Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer A Pasternak, FJ Hernandez, LM Rasmussen, B Vester, J Wengel Nucleic acids research 39 (3), 1155-1164, 2011 | 190 | 2011 |
G-quadruplex-forming aptamers—characteristics, applications, and perspectives C Roxo, W Kotkowiak, A Pasternak Molecules 24 (20), 3781, 2019 | 172 | 2019 |
UNA (unlocked nucleic acid): a flexible RNA mimic that allows engineering of nucleic acid duplex stability N Langkjær, A Pasternak, J Wengel Bioorganic & medicinal chemistry 17 (15), 5420-5425, 2009 | 155 | 2009 |
The influence of locked nucleic acid residues on the thermodynamic properties of 2′-O-methyl RNA/RNA heteroduplexes E Kierzek, A Ciesielska, K Pasternak, DH Mathews, DH Turner, R Kierzek Nucleic acids research 33 (16), 5082-5093, 2005 | 128 | 2005 |
Unlocked nucleic acid–an RNA modification with broad potential A Pasternak, J Wengel Organic & biomolecular chemistry 9 (10), 3591-3597, 2011 | 82 | 2011 |
Thermodynamics of RNA duplexes modified with unlocked nucleic acid nucleotides A Pasternak, J Wengel Nucleic acids research 38 (19), 6697-6706, 2010 | 62 | 2010 |
Contributions of Stacking, Preorganization, and Hydrogen Bonding to the Thermodynamic Stability of Duplexes between RNA and 2′-O-Methyl RNA with Locked … E Kierzek, A Pasternak, K Pasternak, Z Gdaniec, I Yildirim, DH Turner, ... Biochemistry 48 (20), 4377-4387, 2009 | 55 | 2009 |
Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2′-C-piperazino-UNA monomer TB Jensen, JR Henriksen, BE Rasmussen, LM Rasmussen, TL Andresen, ... Bioorganic & medicinal chemistry 19 (16), 4739-4745, 2011 | 51 | 2011 |
Nearest neighbor parameters for Watson–Crick complementary heteroduplexes formed between 2′-O-methyl RNA and RNA oligonucleotides E Kierzek, DH Mathews, A Ciesielska, DH Turner, R Kierzek Nucleic acids research 34 (13), 3609-3614, 2006 | 50 | 2006 |
Thermodynamic, anticoagulant, and antiproliferative properties of thrombin binding aptamer containing novel UNA derivative W Kotkowiak, J Lisowiec-Wachnicka, J Grynda, R Kierzek, J Wengel, ... Molecular Therapy-Nucleic Acids 10, 304-316, 2018 | 49 | 2018 |
Modulation of i-motif thermodynamic stability by the introduction of UNA (unlocked nucleic acid) monomers A Pasternak, J Wengel Bioorganic & medicinal chemistry letters 21 (2), 752-755, 2011 | 46 | 2011 |
A chemical synthesis of LNA-2, 6-diaminopurine riboside, and the influence of 2′-O-methyl-2, 6-diaminopurine and LNA-2, 6-diaminopurine ribosides on the thermodynamic … A Pasternak, E Kierzek, K Pasternak, DH Turner, R Kierzek Nucleic acids research 35 (12), 4055-4063, 2007 | 39 | 2007 |
The Thermodynamics of 3‘-Terminal Pyrene and Guanosine for the Design of Isoenergetic 2‘-O-Methyl-RNA-LNA Chimeric Oligonucleotide Probes of RNA Structure A Pasternak, E Kierzek, K Pasternak, A Fratczak, DH Turner, R Kierzek Biochemistry 47 (5), 1249-1258, 2008 | 31 | 2008 |
Improved RE31 analogues containing modified nucleic acid monomers: Thermodynamic, structural, and biological effects W Kotkowiak, J Wengel, CJ Scotton, A Pasternak Journal of Medicinal Chemistry 62 (5), 2499-2507, 2019 | 26 | 2019 |
Thermodynamic features of structural motifs formed by β-L-RNA M Szabat, D Gudanis, W Kotkowiak, Z Gdaniec, R Kierzek, A Pasternak PLoS One 11 (2), e0149478, 2016 | 26 | 2016 |
Pyrene‐Modified Unlocked Nucleic Acids: Synthesis, Thermodynamic Studies, and Fluorescent Properties KK Karlsen, A Pasternak, TB Jensen, J Wengel ChemBioChem 13 (4), 590-601, 2012 | 26 | 2012 |
Unlocked nucleic acids: implications of increased conformational flexibility for RNA/DNA triplex formation W Kotkowiak, M Kotkowiak, R Kierzek, A Pasternak Biochemical Journal 464 (2), 203-211, 2014 | 23 | 2014 |
A systematic study on the influence of thermodynamic asymmetry of 5′-ends of siRNA duplexes in relation to their silencing potency J Lisowiec-Wąchnicka, N Bartyś, A Pasternak Scientific reports 9 (1), 2477, 2019 | 19 | 2019 |
Beyond G-quadruplexes—the effect of junction with additional structural motifs on aptamers properties W Kotkowiak, A Pasternak International Journal of Molecular Sciences 22 (18), 9948, 2021 | 16 | 2021 |
Photoligation of self-assembled DNA constructs containing anthracene-functionalized 2′-amino-LNA monomers K Pasternak, A Pasternak, P Gupta, RN Veedu, J Wengel Bioorganic & medicinal chemistry 19 (24), 7407-7415, 2011 | 15 | 2011 |