Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans M Hirano, K Maeda, Y Shitara, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 311 (1), 139-146, 2004 | 522 | 2004 |
Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption Y Shitara, K Maeda, K Ikejiri, K Yoshida, T Horie, Y Sugiyama Biopharmaceutics & drug disposition 34 (1), 45-78, 2013 | 434 | 2013 |
Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans T Watanabe, H Kusuhara, K Maeda, Y Shitara, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 328 (2), 652-662, 2009 | 393 | 2009 |
Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin S Kitamura, K Maeda, Y Wang, Y Sugiyama Drug Metabolism and Disposition 36 (10), 2014-2023, 2008 | 393 | 2008 |
Drug-drug interaction between pitavastatin and various drugs via OATP1B1 M Hirano, K Maeda, Y Shitara, Y Sugiyama Drug metabolism and disposition 34 (7), 1229-1236, 2006 | 349 | 2006 |
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin M Hirano, K Maeda, S Matsushima, Y Nozaki, H Kusuhara, Y Sugiyama Molecular pharmacology 68 (3), 800-807, 2005 | 314 | 2005 |
Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting … S Matsushima, K Maeda, C Kondo, M Hirano, M Sasaki, H Suzuki, ... Journal of Pharmacology and Experimental Therapeutics 314 (3), 1059-1067, 2005 | 239 | 2005 |
Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans W Yamashiro, K Maeda, M Hirouchi, Y Adachi, Z Hu, Y Sugiyama Drug metabolism and disposition 34 (7), 1247-1254, 2006 | 235 | 2006 |
Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril K Maeda, I Ieiri, K Yasuda, A Fujino, H Fujiwara, K Otsubo, M Hirano, ... Clinical Pharmacology & Therapeutics 79 (5), 427-439, 2006 | 233 | 2006 |
Investigation of the rate-determining process in the hepatic elimination of HMG-CoA reductase inhibitors in rats and humans T Watanabe, H Kusuhara, K Maeda, H Kanamaru, Y Saito, Z Hu, ... Drug Metabolism and Disposition 38 (2), 215-222, 2010 | 228 | 2010 |
Identification of the rate‐determining process in the hepatic clearance of atorvastatin in a clinical cassette microdosing study K Maeda, Y Ikeda, T Fujita, K Yoshida, Y Azuma, Y Haruyama, N Yamane, ... Clinical Pharmacology & Therapeutics 90 (4), 575-581, 2011 | 219 | 2011 |
Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin M Hirano, K Maeda, H Hayashi, H Kusuhara, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 314 (2), 876-882, 2005 | 215 | 2005 |
Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans M Shimizu, K Fuse, K Okudaira, R Nishigaki, K Maeda, H Kusuhara, ... Drug Metabolism and Disposition 33 (10), 1477-1481, 2005 | 205 | 2005 |
Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans N Ishiguro, K Maeda, W Kishimoto, A Saito, A Harada, T Ebner, W Roth, ... Drug metabolism and disposition 34 (7), 1109-1115, 2006 | 204 | 2006 |
Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs K Maeda, Y Sugiyama Drug metabolism and pharmacokinetics 23 (4), 223-235, 2008 | 198 | 2008 |
SLCO1B1 (OATP1B1, an Uptake Transporter) and ABCG2 (BCRP, an Efflux Transporter) Variant Alleles and Pharmacokinetics of Pitavastatin in Healthy Volunteers I Ieiri, S Suwannakul, K Maeda, H Uchimaru, K Hashimoto, M Kimura, ... Clinical Pharmacology & Therapeutics 82 (5), 541-547, 2007 | 189 | 2007 |
Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor A Yamada, K Maeda, E Kamiyama, D Sugiyama, T Kondo, Y Shiroyanagi, ... Drug metabolism and disposition 35 (12), 2166-2176, 2007 | 166 | 2007 |
Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP H Kusuhara, H Furuie, A Inano, A Sunagawa, S Yamada, C Wu, ... British journal of pharmacology 166 (6), 1793-1803, 2012 | 165 | 2012 |
Transporter‐Mediated Drug–Drug Interactions Involving OATP Substrates: Predictions Based on In Vitro Inhibition Studies K Yoshida, K Maeda, Y Sugiyama Clinical Pharmacology & Therapeutics 91 (6), 1053-1064, 2012 | 157 | 2012 |
Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions S Izumi, Y Nozaki, K Maeda, T Komori, O Takenaka, H Kusuhara, ... Drug Metabolism and Disposition 43 (2), 235-247, 2015 | 154 | 2015 |