| Structure of prolyl-tRNA synthetase-halofuginone complex provides basis for development of drugs against malaria and toxoplasmosis V Jain, M Yogavel, Y Oshima, H Kikuchi, B Touquet, MA Hakimi, ... Structure 23 (5), 819-829, 2015 | 109 | 2015 |
| Targeting prolyl-tRNA synthetase to accelerate drug discovery against malaria, leishmaniasis, toxoplasmosis, cryptosporidiosis, and coccidiosis V Jain, M Yogavel, H Kikuchi, Y Oshima, N Hariguchi, M Matsumoto, ... Structure 25 (10), 1495-1505. e6, 2017 | 76 | 2017 |
| Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding LC Walters, K Harlos, S Brackenridge, D Rozbesky, JR Barrett, V Jain, ... Nature communications 9 (1), 3137, 2018 | 64 | 2018 |
| Detection of Mycobacterium tuberculosis GlcB or HspX Antigens or devR DNA Impacts the Rapid Diagnosis of Tuberculous Meningitis in Children S Haldar, N Sankhyan, N Sharma, A Bansal, V Jain, VK Gupta, M Juneja, ... Public Library of Science 7 (9), e44630, 2012 | 63 | 2012 |
| Drug targeting of one or more aminoacyl-tRNA synthetase in the malaria parasite Plasmodium falciparum Y Manickam, R Chaturvedi, P Babbar, N Malhotra, V Jain, A Sharma Drug discovery today 23 (6), 1233-1240, 2018 | 51 | 2018 |
| Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase V Jain, H Kikuchi, Y Oshima, A Sharma, M Yogavel Journal of structural and functional genomics 15, 181-190, 2014 | 47 | 2014 |
| Structure of 6-hydroxymethyl-7, 8-dihydropterin pyrophosphokinase–dihydropteroate synthase from Plasmodium vivax sheds light on drug resistance M Yogavel, JE Nettleship, A Sharma, K Harlos, A Jamwal, R Chaturvedi, ... Journal of Biological Chemistry 293 (39), 14962-14972, 2018 | 17 | 2018 |
| Dimerization of arginyl-tRNA synthetase by free heme drives its inactivation in Plasmodium falciparum V Jain, M Yogavel, A Sharma Structure 24 (9), 1476-1487, 2016 | 17 | 2016 |
| Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning D Rozbesky, RA Robinson, V Jain, M Renner, T Malinauskas, K Harlos, ... Nature communications 10 (1), 3691, 2019 | 16 | 2019 |
| Structure-based targeting of orthologous pathogen proteins accelerates antiparasitic drug discovery V Jain, A Sharma, G Singh, M Yogavel, A Sharma ACS Infectious Diseases 3 (4), 281-292, 2017 | 15 | 2017 |
| Repurposing of potent drug candidates for multiparasite targeting V Jain, A Sharma Trends in parasitology 33 (3), 158-161, 2017 | 15 | 2017 |
| Structural and functional analysis of Glutaminyl-tRNA synthetase (TtGlnRS) from Thermus thermophilus HB8 and its complexes M Nachiappan, V Jain, A Sharma, M Yogavel, J Jeyakanthan International journal of biological macromolecules 120, 1379-1386, 2018 | 13 | 2018 |
| Conformational changes in glutaminyl-tRNA synthetases upon binding of the substrates and analogs using molecular docking and molecular dynamics approaches M Nachiappan, V Jain, A Sharma, Y Manickam, J Jeyakanthan Journal of Biomolecular Structure and Dynamics, 2019 | 9 | 2019 |
| Drosophila OTK Is a Glycosaminoglycan-Binding Protein with High Conformational Flexibility D Rozbesky, J Monistrol, V Jain, J Hillier, S Padilla-Parra, EY Jones Structure 28 (5), 507-515. e5, 2020 | 3 | 2020 |
| Semaphorin 3A induces cytoskeletal paralysis in tumor-specific CD8+ T cells MB Barnkob, YS Michaels, V André, PS Macklin, U Gileadi, S Valvo, ... BioRxiv, 849083, 2019 | 2 | 2019 |
| Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells MB Barnkob, YS Michaels, V André, PS Macklin, U Gileadi, S Valvo, ... nature communications 15 (1), 3173, 2024 | | 2024 |
| Structural comparison of inhibitors bound to parasitic PRS enzymes Y Manickam, V Jain, H Kikuchi, A Sharma Acta Crystallographica Section A: Foundations and Advances 73, C225-C225, 2017 | | 2017 |
| MS009. P01 Y Manickam, V Jain, H Kikuchi, A Sharma Acta Cryst 70, C225, 2017 | | 2017 |
| Structural comparison of inhibitors bound to parasitic PRS enzymes Y Manickam, V Jain, H Kikuchi, A Sharma ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70, C225-C225, 2014 | | 2014 |
Yogavel ManickamResearch Scientist (P), ICGEB, New Delhi在 icgeb.res.in 的电子邮件经过验证
