| Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels F Chiara, D Castellaro, O Marin, V Petronilli, WS Brusilow, M Juhaszova, ... PloS one 3 (3), e1852, 2008 | 335 | 2008 |
| Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition A Rasola, M Sciacovelli, F Chiara, B Pantic, WS Brusilow, P Bernardi Proceedings of the National Academy of Sciences 107 (2), 726-731, 2010 | 267 | 2010 |
| Gold (III)‐dithiocarbamato anticancer agents: Activity, toxicology and histopathological studies in rodents C Marzano, L Ronconi, F Chiara, MC Giron, I Faustinelli, P Cristofori, ... International journal of cancer 129 (2), 487-496, 2011 | 119 | 2011 |
| Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro MG Martin, S Perga, L Trovo, A Rasola, P Holm, T Rantamäki, T Harkany, ... Molecular Biology of the Cell 19 (5), 2101-2112, 2008 | 112 | 2008 |
| Absence of neurofibromin induces an oncogenic metabolic switch via mitochondrial ERK-mediated phosphorylation of the chaperone TRAP1 I Masgras, F Ciscato, AM Brunati, E Tibaldi, S Indraccolo, M Curtarello, ... Cell reports 18 (3), 659-672, 2017 | 90 | 2017 |
| Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death F Chiara, A Gambalunga, M Sciacovelli, A Nicolli, L Ronconi, D Fregona, ... Cell death & disease 3 (12), e444-e444, 2012 | 79 | 2012 |
| Hexokinase 2 displacement from mitochondria‐associated membranes prompts Ca2+‐dependent death of cancer cells F Ciscato, R Filadi, I Masgras, M Pizzi, O Marin, N Damiano, P Pizzo, ... EMBO reports 21 (7), e49117, 2020 | 78 | 2020 |
| Autoinhibition of the platelet-derived growth factor β-receptor tyrosine kinase by its C-terminal tail F Chiara, S Bishayee, CH Heldin, JB Demoulin Journal of Biological Chemistry 279 (19), 19732-19738, 2004 | 76 | 2004 |
| GSK-3 and mitochondria in cancer cells F Chiara, A Rasola Frontiers in oncology 3, 16, 2013 | 66 | 2013 |
| Mutations in the met oncogene unveil a “dual switch” mechanism controlling tyrosine kinase activity F Chiara, P Michieli, L Pugliese, PM Comoglio Journal of biological chemistry 278 (31), 29352-29358, 2003 | 61 | 2003 |
| Hepatitis B vaccination of adolescents: significance of non-protective antibodies F Chiara, GB Bartolucci, M Cattai, A Piazza, A Nicolli, A Buja, A Trevisan Vaccine 32 (1), 62-68, 2013 | 41 | 2013 |
| Cyp46-mediated cholesterol loss promotes survival in stressed hippocampal neurons MG Martin, L Trovò, S Perga, A Sadowska, A Rasola, F Chiara, CG Dotti Neurobiology of aging 32 (5), 933-943, 2011 | 40 | 2011 |
| Hepatitis B vaccination at three months of age: a successful strategy? F Chiara, GB Bartolucci, M Mongillo, L Ferretto, A Nicolli, A Trevisan Vaccine 31 (13), 1696-1700, 2013 | 39 | 2013 |
| Gold (III)–pyrrolidinedithiocarbamato derivatives as antineoplastic agents C Nardon, F Chiara, L Brustolin, A Gambalunga, F Ciscato, A Rasola, ... ChemistryOpen 4 (2), 183-191, 2015 | 31 | 2015 |
| A gain of function mutation in the activation loop of plateletderived growth factor β-receptor deregulates its kinase activity F Chiara, MJ Goumans, H Forsberg, A Ahgrén, A Rasola, P Aspenström, ... Journal of Biological Chemistry 279 (41), 42516-42527, 2004 | 31 | 2004 |
| Ru (III) anticancer agents with aromatic and non-aromatic dithiocarbamates as ligands: Loading into nanocarriers and preliminary biological studies S Scintilla, L Brustolin, A Gambalunga, F Chiara, A Trevisan, C Nardon, ... Journal of Inorganic Biochemistry 165, 159-169, 2016 | 28 | 2016 |
| A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure AA Jambekar, E Palma, L Nicolosi, A Rasola, V Petronilli, F Chiara, ... Liver International 31 (8), 1209-1221, 2011 | 27 | 2011 |
| Gadd45α activity is the principal effector of Shigella mitochondria-dependent epithelial cell death in vitro and ex vivo L Lembo-Fazio, G Nigro, G Noël, G Rossi, F Chiara, K Tsilingiri, ... Cell death & disease 2 (2), e122-e122, 2011 | 25 | 2011 |
| Tetanus vaccination, antibody persistence and decennial booster: a serosurvey of university students and at-risk workers M BORELLA-VENTURINI, C Frasson, F Paluan, D DE NUZZO, G DI MASI, ... Epidemiology & Infection 145 (9), 1757-1762, 2017 | 23 | 2017 |
| Synthesis, chemical characterization and cancer cell growth-inhibitory activities of Cu (ii) and Ru (iii) aliphatic and aromatic dithiocarbamato complexes L Brustolin, C Nardon, N Pettenuzzo, NZ Fantoni, S Quarta, F Chiara, ... Dalton Transactions 47 (43), 15477-15486, 2018 | 20 | 2018 |
