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Ondřej Štěpánek
Ondřej Štěpánek
Group Leader, IMG Fellow, Institute of Molecular Genetics, Prague
在 img.cas.cz 的电子邮件经过验证
标题
引用次数
引用次数
年份
Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance
O Stepanek, AS Prabhakar, C Osswald, CG King, A Bulek, D Naeher, ...
Cell 159 (2), 333-345, 2014
1912014
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
WL Lo, NH Shah, N Ahsan, V Horkova, O Stepanek, AR Salomon, ...
Nature immunology 19 (7), 733-741, 2018
1552018
CD45 functions as a signaling gatekeeper in T cells
AH Courtney, AA Shvets, W Lu, G Griffante, M Mollenauer, V Horkova, ...
Science signaling 12 (604), eaaw8151, 2019
1192019
Strong homeostatic TCR signals induce formation of self‐tolerant virtual memory CD8 T cells
A Drobek, A Moudra, D Mueller, M Huranova, V Horkova, M Pribikova, ...
The EMBO journal 37 (14), e98518, 2018
952018
Meta‐analysis of genotype‐phenotype associations in Bardet‐Biedl syndrome uncovers differences among causative genes
V Niederlova, M Modrak, O Tsyklauri, M Huranova, O Stepanek
Human Mutation 40 (11), 2068-2087, 2019
912019
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination
WL Lo, NH Shah, SA Rubin, W Zhang, V Horkova, IR Fallahee, ...
Nature immunology 20 (11), 1481-1493, 2019
792019
SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling
P Draber, I Vonkova, O Stepanek, M Hrdinka, M Kucova, T Skopcova, ...
Molecular and cellular biology 31 (22), 4550-4562, 2011
652011
CD8+ Tregs revisited: A heterogeneous population with different phenotypes and properties
V Niederlova, O Tsyklauri, T Chadimova, O Stepanek
European journal of immunology 51 (3), 512-530, 2021
632021
Palmitoylated transmembrane adaptor proteins in leukocyte signaling
O Stepanek, P Draber, V Horejsi
Cellular Signalling 26 (5), 895-902, 2014
472014
Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling
O Stepanek, P Draber, A Drobek, V Horejsi, T Brdicka
The Journal of Immunology 190 (4), 1807-1818, 2013
462013
Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148
O Stepanek, T Kalina, P Draber, T Skopcova, K Svojgr, P Angelisova, ...
Journal of Biological Chemistry 286 (25), 22101-22112, 2011
412011
The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus
MM Karimi, YA Guo, X Cui, HA Pallikonda, V Horková, YF Wang, SR Gil, ...
Nature Communications 12 (1), 99, 2021
392021
Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation
M Vobořil, T Brabec, J Dobeš, I Šplíchalová, J Březina, A Čepková, ...
Nature Communications 11 (1), 2361, 2020
372020
Dynamics of the coreceptor-LCK interactions during T cell development shape the self-reactivity of peripheral CD4 and CD8 T cells
V Horkova, A Drobek, D Mueller, C Gubser, V Niederlova, L Wyss, ...
Cell reports 30 (5), 1504-1514. e7, 2020
362020
Bardet–Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self‐tolerance
O Tsyklauri, V Niederlova, E Forsythe, A Prasai, A Drobek, P Kasparek, ...
EMBO reports 22 (2), e50785, 2021
342021
Interaction of late apoptotic and necrotic cells with vitronectin
O Stepanek, T Brdicka, P Angelisova, O Horvath, J Spicka, P Stockbauer, ...
PLoS One 6 (5), e19243, 2011
302011
LST1/A is a myeloid leukocyte-specific transmembrane adaptor protein recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to the plasma membrane
P Draber, O Stepanek, M Hrdinka, A Drobek, L Chmatal, L Mala, ...
Journal of Biological Chemistry 287 (27), 22812-22821, 2012
272012
Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging
A Moudra, V Niederlova, J Novotny, L Schmiedova, J Kubovciak, ...
The Journal of Immunology 206 (9), 2109-2121, 2021
252021
The BBSome assembly is spatially controlled by BBS1 and BBS4 in human cells
A Prasai, MS Cernohorska, K Ruppova, V Niederlova, M Andelova, ...
Journal of Biological Chemistry 295 (42), 14279-14290, 2020
212020
Opposing effects of actin signaling and LFA‐1 on establishing the affinity threshold for inducing effector T‐cell responses in mice
E Palmer, A Drobek, O Stepanek
European journal of immunology 46 (8), 1887-1901, 2016
212016
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