Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies DT Rodgers, M Mazagova, EN Hampton, Y Cao, NS Ramadoss, IR Hardy, ... Proceedings of the National Academy of Sciences 113 (4), E459-E468, 2016 | 427 | 2016 |
Versatile strategy for controlling the specificity and activity of engineered T cells JSY Ma, JY Kim, SA Kazane, S Choi, HY Yun, MS Kim, DT Rodgers, ... Proceedings of the National Academy of Sciences 113 (4), E450-E458, 2016 | 304 | 2016 |
Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma D Raj, MH Yang, D Rodgers, EN Hampton, J Begum, A Mustafa, D Lorizio, ... Gut 68 (6), 1052-1064, 2019 | 137 | 2019 |
Design of switchable chimeric antigen receptor T cells targeting breast cancer Y Cao, DT Rodgers, J Du, I Ahmad, EN Hampton, JSY Ma, M Mazagova, ... Angewandte Chemie International Edition 55 (26), 7520-7524, 2016 | 123 | 2016 |
Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents … L Al-Riyami, MA Pineda, J Rzepecka, JK Huggan, AI Khalaf, CJ Suckling, ... Journal of medicinal chemistry 56 (24), 9982-10002, 2013 | 106 | 2013 |
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated … J Rzepecka, MA Pineda, L Al-Riyami, DT Rodgers, JK Huggan, FE Lumb, ... Journal of autoimmunity 60, 59-73, 2015 | 86 | 2015 |
An anti-B cell maturation antigen bispecific antibody for multiple myeloma NS Ramadoss, AD Schulman, S Choi, DT Rodgers, SA Kazane, CH Kim, ... Journal of the American Chemical Society 137 (16), 5288-5291, 2015 | 78 | 2015 |
Development of a chimeric antigen receptor targeting C-type lectin-like molecule-1 for human acute myeloid leukemia E Laborda, M Mazagova, S Shao, X Wang, H Quirino, AK Woods, ... International journal of molecular sciences 18 (11), 2259, 2017 | 75 | 2017 |
ES‐62 protects against collagen‐induced arthritis by resetting interleukin‐22 toward resolution of inflammation in the joints MA Pineda, DT Rodgers, L Al‐Riyami, W Harnett, MM Harnett Arthritis & rheumatology 66 (6), 1492-1503, 2014 | 69 | 2014 |
The parasitic worm product ES‐62 targets myeloid differentiation factor 88–dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr Mice DT Rodgers, MA McGrath, MA Pineda, L Al‐Riyami, J Rzepecka, F Lumb, ... Arthritis & Rheumatology 67 (4), 1023-1035, 2015 | 60 | 2015 |
Protection against collagen‐induced arthritis in mice afforded by the parasitic worm product, ES‐62, is associated with restoration of the levels of interleukin‐10‐producing B … DT Rodgers, MA Pineda, MA McGrath, L Al‐Riyami, W Harnett, ... Immunology 141 (3), 457-466, 2014 | 57 | 2014 |
Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody–drug conjugate S Yu, AD Pearson, RKV Lim, DT Rodgers, S Li, HB Parker, M Weglarz, ... Molecular Therapy 24 (12), 2078-2089, 2016 | 52 | 2016 |
The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma JC Coltherd, DT Rodgers, RE Lawrie, L Al-Riyami, CJ Suckling, W Harnett, ... Scientific reports 6 (1), 19224, 2016 | 47 | 2016 |
Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus DT Rodgers, MA Pineda, CJ Suckling, W Harnett, MM Harnett Lupus 24 (13), 1437-1442, 2015 | 43 | 2015 |
The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ RJ Eason, KS Bell, FA Marshall, DT Rodgers, MA Pineda, CN Steiger, ... Scientific Reports 6 (1), 37276, 2016 | 26 | 2016 |
Identification of a Novel Response Regulator, Crr1, That Is Required for Hydrogen Peroxide Resistance in Candida albicans CR Bruce, DA Smith, D Rodgers, A da Silva Dantas, DM MacCallum, ... PloS one 6 (12), e27979, 2011 | 19 | 2011 |
Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation L Al-Riyami, DT Rodgers, J Rzepecka, MA Pineda, CJ Suckling, ... Experimental parasitology 158, 18-22, 2015 | 17 | 2015 |
Testing small molecule analogues of the Acanthocheilonema viteae immunomodulator ES‐62 against clinically relevant allergens L Janicova, J Rzepecka, DT Rodgers, J Doonan, KS Bell, FE Lumb, ... Parasite immunology 38 (6), 340-351, 2016 | 11 | 2016 |
The parasitic worm product, ES-62 targets MyD88-dependent effector mechanisms to suppress ANA production and proteinuria in MRL/Lpr mice DT Rodgers, MA McGrath, MA Pineda, L Al-Riyami, J Rzepecka, F Lumb, ... Arthritis and Rheumatology 67 (4), 1023-1035, 2015 | 5 | 2015 |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof TS Young, L Presta, D Rodgers, E Hampton, T Wright, PG Schultz, ... US Patent 11,174,306, 2021 | 3 | 2021 |