Identification of a serotonin/glutamate receptor complex implicated in psychosis J González-Maeso, RL Ang, T Yuen, P Chan, NV Weisstaub, ... Nature 452 (7183), 93-97, 2008 | 933 | 2008 |
Promoting transparency and reproducibility in enhanced molecular simulations Nature methods 16 (8), 670-673, 2019 | 684 | 2019 |
G protein–coupled receptor oligomerization revisited: functional and pharmacological perspectives S Ferré, V Casadó, LA Devi, M Filizola, R Jockers, MJ Lohse, G Milligan, ... Pharmacological reviews 66 (2), 413-434, 2014 | 597 | 2014 |
Dopamine D2 receptors form higher order oligomers at physiological expression levels W Guo, E Urizar, M Kralikova, JC Mobarec, L Shi, M Filizola, JA Javitch The EMBO journal 27 (17), 2293-2304, 2008 | 378 | 2008 |
International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers JP Pin, R Neubig, M Bouvier, L Devi, M Filizola, JA Javitch, MJ Lohse, ... Pharmacological reviews 59 (1), 5-13, 2007 | 330 | 2007 |
Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs M Fribourg, JL Moreno, T Holloway, D Provasi, L Baki, R Mahajan, G Park, ... Cell 147 (5), 1011-1023, 2011 | 320 | 2011 |
Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation W Guo, L Shi, M Filizola, H Weinstein, JA Javitch Proceedings of the National Academy of Sciences 102 (48), 17495-17500, 2005 | 319 | 2005 |
Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators AC Kruegel, MM Gassaway, A Kapoor, A Váradi, S Majumdar, M Filizola, ... Journal of the American Chemical Society 138 (21), 6754-6764, 2016 | 303 | 2016 |
Modern homology modeling of G-protein coupled receptors: which structural template to use? JC Mobarec, R Sanchez, M Filizola Journal of medicinal chemistry 52 (16), 5207-5216, 2009 | 178 | 2009 |
Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity I Gomes, W Fujita, A Gupta, SA Saldanha, A Negri, CE Pinello, C Eberhart, ... Proceedings of the National Academy of Sciences 110 (29), 12072-12077, 2013 | 145 | 2013 |
Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening J Zhu, J Zhu, A Negri, D Provasi, M Filizola, BS Coller, TA Springer Blood, The Journal of the American Society of Hematology 116 (23), 5050-5059, 2010 | 138 | 2010 |
Membrane driven spatial organization of GPCRs S Mondal, JM Johnston, H Wang, G Khelashvili, M Filizola, H Weinstein Scientific reports 3 (1), 2909, 2013 | 127 | 2013 |
Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy N Coudray, S Valvo, M Hu, R Lasala, C Kim, M Vink, M Zhou, D Provasi, ... Proceedings of the National Academy of Sciences 110 (6), 2140-2145, 2013 | 120 | 2013 |
The study of G‐protein coupled receptor oligomerization with computational modeling and bioinformatics M Filizola, H Weinstein The FEBS journal 272 (12), 2926-2938, 2005 | 119 | 2005 |
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM TET Hughes, DT Lodowski, KW Huynh, A Yazici, J Del Rosario, A Kapoor, ... Nature structural & molecular biology 25 (1), 53-60, 2018 | 117 | 2018 |
GPCRmd uncovers the dynamics of the 3D-GPCRome I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ... Nature Methods 17 (8), 777-787, 2020 | 115 | 2020 |
Opioid receptors: Structural and mechanistic insights into pharmacology and signaling Y Shang, M Filizola European journal of pharmacology 763, 206-213, 2015 | 115 | 2015 |
Assessing the relative stability of dimer interfaces in g protein-coupled receptors JM Johnston, H Wang, D Provasi, M Filizola Public Library of Science 8 (8), e1002649, 2012 | 113 | 2012 |
Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method M Filizola, O Olmea, H Weinstein Protein engineering 15 (11), 881-885, 2002 | 109 | 2002 |
Structural models for dimerization of G‐protein coupled receptors: The opioid receptor homodimers M Filizola, H Weinstein Peptide Science: Original Research on Biomolecules 66 (5), 317-325, 2002 | 107 | 2002 |