Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance O Stepanek, AS Prabhakar, C Osswald, CG King, A Bulek, D Naeher, ... Cell 159 (2), 333-345, 2014 | 191 | 2014 |
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT WL Lo, NH Shah, N Ahsan, V Horkova, O Stepanek, AR Salomon, ... Nature immunology 19 (7), 733-741, 2018 | 155 | 2018 |
CD45 functions as a signaling gatekeeper in T cells AH Courtney, AA Shvets, W Lu, G Griffante, M Mollenauer, V Horkova, ... Science signaling 12 (604), eaaw8151, 2019 | 119 | 2019 |
Strong homeostatic TCR signals induce formation of self‐tolerant virtual memory CD8 T cells A Drobek, A Moudra, D Mueller, M Huranova, V Horkova, M Pribikova, ... The EMBO journal 37 (14), e98518, 2018 | 95 | 2018 |
Meta‐analysis of genotype‐phenotype associations in Bardet‐Biedl syndrome uncovers differences among causative genes V Niederlova, M Modrak, O Tsyklauri, M Huranova, O Stepanek Human Mutation 40 (11), 2068-2087, 2019 | 91 | 2019 |
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination WL Lo, NH Shah, SA Rubin, W Zhang, V Horkova, IR Fallahee, ... Nature immunology 20 (11), 1481-1493, 2019 | 79 | 2019 |
SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling P Draber, I Vonkova, O Stepanek, M Hrdinka, M Kucova, T Skopcova, ... Molecular and cellular biology 31 (22), 4550-4562, 2011 | 65 | 2011 |
CD8+ Tregs revisited: A heterogeneous population with different phenotypes and properties V Niederlova, O Tsyklauri, T Chadimova, O Stepanek European journal of immunology 51 (3), 512-530, 2021 | 63 | 2021 |
Palmitoylated transmembrane adaptor proteins in leukocyte signaling O Stepanek, P Draber, V Horejsi Cellular Signalling 26 (5), 895-902, 2014 | 47 | 2014 |
Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling O Stepanek, P Draber, A Drobek, V Horejsi, T Brdicka The Journal of Immunology 190 (4), 1807-1818, 2013 | 46 | 2013 |
Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148 O Stepanek, T Kalina, P Draber, T Skopcova, K Svojgr, P Angelisova, ... Journal of Biological Chemistry 286 (25), 22101-22112, 2011 | 41 | 2011 |
The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus MM Karimi, YA Guo, X Cui, HA Pallikonda, V Horková, YF Wang, SR Gil, ... Nature Communications 12 (1), 99, 2021 | 39 | 2021 |
Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation M Vobořil, T Brabec, J Dobeš, I Šplíchalová, J Březina, A Čepková, ... Nature Communications 11 (1), 2361, 2020 | 37 | 2020 |
Dynamics of the coreceptor-LCK interactions during T cell development shape the self-reactivity of peripheral CD4 and CD8 T cells V Horkova, A Drobek, D Mueller, C Gubser, V Niederlova, L Wyss, ... Cell reports 30 (5), 1504-1514. e7, 2020 | 36 | 2020 |
Bardet–Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self‐tolerance O Tsyklauri, V Niederlova, E Forsythe, A Prasai, A Drobek, P Kasparek, ... EMBO reports 22 (2), e50785, 2021 | 34 | 2021 |
Interaction of late apoptotic and necrotic cells with vitronectin O Stepanek, T Brdicka, P Angelisova, O Horvath, J Spicka, P Stockbauer, ... PLoS One 6 (5), e19243, 2011 | 30 | 2011 |
LST1/A is a myeloid leukocyte-specific transmembrane adaptor protein recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to the plasma membrane P Draber, O Stepanek, M Hrdinka, A Drobek, L Chmatal, L Mala, ... Journal of Biological Chemistry 287 (27), 22812-22821, 2012 | 27 | 2012 |
Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging A Moudra, V Niederlova, J Novotny, L Schmiedova, J Kubovciak, ... The Journal of Immunology 206 (9), 2109-2121, 2021 | 25 | 2021 |
The BBSome assembly is spatially controlled by BBS1 and BBS4 in human cells A Prasai, MS Cernohorska, K Ruppova, V Niederlova, M Andelova, ... Journal of Biological Chemistry 295 (42), 14279-14290, 2020 | 21 | 2020 |
Opposing effects of actin signaling and LFA‐1 on establishing the affinity threshold for inducing effector T‐cell responses in mice E Palmer, A Drobek, O Stepanek European journal of immunology 46 (8), 1887-1901, 2016 | 21 | 2016 |