Pan-cancer image-based detection of clinically actionable genetic alterations JN Kather, LR Heij, HI Grabsch, C Loeffler, A Echle, HS Muti, J Krause, ... Nature cancer 1 (8), 789-799, 2020 | 437 | 2020 |
Clinical-grade detection of microsatellite instability in colorectal tumors by deep learning A Echle, HI Grabsch, P Quirke, PA van den Brandt, NP West, ... Gastroenterology 159 (4), 1406-1416. e11, 2020 | 246 | 2020 |
The impact of site-specific digital histology signatures on deep learning model accuracy and bias FM Howard, J Dolezal, S Kochanny, J Schulte, H Chen, L Heij, D Huo, ... Nature communications 12 (1), 4423, 2021 | 175 | 2021 |
Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study L Heij, M Niesters, M Swartjes, E Hoitsma, M Drent, A Dunne, JC Grutters, ... Molecular medicine 18, 1430-1436, 2012 | 109 | 2012 |
ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density A Dahan, A Dunne, M Swartjes, PL Proto, L Heij, O Vogels, M van Velzen, ... Molecular medicine 19, 334-345, 2013 | 99 | 2013 |
Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort … HS Muti, LR Heij, G Keller, M Kohlruss, R Langer, B Dislich, JH Cheong, ... The Lancet Digital Health 3 (10), e654-e664, 2021 | 86 | 2021 |
Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma X Tan, S Sivakumar, J Bednarsch, G Wiltberger, JN Kather, J Niehues, ... Oncogene 40 (5), 899-908, 2021 | 69 | 2021 |
Weakly supervised annotation‐free cancer detection and prediction of genotype in routine histopathology PL Schrammen, N Ghaffari Laleh, A Echle, D Truhn, V Schulz, TJ Brinker, ... The Journal of pathology 256 (1), 50-60, 2022 | 64 | 2022 |
The role of tumor-infiltrating lymphocytes in cholangiocarcinoma D Liu, LR Heij, Z Czigany, E Dahl, SA Lang, TF Ulmer, T Luedde, ... Journal of Experimental & Clinical Cancer Research 41 (1), 127, 2022 | 55 | 2022 |
Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer S Brockmoeller, A Echle, N Ghaffari Laleh, S Eiholm, ML Malmstrøm, ... The Journal of pathology 256 (3), 269-281, 2022 | 48 | 2022 |
Sarcoidosis and pain caused by small‐fiber neuropathy L Heij, A Dahan, E Hoitsma Pain Research and Treatment 2012 (1), 256024, 2012 | 47 | 2012 |
Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes I de Santiago, C Yau, L Heij, MR Middleton, F Markowetz, HI Grabsch, ... International journal of cancer 145 (4), 1125-1137, 2019 | 45 | 2019 |
ARA 290 for treatment of small fiber neuropathy in sarcoidosis M van Velzen, L Heij, M Niesters, A Cerami, A Dunne, A Dahan, M Brines Expert opinion on investigational drugs 23 (4), 541-550, 2014 | 40 | 2014 |
Activated regulatory T-cells, dysfunctional and senescent T-cells hinder the immunity in pancreatic cancer S Sivakumar, E Abu-Shah, DJ Ahern, EH Arbe-Barnes, AK Jainarayanan, ... Cancers 13 (8), 1776, 2021 | 36 | 2021 |
Quality of life in sarcoidosis MA Judson Seminars in respiratory and critical care medicine 38 (04), 546-558, 2017 | 34 | 2017 |
Generation and initial characterization of novel tumour organoid models to study human pancreatic cancer‐induced cachexia RDW Vaes, DPJ van Dijk, TTJ Welbers, MJ Blok, MR Aberle, L Heij, ... Journal of cachexia, sarcopenia and muscle 11 (6), 1509-1524, 2020 | 33 | 2020 |
Nationwide treatment and outcomes of perihilar cholangiocarcinoma AM van Keulen, S Franssen, LG van der Geest, MT de Boer, M Coenraad, ... Liver International 41 (8), 1945-1953, 2021 | 31 | 2021 |
Sublethal necroptosis signaling promotes inflammation and liver cancer M Vucur, A Ghallab, AT Schneider, A Adili, M Cheng, M Castoldi, ... Immunity 56 (7), 1578-1595. e8, 2023 | 30 | 2023 |
The role of sarcopenia and myosteatosis in short-and long-term outcomes following curative-intent surgery for hepatocellular carcinoma in a European cohort FA Meister, G Lurje, S Verhoeven, G Wiltberger, L Heij, WJ Liu, D Jiang, ... Cancers 14 (3), 720, 2022 | 27 | 2022 |
The erythropoietin analog ARA 290 for treatment of sarcoidosis-induced chronic neuropathic pain M Niesters, M Swartjes, L Heij, M Brines, A Cerami, A Dunne, E Hoitsma, ... Expert Opinion on Orphan Drugs 1 (1), 77-87, 2013 | 26 | 2013 |