A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation S Pinter, F Knodel, M Choudalakis, P Schnee, C Kroll, M Fuchs, A Broehm, ... Nucleic Acids Research 49 (8), 4350-4370, 2021 | 16 | 2021 |
Preferential self-interaction of DNA methyltransferase DNMT3A subunits containing the R882H cancer mutation leads to dominant changes of flanking sequence preferences A Mack, M Emperle, P Schnee, S Adam, J Pleiss, P Bashtrykov, A Jeltsch Journal of molecular biology 434 (7), 167482, 2022 | 8 | 2022 |
Mechanistic basis of the increased methylation activity of the SETD2 protein lysine methyltransferase towards a designed super-substrate peptide P Schnee, M Choudalakis, S Weirich, MS Khella, H Carvalho, J Pleiss, ... Communications Chemistry 5 (1), 139, 2022 | 5 | 2022 |
The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation MS Khella, P Schnee, S Weirich, T Bui, A Bröhm, P Bashtrykov, J Pleiss, ... Journal of Biological Chemistry 299 (6), 2023 | 4 | 2023 |
Approaching the catalytic mechanism of protein lysine methyltransferases by biochemical and simulation techniques P Schnee, J Pleiss, A Jeltsch Critical Reviews in Biochemistry and Molecular Biology, 1-49, 2024 | 3 | 2024 |
Discovery of NSD2 non-histone substrates and design of a super-substrate S Weirich, D Kusevic, P Schnee, J Reiter, J Pleiss, A Jeltsch Communications Biology 7 (1), 707, 2024 | | 2024 |
Charakterisierung der Substratspezifität von Protein-Methyltransferasen P Schnee, S Weirich, A Jeltsch BIOspektrum 29 (3), 249-251, 2023 | | 2023 |