Recent functional insights into the role of (p) ppGpp in bacterial physiology V Hauryliuk, GC Atkinson, KS Murakami, T Tenson, K Gerdes Nature Reviews Microbiology 13 (5), 298-309, 2015 | 850 | 2015 |
The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life GC Atkinson, T Tenson, V Hauryliuk PloS one 6 (8), e23479, 2011 | 475 | 2011 |
Single-molecule investigations of the stringent response machinery in living bacterial cells BP English, V Hauryliuk, A Sanamrad, S Tankov, NH Dekker, J Elf Proceedings of the National Academy of Sciences 108 (31), E365-E373, 2011 | 316 | 2011 |
Reassessing the role of type II toxin-antitoxin systems in formation of Escherichia coli type II persister cells F Goormaghtigh, N Fraikin, M Putrinš, T Hallaert, V Hauryliuk, ... MBio 9 (3), 10.1128/mbio. 00640-18, 2018 | 210 | 2018 |
Splitting of the posttermination ribosome into subunits by the concerted action of RRF and EF-G AV Zavialov, VV Hauryliuk, M Ehrenberg Molecular cell 18 (6), 675-686, 2005 | 182 | 2005 |
Mechanism of tetracycline resistance by ribosomal protection protein Tet (O) W Li, GC Atkinson, NS Thakor, Ü Allas, C Lu, KY Chan, T Tenson, ... Nature communications 4 (1), 1477, 2013 | 158 | 2013 |
Target protection as a key antibiotic resistance mechanism DN Wilson, V Hauryliuk, GC Atkinson, AJ O’Neill Nature Reviews Microbiology 18 (11), 637-648, 2020 | 146 | 2020 |
Structure of the Dom34–Hbs1 complex and implications for no-go decay L Chen, D Muhlrad, V Hauryliuk, Z Cheng, MK Lim, V Shyp, R Parker, ... Nature structural & molecular biology 17 (10), 1233-1240, 2010 | 138 | 2010 |
The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis S Arenz, M Abdelshahid, D Sohmen, R Payoe, AL Starosta, ... Nucleic acids research 44 (13), 6471-6481, 2016 | 137 | 2016 |
Evolution of nonstop, no-go and nonsense-mediated mRNA decay and their termination factor-derived components GC Atkinson, SL Baldauf, V Hauryliuk BMC evolutionary biology 8, 1-18, 2008 | 137 | 2008 |
Positive allosteric feedback regulation of the stringent response enzyme RelA by its product V Shyp, S Tankov, A Ermakov, P Kudrin, BP English, M Ehrenberg, ... EMBO reports 13 (9), 835-839, 2012 | 125 | 2012 |
Persisters—as elusive as ever N Kaldalu, V Hauryliuk, T Tenson Applied microbiology and biotechnology 100 (15), 6545-6553, 2016 | 122 | 2016 |
ABCF ATPases involved in protein synthesis, ribosome assembly and antibiotic resistance: structural and functional diversification across the tree of life V Murina, M Kasari, H Takada, M Hinnu, CK Saha, JW Grimshaw, T Seki, ... Journal of molecular biology 431 (18), 3568-3590, 2019 | 113 | 2019 |
From (p) ppGpp to (pp) pGpp: characterization of regulatory effects of pGpp synthesized by the small alarmone synthetase of Enterococcus faecalis AO Gaca, P Kudrin, C Colomer-Winter, J Beljantseva, K Liu, B Anderson, ... Journal of bacteriology 197 (18), 2908-2919, 2015 | 104 | 2015 |
HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp V Varik, SRA Oliveira, V Hauryliuk, T Tenson Scientific reports 7 (1), 11022, 2017 | 102 | 2017 |
Thermodynamic characterization of ppGpp binding to EF-G or IF2 and of initiator tRNA binding to free IF2 in the presence of GDP, GTP, or ppGpp VA Mitkevich, A Ermakov, AA Kulikova, S Tankov, V Shyp, A Soosaar, ... Journal of molecular biology 402 (5), 838-846, 2010 | 102 | 2010 |
A widespread toxin− antitoxin system exploiting growth control via alarmone signaling S Jimmy, CK Saha, T Kurata, C Stavropoulos, SRA Oliveira, A Koh, ... Proceedings of the National Academy of Sciences 117 (19), 10500-10510, 2020 | 100 | 2020 |
Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR C Crowe-McAuliffe, M Graf, P Huter, H Takada, M Abdelshahid, ... Proceedings of the National Academy of Sciences 115 (36), 8978-8983, 2018 | 97 | 2018 |
Direct activation of a bacterial innate immune system by a viral capsid protein T Zhang, H Tamman, K Coppieters’t Wallant, T Kurata, M LeRoux, ... Nature 612 (7938), 132-140, 2022 | 85 | 2022 |
Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs AV Zavialov, VV Hauryliuk, M Ehrenberg Journal of biology 4, 9, 2005 | 85 | 2005 |