Camps, FJ Luque, M Orozco, F Pérez, S Vázquez Tetrahedron letters 37 (47), 8605-8608, 1996 | 46 | 1996 |
Synthesis and anti-influenza A virus activity of 2, 2-dialkylamantadines and related compounds E Torres, R Fernández, S Miquet, M Font-Bardia, E Vanderlinden, ... ACS medicinal chemistry letters 3 (12), 1065-1069, 2012 | 43 | 2012 |
Heme-regulated eIF2α kinase modulates hepatic FGF21 and is activated by PPARβ/δ deficiency M Zarei, E Barroso, R Leiva, M Barniol-Xicota, E Pujol, C Escolano, ... Diabetes 65 (10), 3185-3199, 2016 | 42 | 2016 |
Highly pyramidalized tricyclo [3.3. 0.03, 7] oct-1 (5)-ene and related compounds: High-level ab initio study, synthesis and trapping of tetracyclo [5.2. 1.02, 6.03, 8] dec-7 … P Camps, M Font-Bardia, N Méndez, F Pérez, X Pujol, X Solans, ... Tetrahedron 54 (18), 4679-4696, 1998 | 42 | 1998 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors FJ Pérez-Areales, AL Turcu, M Barniol-Xicota, C Pont, D Pivetta, ... European journal of medicinal chemistry 180, 613-626, 2019 | 41 | 2019 |
Aniline-based inhibitors of influenza H1N1 virus acting on hemagglutinin-mediated fusion R Leiva, M Barniol-Xicota, S Codony, T Ginex, E Vanderlinden, M Montes, ... Journal of Medicinal Chemistry 61 (1), 98-118, 2018 | 41 | 2018 |
A concise approach to the preparation of 2-hydroxydiarylketones by an intramolecular acyl radical ipso substitution WB Motherwell, S Vázquez Tetrahedron Letters 41 (49), 9667-9671, 2000 | 40 | 2000 |
Hunsdiecker-Type Bromodecarboxylation of Carboxylic Acids with Iodosobenzene Diacetate–Bromine P Camps, AE Lukach, X Pujol, S Vázquez Tetrahedron 56 (17), 2703-2707, 2000 | 40 | 2000 |
Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl) amines MD Duque, P Camps, L Profire, S Montaner, S Vázquez, FX Sureda, ... Bioorganic & medicinal chemistry 17 (8), 3198-3206, 2009 | 38 | 2009 |
Observations on the enforced orthogonality concept for the synthesis of fully hindered biaryls by a tin-free intramolecular radical ipso substitution E Bonfand, L Forslund, WB Motherwell, S Vazquez Synlett 2000 (04), 475-478, 2000 | 38 | 2000 |