Kif15 cooperates with eg5 to promote bipolar spindle assembly ME Tanenbaum, L Macůrek, A Janssen, EF Geers, M Alvarez-Fernández, ... Current biology 19 (20), 1703-1711, 2009 | 312 | 2009 |
Activation of nuclear factor-kappa B signalling promotes cellular senescence E Rovillain, L Mansfield, C Caetano, M Alvarez-Fernandez, OL Caballero, ... Oncogene 30 (20), 2356-2366, 2011 | 230 | 2011 |
Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain J Laoukili, M Alvarez, LAT Meijer, M Stahl, S Mohammed, L Kleij, ... Molecular and cellular biology 28 (9), 3076-3087, 2008 | 195 | 2008 |
DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly M Álvarez, X Estivill, S de la Luna Journal of cell science 116 (15), 3099-3107, 2003 | 178 | 2003 |
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system E Martı́, X Altafaj, M Dierssen, S de la Luna, V Fotaki, M Alvarez, ... Brain research 964 (2), 250-263, 2003 | 168 | 2003 |
Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence DR Littler, M Alvarez-Fernández, A Stein, RG Hibbert, T Heidebrecht, ... Nucleic Acids Research 38 (13), 4527-4538, 2010 | 156 | 2010 |
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy. R Sánchez-Martínez, S Cruz-Gil, CM Gómez, M Álvarez-Fernández, ... Oncotarget, 2015 | 148 | 2015 |
Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals M Álvarez-Fernández, R Sánchez-Martínez, B Sanz-Castillo, PP Gan, ... Proceedings of the National Academy of Sciences 110 (43), 17374-17379, 2013 | 116 | 2013 |
FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner J Laoukili, M Alvarez-Fernandez, M Stahl, RH Medema Cell Cycle 7 (17), 2720-2726, 2008 | 116 | 2008 |
DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding M Alvarez, X Altafaj, S Aranda, S De La Luna Molecular biology of the cell 18 (4), 1167-1178, 2007 | 97 | 2007 |
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer M Álvarez-Fernández, M Sanz-Flores, B Sanz-Castillo, M Salazar-Roa, ... Cell Death & Differentiation, 1, 2017 | 92 | 2017 |
Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A S Aranda, M Alvarez, S Turró, A Laguna, S de la Luna Molecular and cellular biology 28 (19), 5899-5911, 2008 | 90 | 2008 |
Novel functions of FoxM1: from molecular mechanisms to cancer therapy M Alvarez-Fernández, RH Medema Frontiers in Oncology 3, 30, 2013 | 88 | 2013 |
Two interlinked bistable switches govern mitotic control in mammalian cells S Rata, MFSP Rodriguez, S Joseph, N Peter, FE Iturra, F Yang, ... Current Biology, 2018 | 76 | 2018 |
Missense mutations in the cystic fibrosis gene in adult patients with asthma C Lazaro, R de Cid, J Sunyer, J Soriano, J Giménez, M Alvarez, T Casals, ... Human mutation 14 (6), 510-519, 1999 | 71 | 1999 |
Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1 M Alvarez-Fernández, VA Halim, L Krenning, M Aprelia, S Mohammed, ... EMBO reports 11 (6), 452-458, 2010 | 66 | 2010 |
A Synthetic Lethal Interaction between APC/C and Topoisomerase Poisons Uncovered by Proteomic Screens M Eguren, M Álvarez-Fernández, F García, AJ López-Contreras, ... Cell reports 6 (4), 670-683, 2014 | 54 | 2014 |
An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability J Mitxelena, A Apraiz, J Vallejo-Rodríguez, I García-Santisteban, ... Nucleic acids research, 2018 | 46 | 2018 |
Protein Phosphatase 2A (B55α) Prevents Premature Activation of Forkhead Transcription Factor FoxM1 by Antagonizing Cyclin A/Cyclin-dependent Kinase-mediated Phosphorylation M Alvarez-Fernández, VA Halim, M Aprelia, S Mohammed, RH Medema Journal of Biological Chemistry 286 (38), 33029-33036, 2011 | 46 | 2011 |
Preparing a cell for nuclear envelope breakdown: Spatio‐temporal control of phosphorylation during mitotic entry M Álvarez‐Fernández, M Malumbres BioEssays, 2014 | 32 | 2014 |