Age-related clonal hematopoiesis associated with adverse outcomes S Jaiswal, P Fontanillas, J Flannick, A Manning, PV Grauman, BG Mar, ... New England Journal of Medicine 371 (26), 2488-2498, 2014 | 4449 | 2014 |
Acute myeloid leukemia ontogeny is defined by distinct somatic mutations RC Lindsley, BG Mar, E Mazzola, PV Grauman, S Shareef, SL Allen, ... Blood, The Journal of the American Society of Hematology 125 (9), 1367-1376, 2015 | 1012 | 2015 |
Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation RC Lindsley, W Saber, BG Mar, R Redd, T Wang, MD Haagenson, ... New England Journal of Medicine 376 (6), 536-547, 2017 | 720 | 2017 |
Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation R Bejar, KE Stevenson, B Caughey, RC Lindsley, BG Mar, P Stojanov, ... Journal of clinical oncology 32 (25), 2691-2698, 2014 | 467 | 2014 |
Clonal hematopoiesis associated with adverse outcomes after autologous stem-cell transplantation for lymphoma CJ Gibson, RC Lindsley, V Tchekmedyian, BG Mar, J Shi, S Jaiswal, ... Journal of Clinical Oncology 35 (14), 1598-1605, 2017 | 420 | 2017 |
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia S Buonamici, T Trimarchi, MG Ruocco, L Reavie, S Cathelin, BG Mar, ... Nature 459 (7249), 1000-1004, 2009 | 300 | 2009 |
Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia BG Mar, LB Bullinger, KM McLean, PV Grauman, MH Harris, K Stevenson, ... Nature communications 5 (1), 3469, 2014 | 207 | 2014 |
PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells JD Kahn, PG Miller, AJ Silver, RS Sellar, S Bhatt, C Gibson, M McConkey, ... Blood, The Journal of the American Society of Hematology 132 (11), 1095-1105, 2018 | 193 | 2018 |
SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia BG Mar, SH Chu, JD Kahn, AV Krivtsov, R Koche, CA Castellano, ... Blood, The Journal of the American Society of Hematology 130 (24), 2631-2641, 2017 | 125 | 2017 |
Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with TP53 mutations R Ajore, D Raiser, M McConkey, M Jöud, B Boidol, B Mar, G Saksena, ... EMBO molecular medicine 9 (4), 498-507, 2017 | 111 | 2017 |
Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial J Gotlib, A Reiter, DH Radia, MW Deininger, TI George, J Panse, ... Nature medicine 27 (12), 2192-2199, 2021 | 105 | 2021 |
Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial DJ DeAngelo, DH Radia, TI George, WA Robinson, AT Quiery, ... Nature medicine 27 (12), 2183-2191, 2021 | 104 | 2021 |
A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31 Z Hu, I Gomes, SK Horrigan, J Kravarusic, B Mar, Z Arbieva, B Chyna, ... Oncogene 20 (47), 6946-6954, 2001 | 99 | 2001 |
Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia BG Mar, L Bullinger, E Basu, K Schlis, LB Silverman, K Döhner, ... Leukemia 26 (8), 1881-1883, 2012 | 88 | 2012 |
The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia H Li, BG Mar, H Zhang, RV Puram, F Vazquez, BA Weir, WC Hahn, ... Blood, the Journal of the American Society of Hematology 129 (4), 497-508, 2017 | 75 | 2017 |
The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis BG Mar, D Amakye, I Aifantis, S Buonamici Leukemia 25 (11), 1665-1673, 2011 | 72 | 2011 |
The relative utilities of genome-wide, gene panel, and individual gene sequencing in clinical practice FC Kuo, BG Mar, RC Lindsley, NI Lindeman Blood, The Journal of the American Society of Hematology 130 (4), 433-439, 2017 | 65 | 2017 |
Self-renewal related signaling in myeloid leukemia stem cells FH Heidel, BG Mar, SA Armstrong International journal of hematology 94, 109-117, 2011 | 56 | 2011 |
Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia PD Bhola, BG Mar, RC Lindsley, JA Ryan, LJ Hogdal, TT Vo, ... The Journal of clinical investigation 126 (10), 3827-3836, 2016 | 45 | 2016 |
Novel transcription factors in human CD34 antigen–positive hematopoietic cells I Gomes, TT Sharma, S Edassery, N Fulton, BG Mar, CA Westbrook Blood, The Journal of the American Society of Hematology 100 (1), 107-119, 2002 | 36 | 2002 |