Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes AK Bentzen, AM Marquard, R Lyngaa, SK Saini, S Ramskov, M Donia, ... Nature biotechnology 34 (10), 1037-1045, 2016 | 352 | 2016 |
NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data A Montemurro, V Schuster, HR Povlsen, AK Bentzen, V Jurtz, ... Communications Biology 4 (1), 1-13, 2021 | 153 | 2021 |
General detection and isolation of specific cells by binding of labeled molecules H Pedersen, S Jakobsen, SR Hadrup, AK Bentzen, KH Johansen US Patent 11,585,806, 2023 | 122 | 2023 |
Determining antigen recognition through barcoding of mhc multimers SR Hadrup, H Pedersen, S Jakobsen, AK Bentzen | 106 | 2019 |
CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens NW Pedersen, A Holm, NP Kristensen, AM Bjerregaard, AK Bentzen, ... Nature communications 10 (1), 1-12, 2019 | 106 | 2019 |
T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide–MHC complexes AK Bentzen, L Such, KK Jensen, AM Marquard, LE Jessen, NJ Miller, ... Nature biotechnology 36 (12), 1191, 2018 | 98 | 2018 |
NetTCR: sequence-based prediction of TCR binding to peptide-MHC complexes using convolutional neural networks VI Jurtz, LE Jessen, AK Bentzen, MC Jespersen, S Mahajan, R Vita, ... bioRxiv, 433706, 2018 | 98 | 2018 |
Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma NP Kristensen, C Heeke, SA Tvingsholm, A Borch, A Draghi, ... The Journal of clinical investigation 132 (2), 2022 | 92 | 2022 |
Evolution of MHC-based technologies used for detection of antigen-responsive T cells AK Bentzen, SR Hadrup Cancer Immunology, Immunotherapy 66 (5), 657-666, 2017 | 85 | 2017 |
Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers SK Saini, AD Ørskov, AM Bjerregaard, A Unnikrishnan, ... Nature communications 11 (1), 1-14, 2020 | 71 | 2020 |
Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma JS Holm, SA Funt, A Borch, KK Munk, AM Bjerregaard, JL Reading, ... Nature Communications 13 (1), 1-17, 2022 | 60 | 2022 |
Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations UK Hansen, S Ramskov, AM Bjerregaard, A Borch, R Andersen, A Draghi, ... Frontiers in immunology 11, 373, 2020 | 36 | 2020 |
T-cell-receptor cross-recognition and strategies to select safe T-cell receptors for clinical translation AK Bentzen, SR Hadrup Immuno-Oncology Technology 2, 1-10, 2019 | 25 | 2019 |
T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients N Viborg, S Ramskov, RS Andersen, T Sturm, T Fugmann, AK Bentzen, ... OncoImmunology, 1663107, 2019 | 14 | 2019 |
Improved T cell receptor antigen pairing through data-driven filtering of sequencing information from single cells HR Povlsen, AK Bentzen, M Kadivar, LE Jessen, SR Hadrup, M Nielsen Elife 12, e81810, 2023 | 9 | 2023 |
AT cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo E Giannakopoulou, M Lehander, S Virding Culleton, W Yang, Y Li, ... Nature Cancer, 1-17, 2023 | 7 | 2023 |
TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy SA Tvingsholm, MS Frej, VM Rafa, UK Hansen, M Ormhøj, A Tyron, ... Journal for Immunotherapy of Cancer 11 (8), 2023 | 5 | 2023 |
Simultaneous analysis of pMHC binding and reactivity unveils virus-specific CD8 T cell immunity to a concise epitope set NP Kristensen, E Dionisio, AK Bentzen, T Tamhane, JS Kemming, G Nos, ... Science Advances 10 (15), eadm8951, 2024 | 2 | 2024 |
T antigen-specific CD8+ T cells associate with PD-1 blockade response in virus-positive Merkel cell carcinoma UK Hansen, CD Church, AMC Simões, MS Frej, AK Bentzen, ... The Journal of Clinical Investigation, 2024 | 1 | 2024 |
General detection and isolation of specific cells by binding of labeled molecules H Pedersen, S Jakobsen, SR Hadrup, AK Bentzen, KH Johansen US Patent 11,668,705, 2023 | 1 | 2023 |