Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit M Rosas-Ballina, PS Olofsson, M Ochani, SI Valdés-Ferrer, YA Levine, ... Science 334 (6052), 98-101, 2011 | 1491 | 2011 |
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release H Yang, HS Hreggvidsdottir, K Palmblad, H Wang, M Ochani, J Li, B Lu, ... Proceedings of the National Academy of Sciences 107 (26), 11942-11947, 2010 | 937 | 2010 |
Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis FA Koopman, SS Chavan, S Miljko, S Grazio, S Sokolovic, PR Schuurman, ... Proceedings of the National Academy of Sciences 113 (29), 8284-8289, 2016 | 932 | 2016 |
Novel role of PKR in inflammasome activation and HMGB1 release B Lu, T Nakamura, K Inouye, J Li, Y Tang, P Lundbäck, SI Valdes-Ferrer, ... Nature 488 (7413), 670-674, 2012 | 838 | 2012 |
Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia M Rosas-Ballina, M Ochani, WR Parrish, K Ochani, YT Harris, JM Huston, ... Proceedings of the National Academy of Sciences 105 (31), 11008-11013, 2008 | 766 | 2008 |
Mechanisms and Therapeutic Relevance of Neuro-immune Communication. TKJ Chavan Sangeeta S, Pavlov VA Immunity 46, 927-942, 2017 | 566 | 2017 |
Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway VA Pavlov, WR Parrish, M Rosas-Ballina, M Ochani, M Puerta, K Ochani, ... Brain, behavior, and immunity 23 (1), 41-45, 2009 | 512 | 2009 |
Molecular and functional neuroscience in immunity VA Pavlov, SS Chavan, KJ Tracey Annual review of immunology 36 (1), 783-812, 2018 | 410 | 2018 |
Modulation of TNF release by choline requires α7 subunit nicotinic acetylcholine receptor-mediated signaling WR Parrish, M Rosas-Ballina, M Gallowitsch-Puerta, M Ochani, K Ochani, ... Molecular medicine 14, 567-574, 2008 | 403 | 2008 |
JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation B Lu, DJ Antoine, K Kwan, P Lundbäck, H Wähämaa, H Schierbeck, ... Proceedings of the National Academy of Sciences 111 (8), 3068-3073, 2014 | 381 | 2014 |
The microbiota regulate neuronal function and fear extinction learning C Chu, MH Murdock, D Jing, TH Won, H Chung, AM Kressel, T Tsaava, ... Nature 574 (7779), 543-548, 2019 | 377 | 2019 |
MD-2 is required for disulfide HMGB1–dependent TLR4 signaling H Yang, H Wang, Z Ju, AA Ragab, P Lundbäck, W Long, SI Valdes-Ferrer, ... Journal of Experimental Medicine 212 (1), 5-14, 2015 | 373 | 2015 |
Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis JM Huston, M Gallowitsch-Puerta, M Ochani, K Ochani, R Yuan, ... Critical care medicine 35 (12), 2762-2768, 2007 | 373 | 2007 |
High mobility group box protein 1 (HMGB1): the prototypical endogenous danger molecule H Yang, H Wang, SS Chavan, U Andersson Molecular medicine 21, S6-S12, 2015 | 362 | 2015 |
The selective α7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE M Rosas-Ballina, RS Goldstein, M Gallowitsch-Puerta, L Yang, ... Molecular Medicine 15, 195-202, 2009 | 238 | 2009 |
Cholinergic anti-inflammatory pathway activity and High Mobility Group Box-1 (HMGB1) serum levels in patients with rheumatoid arthritis RS Goldstein, A Bruchfeld, L Yang, AR Qureshi, M Gallowitsch-Puerta, ... Molecular medicine 13, 210-215, 2007 | 237 | 2007 |
HMGB1 mediates cognitive impairment in sepsis survivors SS Chavan, PT Huerta, S Robbiati, SI Valdes-Ferrer, M Ochani, ... Molecular medicine 18, 930-937, 2012 | 225 | 2012 |
α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release B Lu, K Kwan, YA Levine, PS Olofsson, H Yang, J Li, S Joshi, H Wang, ... Molecular medicine 20, 350-358, 2014 | 207 | 2014 |
Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity TP Zanos, HA Silverman, T Levy, T Tsaava, E Battinelli, PW Lorraine, ... Proceedings of the National Academy of Sciences 115 (21), E4843-E4852, 2018 | 181 | 2018 |
α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex PS Olofsson, DA Katz, M Rosas-Ballina, YA Levine, M Ochani, ... Molecular medicine 18, 539-543, 2012 | 167 | 2012 |