The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decade RJ Kathawala, P Gupta, CR Ashby Jr, ZS Chen Drug resistance updates 18, 1-17, 2015 | 771 | 2015 |
Multidrug resistance associated proteins in multidrug resistance K Sodani, A Patel, RJ Kathawala, ZS Chen Chinese journal of cancer 31 (2), 58, 2012 | 326 | 2012 |
Tyrosine kinase inhibitors as reversal agents for ABC transporter mediated drug resistance N Anreddy, P Gupta, RJ Kathawala, A Patel, JND Wurpel, ZS Chen Molecules 19 (9), 13848-13877, 2014 | 120 | 2014 |
Repositioning of tyrosine kinase inhibitors as antagonists of ATP-binding cassette transporters in anticancer drug resistance YJ Wang, YK Zhang, RJ Kathawala, ZS Chen Cancers 6 (4), 1925-1952, 2014 | 79 | 2014 |
In vitro, in vivo and ex vivo characterization of ibrutinib: a potent inhibitor of the efflux function of the transporter MRP1 H Zhang, A Patel, SL Ma, XJ Li, YK Zhang, PQ Yang, RJ Kathawala, ... British journal of pharmacology 171 (24), 5845-5857, 2014 | 66 | 2014 |
Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs RJ Kathawala, YJ Wang, CR Ashby Jr, ZS Chen Chinese journal of cancer 33 (5), 223, 2014 | 66 | 2014 |
Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1 YJ Wang, RJ Kathawala, YK Zhang, A Patel, P Kumar, S Shukla, KL Fung, ... Biochemical pharmacology 90 (4), 367-378, 2014 | 61 | 2014 |
Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo K Sodani, A Patel, N Anreddy, S Singh, DH Yang, RJ Kathawala, P Kumar, ... Biochemical pharmacology 89 (1), 52-61, 2014 | 59 | 2014 |
Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2 DS Wang, A Patel, S Shukla, YK Zhang, YJ Wang, RJ Kathawala, ... Oncotarget 5 (12), 4529, 2014 | 47 | 2014 |
Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents YK Zhang, H Zhang, GN Zhang, YJ Wang, RJ Kathawala, R Si, BA Patel, ... Oncotarget 6 (27), 24277, 2015 | 44 | 2015 |
Masitinib Antagonizes ATP-Binding Cassette Subfamily C Member 10-Mediated Paclitaxel Resistance: A Preclinical Study. RJ Kathawala, K Sodani, K Chen, AS Patel, AH Abuznait, N Anreddy, ... Molecular Cancer Therapeutics, 2014 | 44 | 2014 |
Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10) W Deng, CL Dai, JJ Chen, RJ Kathawala, YL Sun, HF Chen, LW Fu, ... Oncology reports 29 (6), 2479-2485, 2013 | 42 | 2013 |
The BTK inhibitor ibrutinib (PCI-32765) overcomes paclitaxel resistance in ABCB1-and ABCC10-overexpressing cells and tumors H Zhang, A Patel, YJ Wang, YK Zhang, RJ Kathawala, LH Qiu, BA Patel, ... Molecular cancer therapeutics 16 (6), 1021-1030, 2017 | 38 | 2017 |
AST1306, a potent EGFR inhibitor, antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance H Zhang, YJ Wang, YK Zhang, DS Wang, RJ Kathawala, A Patel, ... Cancer letters 350 (1-2), 61-68, 2014 | 38 | 2014 |
Linsitinib (OSI-906) antagonizes ATP-binding cassette subfamily G member 2 and subfamily C member 10-mediated drug resistance H Zhang, RJ Kathawala, YJ Wang, YK Zhang, A Patel, S Shukla, ... The international journal of biochemistry & cell biology 51, 111-119, 2014 | 38 | 2014 |
A-803467, a tetrodotoxin-resistant sodium channel blocker, modulates ABCG2-mediated MDR in vitro and in vivo N Anreddy, A Patel, YK Zhang, YJ Wang, S Shukla, RJ Kathawala, ... Oncotarget 6 (36), 39276, 2015 | 34 | 2015 |
The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study. RJ Kathawala, L Wei, N Anreddy, K Chen, A Patel, S Alqahtani, YK Zhang, ... Researchgate, 1-12, 2014 | 34 | 2014 |
PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR N Anreddy, A Patel, K Sodani, RJ Kathawala, EP Chen, JND Wurpel, ... Acta Pharmaceutica Sinica B 4 (3), 202-207, 2014 | 34 | 2014 |
Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance RJ Kathawala, JJ Chen, YK Zhang, YJ Wang, A Patel, DS Wang, ... International journal of oncology 44 (5), 1634-1642, 2014 | 33 | 2014 |
Tivozanib reverses multidrug resistance mediated by ABCB1 (P-glycoprotein) and ABCG2 (BCRP). D Yang, RJ Kathawala, EE Chufan, A Patel, SV Ambudkar, ZS Chen, ... Future Oncology, 2013 | 32 | 2013 |