Epigenetic differences arise during the lifetime of monozygotic twins MF Fraga, E Ballestar, MF Paz, S Ropero, F Setien, ML Ballestar, ... Proceedings of the National Academy of Sciences 102 (30), 10604-10609, 2005 | 4422 | 2005 |
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer MF Fraga, E Ballestar, A Villar-Garea, M Boix-Chornet, J Espada, ... Nature genetics 37 (4), 391-400, 2005 | 2395 | 2005 |
Autophagy maintains stemness by preventing senescence L García-Prat, M Martínez-Vicente, E Perdiguero, L Ortet, ... Nature 529 (7584), 37-42, 2016 | 1270 | 2016 |
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells A Lujambio, S Ropero, E Ballestar, MF Fraga, C Cerrato, F Setién, ... Cancer research 67 (4), 1424-1429, 2007 | 1152 | 2007 |
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation PA Wade, A Gegonne, PL Jones, E Ballestar, F Aubry, AP Wolffe Nature genetics 23 (1), 62-66, 1999 | 1052 | 1999 |
Geriatric muscle stem cells switch reversible quiescence into senescence P Sousa-Victor, S Gutarra, L García-Prat, J Rodriguez-Ubreva, L Ortet, ... Nature 506 (7488), 316-321, 2014 | 963 | 2014 |
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex H Peinado, E Ballestar, M Esteller, A Cano Molecular and cellular biology, 2004 | 938 | 2004 |
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus BM Javierre, AF Fernandez, J Richter, F Al-Shahrour, JI Martin-Subero, ... Genome research 20 (2), 170-179, 2010 | 733 | 2010 |
Notch signaling is essential for ventricular chamber development J Grego-Bessa, L Luna-Zurita, G del Monte, V Bolós, P Melgar, ... Developmental cell 12 (3), 415-429, 2007 | 572 | 2007 |
Methyl‐CpG‐binding proteins: Targeting specific gene repression E Ballestar, AP Wolffe European journal of biochemistry 268 (1), 1-6, 2001 | 491 | 2001 |
Data integration in the era of omics: current and future challenges D Gomez-Cabrero, I Abugessaisa, D Maier, A Teschendorff, ... BMC systems biology 8, 1-10, 2014 | 477 | 2014 |
A DNA methylation fingerprint of 1628 human samples AF Fernandez, Y Assenov, JI Martin-Subero, B Balint, R Siebert, ... Genome research 22 (2), 407-419, 2012 | 475 | 2012 |
Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer O Aguilera, MF Fraga, E Ballestar, MF Paz, M Herranz, J Espada, ... Oncogene 25 (29), 4116-4121, 2006 | 458 | 2006 |
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer E Ballestar, MF Paz, L Valle, S Wei, MF Fraga, J Espada, JC Cigudosa, ... The EMBO journal 22 (23), 6335-6345, 2003 | 424 | 2003 |
DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E G Lund, L Andersson, M Lauria, M Lindholm, MF Fraga, A Villar-Garea, ... Journal of Biological Chemistry 279 (28), 29147-29154, 2004 | 420 | 2004 |
Epigenetic control of myeloid cell differentiation, identity and function D Álvarez-Errico, R Vento-Tormo, M Sieweke, E Ballestar Nature Reviews Immunology 15 (1), 7-17, 2015 | 348 | 2015 |
A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition S Ropero, MF Fraga, E Ballestar, R Hamelin, H Yamamoto, ... Nature genetics 38 (5), 566-569, 2006 | 348 | 2006 |
The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties MF Fraga, E Ballestar, G Montoya, P Taysavang, PA Wade, M Esteller Nucleic acids research 31 (6), 1765-1774, 2003 | 323 | 2003 |
A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors MF Fraga, M Herranz, J Espada, E Ballestar, MF Paz, S Ropero, E Erkek, ... Cancer research 64 (16), 5527-5534, 2004 | 306 | 2004 |
The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer AF Fernandez, C Rosales, P Lopez-Nieva, O Graña, E Ballestar, ... Genome research 19 (3), 438-451, 2009 | 303 | 2009 |