| Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease JF Emile, EL Diamond, Z Hélias-Rodzewicz, F Cohen-Aubart, F Charlotte, ... Blood, The Journal of the American Society of Hematology 124 (19), 3016-3019, 2014 | 247 | 2014 |
| Clinical Relevance of KRAS-Mutated Subclones Detected with Picodroplet Digital PCR in Advanced Colorectal Cancer Treated with Anti-EGFR Therapy P Laurent-Puig, D Pekin, C Normand, SK Kotsopoulos, P Nizard, ... Clinical cancer research 21 (5), 1087-1097, 2015 | 177 | 2015 |
| Stress‐induced retrotranslocation of clusterin/ApoJ into the cytosol P Nizard, S Tetley, Y Le Dréan, T Watrin, P Le Goff, MR Wilson, D Michel Traffic 8 (5), 554-565, 2007 | 168 | 2007 |
| Up-regulation of the clusterin gene after proteotoxic stress: implication of HSF1–HSF2 heterocomplexes F Loison, L Debure, P Nizard, P Le Goff, D Michel, Y Le Dréan Biochemical Journal 395 (1), 223-231, 2006 | 151 | 2006 |
| A study of hypermethylated circulating tumor DNA as a universal colorectal cancer biomarker S Garrigou, G Perkins, F Garlan, C Normand, A Didelot, D Le Corre, ... Clinical chemistry 62 (8), 1129-1139, 2016 | 145 | 2016 |
| Membrane protein insertion regulated by bringing electrostatic and hydrophobic interactions into play: A case study with the translocation domain of the diphtheria toxin A Chenal, P Savarin, P Nizard, F Guillain, D Gillet, V Forge Journal of Biological Chemistry 277 (45), 43425-43432, 2002 | 96 | 2002 |
| Circulating cell‐free BRAFV600E as a biomarker in children with Langerhans cell histiocytosis S Héritier, Z Hélias‐Rodzewicz, H Lapillonne, N Terrones, S Garrigou, ... British journal of haematology 178 (3), 457-467, 2017 | 88 | 2017 |
| High-throughput multiplexed fluorescence-activated droplet sorting O Caen, S Schütz, MSS Jammalamadaka, J Vrignon, P Nizard, ... Microsystems & nanoengineering 4 (1), 33, 2018 | 80 | 2018 |
| High throughput single cell counting in droplet-based microfluidics H Lu, O Caen, J Vrignon, E Zonta, Z El Harrak, P Nizard, JC Baret, V Taly Scientific Reports 7 (1), 1366, 2017 | 77 | 2017 |
| A ubiquitin-based assay for the cytosolic uptake of protein transduction domains F Loison, P Nizard, T Sourisseau, P Le Goff, L Debure, Y Le Drean, ... Molecular Therapy 11 (2), 205-214, 2005 | 68 | 2005 |
| Assessment of DNA integrity, applications for cancer research E Zonta, P Nizard, V Taly Advances in clinical chemistry 70, 197-246, 2015 | 63 | 2015 |
| Microfluidics as a strategic player to decipher single-cell omics? O Caen, H Lu, P Nizard, V Taly Trends in biotechnology 35 (8), 713-727, 2017 | 46 | 2017 |
| Structure and function of diphtheria toxin: from pathology to engineering A Chenal, P Nizard, D Gillet Journal of Toxicology: Toxin Reviews 21 (4), 321-359, 2002 | 44 | 2002 |
| Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain A Chenal, P Nizard, V Forge, M Pugniere, MO Roy, JC Mani, F Guillain, ... Protein engineering 15 (5), 383-391, 2002 | 41 | 2002 |
| Beyond the on/off chip trade-off: A reversibly sealed microfluidic platform for 3D tumor microtissue analysis G Pitingolo, P Nizard, A Riaud, V Taly Sensors and Actuators B: Chemical 274, 393-401, 2018 | 31 | 2018 |
| Prolonged display or rapid internalization of the IgG-binding protein ZZ anchored to the surface of cells using the diphtheria toxin T domain P Nizard, A Chenal, B Beaumelle, A Fourcade, D Gillet Protein Engineering 14 (6), 439-446, 2001 | 30 | 2001 |
| Anchoring antibodies to membranes using a diphtheria toxin T domain‐ZZ fusion protein as a pH sensitive membrane anchor P Nizard, D Liger, C Gaillard, D Gillet FEBS letters 433 (1-2), 83-88, 1998 | 27 | 1998 |
| Anchoring cytokines to tumor cells for the preparation of anticancer vaccines without gene transfection in mice P Nizard, DA Gross, A Babon, A Chenal, B Beaumelle, K Kosmatopoulos, ... Journal of Immunotherapy 26 (1), 63-71, 2003 | 22 | 2003 |
| The diphtheria toxin transmembrane domain as a pH sensitive membrane anchor for human interleukin-2 and murine interleukin-3. D Liger, P Nizard, C Gaillard, JC VanderSpek, JR Murphy, B Pitard, ... Protein engineering 11 (11), 1111-1120, 1998 | 20 | 1998 |
| Development of digital PCR molecular tests for clinical practice: principles, practical implementation and recommendations JA Denis, J Nectoux, PJ Lamy, CR Le Sciellour, H Guermouche, AS Alary, ... Annales de biologie clinique 76 (5), 505-523, 2018 | 19 | 2018 |
