Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2535 | 2020 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 469 | 2021 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 348 | 2021 |
An immune-based biomarker signature is associated with mortality in COVID-19 patients MS Abers, OM Delmonte, EE Ricotta, J Fintzi, DL Fink, AAA de Jesus, ... JCI insight 6 (1), 2021 | 332 | 2021 |
A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP G Lanzi, D Moratto, D Vairo, S Masneri, O Delmonte, T Paganini, ... Journal of Experimental Medicine 209 (1), 29-34, 2012 | 204 | 2012 |
Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19 K Sacco, R Castagnoli, S Vakkilainen, C Liu, OM Delmonte, C Oguz, ... Nature medicine 28 (5), 1050-1062, 2022 | 192 | 2022 |
Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19 C Liu, AJ Martins, WW Lau, N Rachmaninoff, J Chen, L Imberti, ... Cell 184 (7), 1836-1857. e22, 2021 | 191 | 2021 |
Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels TM Snyder, RM Gittelman, M Klinger, DH May, EJ Osborne, R Taniguchi, ... MedRxiv, 2020 | 190 | 2020 |
Hematopoietic stem cell transplantation in primary immunodeficiency diseases: current status and future perspectives R Castagnoli, OM Delmonte, E Calzoni, LD Notarangelo Frontiers in pediatrics 7, 295, 2019 | 181 | 2019 |
A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2 S Nolan, M Vignali, M Klinger, JN Dines, IM Kaplan, E Svejnoha, T Craft, ... Research square, 2020 | 161 | 2020 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 137 | 2022 |
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice M Recher, SO Burns, MA de la Fuente, S Volpi, C Dahlberg, JE Walter, ... Blood, The Journal of the American Society of Hematology 119 (12), 2819-2828, 2012 | 132 | 2012 |
RAG deficiency: two genes, many diseases OM Delmonte, C Schuetz, LD Notarangelo Journal of clinical immunology 38, 646-655, 2018 | 118 | 2018 |
HGID Lab; NIAID-USUHS Immune Response to COVID Group; COVID Clinicians; COVID-STORM Clinicians; Imagine COVID Group; French COVID Cohort Study Group; Milieu Intérieur … P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 91 | 2020 |
Antibody responses to the SARS-CoV-2 vaccine in individuals with various inborn errors of immunity OM Delmonte, JRE Bergerson, PD Burbelo, JR Durkee-Shock, K Dobbs, ... Journal of Allergy and Clinical Immunology 148 (5), 1192-1197, 2021 | 90 | 2021 |
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, FA Ali, ... Nature medicine 27 (9), 1646-1654, 2021 | 88 | 2021 |
Inborn errors of immunity with immune dysregulation: from bench to bedside OM Delmonte, R Castagnoli, E Calzoni, LD Notarangelo Frontiers in pediatrics 7, 353, 2019 | 87 | 2019 |
Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia M Bosticardo, F Pala, E Calzoni, OM Delmonte, K Dobbs, CL Gardner, ... Blood advances 4 (12), 2611-2616, 2020 | 83 | 2020 |
Neutralizing type‐I interferon autoantibodies are associated with delayed viral clearance and intensive care unit admission in patients with COVID‐19 MS Abers, LB Rosen, OM Delmonte, E Shaw, P Bastard, L Imberti, ... Immunology and cell biology 99 (9), 917-921, 2021 | 81 | 2021 |
Autoantibodies against type I IFNs in patients with life-threatening COVID-19. Science. 370: eabd4585 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... | 81 | 2020 |