Contribution of the endoplasmic reticulum to peroxisome formation D Hoepfner, D Schildknegt, I Braakman, P Philippsen, HF Tabak Cell 122 (1), 85-95, 2005 | 589 | 2005 |
A role for Vps1p, actin, and the Myo2p motor in peroxisome abundance and inheritance in Saccharomyces cerevisiae D Hoepfner, M Van Den Berg, P Philippsen, HF Tabak, EH Hettema The Journal of cell biology 155 (6), 979-990, 2001 | 374 | 2001 |
Selective and specific inhibition of the Plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin D Hoepfner, CW McNamara, CS Lim, C Studer, R Riedl, T Aust, ... Cell host & microbe 11 (6), 654-663, 2012 | 246 | 2012 |
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions D Hoepfner, SB Helliwell, H Sadlish, S Schuierer, I Filipuzzi, S Brachat, ... Microbiological research 169 (2-3), 107-120, 2014 | 167 | 2014 |
Dark chemical matter as a promising starting point for drug lead discovery AM Wassermann, E Lounkine, D Hoepfner, G Le Goff, FJ King, C Studer, ... Nature chemical biology 11 (12), 958-966, 2015 | 141 | 2015 |
Evidence for a functionally relevant rocaglamide binding site on the eIF4A–RNA complex H Sadlish, G Galicia-Vazquez, CG Paris, T Aust, B Bhullar, L Chang, ... ACS chemical biology 8 (7), 1519-1527, 2013 | 138 | 2013 |
A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits O Gadal, D Strauß, J Braspenning, D Hoepfner, E Petfalski, P Philippsen, ... The EMBO Journal 20 (14), 3695-3704, 2001 | 121 | 2001 |
Biosynthesis of fragin is controlled by a novel quorum sensing signal C Jenul, S Sieber, C Daeppen, A Mathew, M Lardi, G Pessi, D Hoepfner, ... Nature communications 9 (1), 1297, 2018 | 117 | 2018 |
Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex P Stelter, R Kunze, D Flemming, D Höpfner, M Diepholz, P Philippsen, ... Nature Cell Biology 9 (7), 788-796, 2007 | 114 | 2007 |
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens G Michlits, M Hubmann, SH Wu, G Vainorius, E Budusan, S Zhuk, ... Nature methods 14 (12), 1191-1197, 2017 | 110 | 2017 |
Nannocystin A: an elongation factor 1 inhibitor from myxobacteria with differential anti‐cancer properties P Krastel, S Roggo, M Schirle, NT Ross, F Perruccio, P Aspesi Jr, T Aust, ... Angewandte Chemie International Edition 54 (35), 10149-10154, 2015 | 105 | 2015 |
Cytoplasmic dynein is required to oppose the force that moves nuclei towards the hyphal tip in the filamentous ascomycete Ashbya gossypii C Alberti-Segui, F Dietrich, R Altmann-Jöhl, D Hoepfner, P Philippsen Journal of cell science 114 (5), 975-986, 2001 | 103 | 2001 |
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks K Shimada, I Filipuzzi, M Stahl, SB Helliwell, C Studer, D Hoepfner, ... Molecular cell 51 (6), 829-839, 2013 | 90 | 2013 |
The natural product cavinafungin selectively interferes with Zika and dengue virus replication by inhibition of the host signal peptidase D Estoppey, CM Lee, M Janoschke, BH Lee, KF Wan, H Dong, P Mathys, ... Cell reports 19 (3), 451-460, 2017 | 87 | 2017 |
Formation of peroxisomes: present and past HF Tabak, D Hoepfner, A Vd Zand, HJ Geuze, I Braakman, MA Huynen Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1763 (12), 1647-1654, 2006 | 77 | 2006 |
Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon T Junne, J Wong, C Studer, T Aust, BW Bauer, M Beibel, B Bhullar, ... Journal of cell science 128 (6), 1217-1229, 2015 | 72 | 2015 |
The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells G Kallifatidis, D Hoepfner, T Jaeg, EA Guzmán, AE Wright Marine drugs 11 (9), 3500-3516, 2013 | 72 | 2013 |
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics U Elling, RA Wimmer, A Leibbrandt, T Burkard, G Michlits, A Leopoldi, ... Nature 550 (7674), 114-118, 2017 | 67 | 2017 |
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease S Khare, SL Roach, SW Barnes, D Hoepfner, JR Walker, AK Chatterjee, ... PLoS Pathogens 11 (7), e1005058, 2015 | 67 | 2015 |
Time-Lapse Video Microscopy Analysis Reveals Astral Microtubule Detachment in the Yeast Spindle Pole Mutantcnm67 D Hoepfner, A Brachat, P Philippsen Molecular biology of the cell 11 (4), 1197-1211, 2000 | 62 | 2000 |