The developability classification system: application of biopharmaceutics concepts to formulation development JM Butler, JB Dressman Journal of pharmaceutical sciences 99 (12), 4940-4954, 2010 | 477 | 2010 |
Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds M Vertzoni, J Dressman, J Butler, J Hempenstall, C Reppas European Journal of Pharmaceutics and Biopharmaceutics 60 (3), 413-417, 2005 | 471 | 2005 |
In vitro models for the prediction of in vivo performance of oral dosage forms ES Kostewicz, B Abrahamsson, M Brewster, J Brouwers, J Butler, ... European Journal of Pharmaceutical Sciences 57, 342-366, 2014 | 409 | 2014 |
Precipitation in and supersaturation of contents of the upper small intestine after administration of two weak bases to fasted adults D Psachoulias, M Vertzoni, K Goumas, V Kalioras, S Beato, J Butler, ... Pharmaceutical research 28, 3145-3158, 2011 | 229 | 2011 |
Preparation of glass solutions of three poorly water soluble drugs by spray drying, melt extrusion and ball milling JE Patterson, MB James, AH Forster, RW Lancaster, JM Butler, T Rades International journal of pharmaceutics 336 (1), 22-34, 2007 | 226 | 2007 |
A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption P Augustijns, B Wuyts, B Hens, P Annaert, J Butler, J Brouwers European Journal of Pharmaceutical Sciences 57, 322-332, 2014 | 204 | 2014 |
The influence of thermal and mechanical preparative techniques on the amorphous state of four poorly soluble compounds JE Patterson, MB James, AH Forster, RW Lancaster, JM Butler, T Rades Journal of pharmaceutical sciences 94 (9), 1998-2012, 2005 | 175 | 2005 |
The BCS: where do we go from here? J Dressman, J Butler, J Hempenstall, C Reppas Pharmaceutical Technology 25 (7), 68-68, 2001 | 172 | 2001 |
Media to simulate the postprandial stomach I. Matching the physicochemical characteristics of standard breakfasts S Klein, JB Dressman, J Butler, JM Hempenstall, C Reppas Journal of pharmacy and pharmacology 56 (5), 605-610, 2004 | 146 | 2004 |
Oral biopharmaceutics tools–time for a new initiative–an introduction to the IMI project OrBiTo H Lennernäs, L Aarons, P Augustijns, S Beato, M Bolger, K Box, ... European Journal of Pharmaceutical Sciences 57, 292-299, 2014 | 133 | 2014 |
In vitro models for the prediction of in vivo performance of oral dosage forms: recent progress from partnership through the IMI OrBiTo collaboration J Butler, B Hens, M Vertzoni, J Brouwers, P Berben, J Dressman, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 70-83, 2019 | 122 | 2019 |
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network Z Vinarov, B Abrahamsson, P Artursson, H Batchelor, P Berben, ... Advanced Drug Delivery Reviews 171, 289-331, 2021 | 104 | 2021 |
Quality guidelines for oral drug candidates: dose, solubility and lipophilicity MK Bayliss, J Butler, PL Feldman, DVS Green, PD Leeson, MR Palovich, ... Drug Discovery Today 21 (10), 1719-1727, 2016 | 101 | 2016 |
An In Vitro Methodology for Forecasting Luminal Concentrations and Precipitation of Highly Permeable Lipophilic Weak Bases in the Fasted Upper Small Intestine D Psachoulias, M Vertzoni, J Butler, D Busby, M Symillides, J Dressman, ... Pharmaceutical research 29, 3486-3498, 2012 | 99 | 2012 |
Validation of dissolution testing with biorelevant media: an OrBiTo study J Mann, J Dressman, K Rosenblatt, L Ashworth, U Muenster, K Frank, ... Molecular pharmaceutics 14 (12), 4192-4201, 2017 | 93 | 2017 |
A comparative study of different release apparatus in generating in vitro–in vivo correlations for extended release formulations N Fotaki, A Aivaliotis, J Butler, J Dressman, M Fischbach, J Hempenstall, ... European journal of pharmaceutics and biopharmaceutics 73 (1), 115-120, 2009 | 92 | 2009 |
Predicting the human in vivo performance of different oral capsule shell types using a novel in vitro dynamic gastric model M Vardakou, A Mercuri, TA Naylor, D Rizzo, JM Butler, PC Connolly, ... International journal of pharmaceutics 419 (1-2), 192-199, 2011 | 80 | 2011 |
A refined developability classification system J Rosenberger, J Butler, J Dressman Journal of pharmaceutical sciences 107 (8), 2020-2032, 2018 | 79 | 2018 |
MRI studies of the hydrodynamics in a USP 4 dissolution testing cell G Shiko, LF Gladden, AJ Sederman, PC Connolly, JM Butler Journal of pharmaceutical sciences 100 (3), 976-991, 2011 | 53 | 2011 |
Factors affecting incorporation of drug into solid solution with HPMCP during solvent change co-precipitation G Sertsou, J Butler, A Scott, J Hempenstall, T Rades International journal of pharmaceutics 245 (1-2), 99-108, 2002 | 53 | 2002 |