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Michelle Garrett
Michelle Garrett
Professor of Cancer Therapeutics
在 kent.ac.uk 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
New functional activities for the p21 family of CDK inhibitors.
J LaBaer, MD Garrett, LF Stevenson, JM Slingerland, C Sandhu, HS Chou, ...
Genes & development 11 (7), 847-862, 1997
18221997
Microinjection of recombinant p21rho induces rapid changes in cell morphology.
HF Paterson, AJ Self, MD Garrett, I Just, K Aktories, A Hall
The Journal of cell biology 111 (3), 1001-1007, 1990
9161990
Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises
TA Yap, MD Garrett, MI Walton, F Raynaud, JS de Bono, P Workman
Current opinion in pharmacology 8 (4), 393-412, 2008
6682008
Bcr encodes a GTPase-activating protein for p21rac
D Diekmann, S Brill, MD Garrett, N Totty, J Hsuan, C Monfries, C Hall, ...
Nature 351 (6325), 400-402, 1991
6531991
First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors
TA Yap, LI Yan, A Patnaik, I Fearen, D Olmos, K Papadopoulos, RD Baird, ...
Journal of clinical oncology 29 (35), 4688-4695, 2011
6222011
The ZO-1–associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
MS Balda, MD Garrett, K Matter
The Journal of cell biology 160 (3), 423-432, 2003
4982003
Cell cycle–regulated phosphorylation of p220NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription
T Ma, BA Van Tine, Y Wei, MD Garrett, D Nelson, PD Adams, J Wang, ...
Genes & development 14 (18), 2298-2313, 2000
4212000
CHK2 kinase: cancer susceptibility and cancer therapy–two sides of the same coin?
L Antoni, N Sodha, I Collins, MD Garrett
Nature Reviews Cancer 7 (12), 925-936, 2007
3552007
Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors
I Collins, MD Garrett
Current opinion in pharmacology 5 (4), 366-373, 2005
2962005
Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins
MD Garrett, AJ Self, C van Oers, A Hall
Journal of Biological Chemistry 264 (1), 10-13, 1989
2871989
The Cyclin-dependent Kinase Inhibitor CYC202 (R-Roscovitine) Inhibits Retinoblastoma Protein Phosphorylation, Causes Loss of Cyclin D1, and Activates the …
SR Whittaker, MI Walton, MD Garrett, P Workman
Cancer research 64 (1), 262-272, 2004
2562004
GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway.
MD Garrett, JE Zahner, CM Cheney, PJ Novick
The EMBO journal 13 (7), 1718-1728, 1994
2531994
Anticancer therapy with checkpoint inhibitors: what, where and when?
MD Garrett, I Collins
Trends in pharmacological sciences 32 (5), 308-316, 2011
2392011
Pyrido[2,3-d]pyrimidin-7-one Inhibitors of Cyclin-Dependent Kinases
M Barvian, DH Boschelli, J Cossrow, E Dobrusin, A Fattaey, A Fritsch, ...
Journal of medicinal chemistry 43 (24), 4606-4616, 2000
2262000
Biomarker-driven early clinical trials in oncology: a paradigm shift in drug development
DSW Tan, GV Thomas, MD Garrett, U Banerji, JS De Bono, SB Kaye, ...
The Cancer Journal 15 (5), 406-420, 2009
2152009
Regulation of NF‐κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
S Rocha, MD Garrett, KJ Campbell, K Schumm, ND Perkins
The EMBO journal 24 (6), 1157-1169, 2005
2122005
Discovering novel chemotherapeutic drugs for the third millennium
MD Garrett, P Workman
European Journal of Cancer 35 (14), 2010-2030, 1999
1971999
CDK inhibition and cancer therapy
MD Garrett, A Fattaey
Current opinion in genetics & development 9 (1), 104-111, 1999
1971999
Identification of inhibitors of protein kinase B using fragment-based lead discovery
G Saxty, SJ Woodhead, V Berdini, TG Davies, ML Verdonk, PG Wyatt, ...
Journal of medicinal chemistry 50 (10), 2293-2296, 2007
1662007
Cell cycle and biochemical effects of PD 0183812: a potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6
DW Fry, DC Bedford, PH Harvey, A Fritsch, PR Keller, Z Wu, E Dobrusin, ...
Journal of Biological Chemistry 276 (20), 16617-16623, 2001
1622001
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