| Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis CA Flaveny, K Griffett, BEDM El-Gendy, M Kazantzis, M Sengupta, ... Cancer cell 28 (1), 42-56, 2015 | 199 | 2015 |
| Reviving antibiotics: efflux pump inhibitors that interact with AcrA, a membrane fusion protein of the AcrAB-TolC multidrug efflux pump N Abdali, JM Parks, KM Haynes, JL Chaney, AT Green, D Wolloscheck, ... ACS infectious diseases 3 (1), 89-98, 2017 | 111 | 2017 |
| Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain Z Chen, TM Doyle, L Luongo, TM Largent-Milnes, LA Giancotti, G Kolar, ... Proceedings of the National Academy of Sciences 116 (21), 10557-10562, 2019 | 86 | 2019 |
| Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase SR Selness, RV Devraj, B Devadas, JK Walker, TL Boehm, RC Durley, ... Bioorganic & medicinal chemistry letters 21 (13), 4066-4071, 2011 | 72 | 2011 |
| Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804 L Xing, HS Shieh, SR Selness, RV Devraj, JK Walker, B Devadas, ... Biochemistry 48 (27), 6402-6411, 2009 | 65 | 2009 |
| Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa CJ Cooper, G Krishnamoorthy, D Wolloscheck, JK Walker, VV Rybenkov, ... ACS infectious diseases 4 (8), 1223-1234, 2018 | 64 | 2018 |
| Substituted pyridinones B Devadas, J Walker, S Selness, T Boehm, R Durley, R Devraj, B Hickory, ... US Patent App. 10/918,826, 2005 | 61 | 2005 |
| Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli KM Haynes, N Abdali, V Jhawar, HI Zgurskaya, JM Parks, AT Green, ... Journal of medicinal chemistry 60 (14), 6205-6219, 2017 | 56 | 2017 |
| New fluorobutenolide templates for synthesis TB Patrick, MV Lanahan, C Yang, JK Walker, CL Hutchinson, BE Neal The Journal of Organic Chemistry 59 (5), 1210-1212, 1994 | 56 | 1994 |
| Substituted pyridinones B Devadas, J Walker, SR Selness, TL Boehm, RC Durley, R Devraj, ... US Patent 7,067,540, 2006 | 55 | 2006 |
| Substituted pyrazoles as p38 kinase inhibitors AS Naraian, M Clare, PW Collins, JZ Crich, R Devraj, DL Flynn, L Geng, ... US Patent 6,979,686, 2005 | 43 | 2005 |
| Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold AT Green, M Moniruzzaman, CJ Cooper, JK Walker, JC Smith, JM Parks, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (6), 129546, 2020 | 42 | 2020 |
| Discovery and characterization of atropisomer PH‐797804, a p38 MAP kinase inhibitor, as a clinical drug candidate L Xing, B Devadas, RV Devraj, SR Selness, H Shieh, JK Walker, M Mao, ... ChemMedChem 7 (2), 273-280, 2012 | 40 | 2012 |
| 1-(2-(2, 2, 2-Trifluoroethoxy) ethyl-1H-pyrazolo [4, 3-d] pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors MB Tollefson, BA Acker, EJ Jacobsen, RO Hughes, JK Walker, DNA Fox, ... Bioorganic & medicinal chemistry letters 20 (10), 3125-3128, 2010 | 38 | 2010 |
| Therapeutic effect of a synthetic RORα/γ agonist in an animal model of autism Y Wang, C Billon, JK Walker, TP Burris ACS Chemical Neuroscience 7 (2), 143-148, 2016 | 36 | 2016 |
| Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase SR Selness, RV Devraj, JB Monahan, TL Boehm, JK Walker, B Devadas, ... Bioorganic & medicinal chemistry letters 19 (20), 5851-5856, 2009 | 36 | 2009 |
| Acute Lymphoid and Gastrointestinal Toxicity Induced by Selective p38α Map Kinase and Map Kinase–Activated Protein Kinase-2 (MK2) Inhibitors in the Dog DL Morris, SP O’Neil, RV Devraj, JP Portanova, RW Gilles, CJ Gross, ... Toxicologic pathology 38 (4), 606-618, 2010 | 33 | 2010 |
| Cationic [5+ 2] cycloaddition reactions promoted by trimethylsilyl triflate in highly polar media JL Collins, PA Grieco, JK Walker Tetrahedron letters 38 (8), 1321-1324, 1997 | 31 | 1997 |
| Multidrug efflux pumps and the two-faced Janus of substrates and inhibitors HI Zgurskaya, JK Walker, JM Parks, VV Rybenkov Accounts of chemical research 54 (4), 930-939, 2021 | 30 | 2021 |
| Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa J Mehla, G Malloci, R Mansbach, CA López, R Tsivkovski, K Haynes, ... MBio 12 (1), 10.1128/mbio. 02785-20, 2021 | 28 | 2021 |
Helen ZgurskayaProfessor of Chemistry and Biochemistry在 ou.edu 的电子邮件经过验证
