A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets P Marchetti, R Lupi, M Bugliani, CL Kirkpatrick, G Sebastiani, FA Grieco, ... Diabetologia 55, 3262-3272, 2012 | 275 | 2012 |
Lymphocyte-derived exosomal microRNAs promote pancreatic β cell death and may contribute to type 1 diabetes development C Guay, JK Kruit, S Rome, V Menoud, NL Mulder, A Jurdzinski, ... Cell metabolism 29 (2), 348-361. e6, 2019 | 234 | 2019 |
Reduction of circulating neutrophils precedes and accompanies type 1 diabetes A Valle, GM Giamporcaro, M Scavini, A Stabilini, P Grogan, E Bianconi, ... Diabetes 62 (6), 2072-2077, 2013 | 224 | 2013 |
SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature D Fignani, G Licata, N Brusco, L Nigi, GE Grieco, L Marselli, L Overbergh, ... Frontiers in endocrinology 11, 596898, 2020 | 222 | 2020 |
Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors S Culina, AI Lalanne, G Afonso, K Cerosaletti, S Pinto, G Sebastiani, ... Science immunology 3 (20), eaao4013, 2018 | 202 | 2018 |
Conventional and neo-antigenic peptides presented by β cells are targeted by circulating naïve CD8+ T cells in type 1 diabetic and healthy donors S Gonzalez-Duque, ME Azoury, ML Colli, G Afonso, JV Turatsinze, L Nigi, ... Cell metabolism 28 (6), 946-960. e6, 2018 | 194 | 2018 |
Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice S Robert, C Gysemans, T Takiishi, H Korf, I Spagnuolo, G Sebastiani, ... Diabetes 63 (8), 2876-2887, 2014 | 180 | 2014 |
MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion G Sebastiani, A Po, E Miele, G Ventriglia, E Ceccarelli, M Bugliani, ... Acta Diabetologica 52, 523-530, 2015 | 152 | 2015 |
Increased expression of microRNA miR‐326 in type 1 diabetic patients with ongoing islet autoimmunity G Sebastiani, FA Grieco, I Spagnuolo, L Galleri, D Cataldo, F Dotta Diabetes/metabolism research and reviews 27 (8), 862-866, 2011 | 148 | 2011 |
MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p regulate the expression of proapoptotic BH3-only proteins DP5 and PUMA in human pancreatic β-cells FA Grieco, G Sebastiani, J Juan-Mateu, O Villate, L Marroqui, L Ladrière, ... Diabetes 66 (1), 100-112, 2017 | 109 | 2017 |
Circulating microRNAs and diabetes mellitus: a novel tool for disease prediction, diagnosis, and staging? G Sebastiani, L Nigi, GE Grieco, F Mancarella, G Ventriglia, F Dotta Journal of endocrinological investigation 40, 591-610, 2017 | 105 | 2017 |
MicroRNAs as regulators of insulin signaling: research updates and potential therapeutic perspectives in type 2 diabetes L Nigi, GE Grieco, G Ventriglia, N Brusco, F Mancarella, C Formichi, ... International journal of molecular sciences 19 (12), 3705, 2018 | 102 | 2018 |
Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes F Vecchio, NL Buono, A Stabilini, L Nigi, MJ Dufort, S Geyer, PM Rancoita, ... JCI insight 3 (18), 2018 | 99 | 2018 |
Dietary supplementation with high doses of regular vitamin D3 safely reduces diabetes incidence in NOD mice when given early and long term T Takiishi, L Ding, F Baeke, I Spagnuolo, G Sebastiani, J Laureys, ... Diabetes 63 (6), 2026-2036, 2014 | 97 | 2014 |
Circulating microRNA (miRNA) expression profiling in plasma of patients with gestational diabetes mellitus reveals upregulation of miRNA miR-330-3p G Sebastiani, E Guarino, GE Grieco, C Formichi, C Delli Poggi, ... Frontiers in endocrinology 8, 345, 2017 | 96 | 2017 |
Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells E Ifie, MA Russell, S Dhayal, P Leete, G Sebastiani, L Nigi, F Dotta, ... Diabetologia 61, 2344-2355, 2018 | 77 | 2018 |
Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the … T Takiishi, DP Cook, H Korf, G Sebastiani, F Mancarella, JPMCM Cunha, ... Diabetes 66 (2), 448-459, 2017 | 76 | 2017 |
Circulating microRNAs as biomarkers of Gestational Diabetes Mellitus: updates and perspectives E Guarino, CD Poggi, GE Grieco, V Cenci, E Ceccarelli, I Crisci, ... | 75 | 2018 |
Dapagliflozin modulates glucagon secretion in an SGLT2-independent manner in murine alpha cells A Solini, G Sebastiani, L Nigi, E Santini, C Rossi, F Dotta Diabetes & metabolism 43 (6), 512-520, 2017 | 72 | 2017 |
Circulating miRNA95 and miRNA190 are sensitive markers for the differential diagnosis of thyroid nodules in a Caucasian population S Cantara, T Pilli, G Sebastiani, G Cevenini, G Busonero, S Cardinale, ... The Journal of Clinical Endocrinology & Metabolism 99 (11), 4190-4198, 2014 | 66 | 2014 |