| Lupin peptides modulate the protein-protein interaction of PCSK9 with the low density lipoprotein receptor in HepG2 cells C Lammi, C Zanoni, G Aiello, A Arnoldi, G Grazioso Scientific reports 6 (1), 29931, 2016 | 84 | 2016 |
| Investigating the Mechanism of Substrate Uptake and Release in the Glutamate Transporter Homologue GltPh through Metadynamics Simulations G Grazioso, V Limongelli, D Branduardi, E Novellino, C De Micheli, ... Journal of the American Chemical Society 134 (1), 453-463, 2012 | 74 | 2012 |
| Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor F Mazzo, F Pistillo, G Grazioso, F Clementi, N Borgese, C Gotti, ... Journal of Neuroscience 33 (30), 12316-12328, 2013 | 61 | 2013 |
| Synthesis, binding affinity at glutamic acid receptors, neuroprotective effects, and molecular modeling investigation of novel dihydroisoxazole amino acids P Conti, M De Amici, G Grazioso, G Roda, A Pinto, KB Hansen, B Nielsen, ... Journal of medicinal chemistry 48 (20), 6315-6325, 2005 | 57 | 2005 |
| Synthesis, chiral resolution, and enantiopharmacology of a potent 2, 3-benzodiazepine derivative as noncompetitive AMPA receptor antagonist M Zappala, G Postorino, N Micale, S Caccamese, N Parrinello, ... Journal of medicinal chemistry 49 (2), 575-581, 2006 | 50 | 2006 |
| Disrupting the PCSK9/LDLR protein–protein interaction by an imidazole-based minimalist peptidomimetic M Stucchi, G Grazioso, C Lammi, S Manara, C Zanoni, A Arnoldi, ... Organic & Biomolecular Chemistry 14 (41), 9736-9740, 2016 | 44 | 2016 |
| Alpha7 nicotinic acetylcholine receptor agonists: prediction of their binding affinity through a Molecular Mechanics Poisson–Boltzmann Surface Area approach G Grazioso, A Cavalli, M De Amici, M Recanatini, C De Micheli Journal of computational chemistry 29 (15), 2593-2602, 2008 | 43 | 2008 |
| Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer A Spinello, S Martini, F Berti, M Pennati, M Pavlin, J Sgrignani, G Grazioso, ... European journal of medicinal chemistry 168, 253-262, 2019 | 42 | 2019 |
| Engineering of α‐conotoxin MII‐derived peptides with increased selectivity for native α6β2∗ nicotinic acetylcholine receptors L Pucci, G Grazioso, C Dallanoce, L Rizzi, C De Micheli, F Clementi, ... The FASEB Journal 25 (11), 3775-3789, 2011 | 42 | 2011 |
| Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl‐Δ2‐Isoxazoline Derivatives as Potent and Selective Agonists of α7 … C Dallanoce, P Magrone, C Matera, F Frigerio, G Grazioso, M De Amici, ... ChemMedChem 6 (5), 889-903, 2011 | 41 | 2011 |
| Determination of acid dissociation constants of compounds active at neuronal nicotinic acetylcholine receptors by means of electrophoretic and potentiometric techniques G Roda, C Dallanoce, G Grazioso, V Liberti, M De Amici Analytical Sciences 26 (1), 51-54, 2010 | 39 | 2010 |
| Inactivation of TEM-1 by avibactam (NXL-104): insights from quantum mechanics/molecular mechanics metadynamics simulations J Sgrignani, G Grazioso, M De Amici, G Colombo Biochemistry 53 (31), 5174-5185, 2014 | 38 | 2014 |
| Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors R Ettari, M Zappalà, N Micale, G Grazioso, S Giofrè, T Schirmeister, ... European journal of medicinal chemistry 46 (6), 2058-2065, 2011 | 38 | 2011 |
| The response of Escherichia coli biofilm to salicylic acid C Cattò, G Grazioso, S Dell’Orto, A Gelain, S Villa, V Marzano, A Vitali, ... Biofouling 33 (3), 235-251, 2017 | 36 | 2017 |
| Mechanism of falcipain-2 inhibition by α, β-unsaturated benzo [1, 4] diazepin-2-one methyl ester G Grazioso, L Legnani, L Toma, R Ettari, N Micale, C De Micheli Journal of computer-aided molecular design 26, 1035-1043, 2012 | 33 | 2012 |
| Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain‐2 inhibitors R Ettari, N Micale, G Grazioso, F Bova, T Schirmeister, S Grasso, ... ChemMedChem 7 (9), 1594-1600, 2012 | 33 | 2012 |
| Computationally driven structure optimization, synthesis, and biological evaluation of imidazole-based proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors C Lammi, J Sgrignani, A Arnoldi, G Lesma, C Spatti, A Silvani, G Grazioso Journal of medicinal chemistry 62 (13), 6163-6174, 2019 | 32 | 2019 |
| Design of novel α7-subtype-preferring nicotinic acetylcholine receptor agonists: Application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies G Grazioso, DY Pomè, C Matera, F Frigerio, L Pucci, C Gotti, C Dallanoce, ... Bioorganic & medicinal chemistry letters 19 (22), 6353-6357, 2009 | 32 | 2009 |
| Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters A Pinto, P Conti, M De Amici, L Tamborini, G Grazioso, S Colleoni, ... Tetrahedron: Asymmetry 19 (7), 867-875, 2008 | 31 | 2008 |
| Application of the Ugi reaction with multiple amino acid-derived components: Synthesis and conformational evaluation of piperazine-based minimalist peptidomimetics M Stucchi, S Cairati, R Cetin-Atalay, MS Christodoulou, G Grazioso, ... Organic & biomolecular chemistry 13 (17), 4993-5005, 2015 | 30 | 2015 |
