Identification of preexisting adaptive immunity to Cas9 proteins in humans CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ... Nature medicine 25 (2), 249-254, 2019 | 950 | 2019 |
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells DP Dever, RO Bak, A Reinisch, J Camarena, G Washington, CE Nicolas, ... Nature 539 (7629), 384-389, 2016 | 916 | 2016 |
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, ... Nature medicine 24 (8), 1216-1224, 2018 | 740 | 2018 |
CRISPR/Cas9 genome editing in human hematopoietic stem cells RO Bak, DP Dever, MH Porteus Nature protocols 13 (2), 358-376, 2018 | 289 | 2018 |
Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ... Cell stem cell 24 (5), 821-828. e5, 2019 | 167 | 2019 |
Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease SH Park, CM Lee, DP Dever, TH Davis, J Camarena, W Srifa, Y Zhang, ... Nucleic acids research 47 (15), 7955-7972, 2019 | 146 | 2019 |
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6 RO Bak, DP Dever, A Reinisch, D Cruz Hernandez, R Majeti, MH Porteus Elife 6, e27873, 2017 | 123 | 2017 |
Global transcriptional response to CRISPR/Cas9-AAV6-based genome editing in CD34+ hematopoietic stem and progenitor cells MK Cromer, S Vaidyanathan, DE Ryan, B Curry, AB Lucas, J Camarena, ... Molecular Therapy 26 (10), 2431-2442, 2018 | 113 | 2018 |
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, ... Science translational medicine 13 (598), eabf2444, 2021 | 105 | 2021 |
Priming human repopulating hematopoietic stem and progenitor cells for Cas9/sgRNA gene targeting CT Charlesworth, J Camarena, MK Cromer, S Vaidyanathan, RO Bak, ... Molecular Therapy-Nucleic Acids 12, 89-104, 2018 | 92 | 2018 |
Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice AC Wilkinson, DP Dever, R Baik, J Camarena, I Hsu, CT Charlesworth, ... Nature Communications 12 (1), 686, 2021 | 82 | 2021 |
2,3,7,8-Tetracholorodibenzo-p-Dioxin Exposure Disrupts Granule Neuron Precursor Maturation in the Developing Mouse Cerebellum LL Collins, MA Williamson, BD Thompson, DP Dever, TA Gasiewicz, ... Toxicological sciences 103 (1), 125-136, 2008 | 82 | 2008 |
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ... Nature medicine 27 (4), 677-687, 2021 | 66 | 2021 |
The changing landscape of gene editing in hematopoietic stem cells: a step towards Cas9 clinical translation DP Dever, MH Porteus Current opinion in hematology 24 (6), 481-488, 2017 | 61 | 2017 |
The aryl hydrocarbon receptor contributes to the proliferation of human medulloblastoma cells DP Dever, LA Opanashuk Molecular pharmacology 81 (5), 669-678, 2012 | 60 | 2012 |
Subchronic polychlorinated biphenyl (Aroclor 1254) exposure produces oxidative damage and neuronal death of ventral midbrain dopaminergic systems DW Lee, SA Notter, M Thiruchelvam, DP Dever, R Fitzpatrick, ... Toxicological Sciences 125 (2), 496-508, 2012 | 60 | 2012 |
Aryl hydrocarbon receptor deletion in cerebellar granule neuron precursors impairs neurogenesis DP Dever, ZO Adham, B Thompson, M Genestine, J Cherry, ... Developmental neurobiology 76 (5), 533-550, 2016 | 50 | 2016 |
CRISPR/Cas9 genome engineering in engraftable human brain-derived neural stem cells DP Dever, SG Scharenberg, J Camarena, EJ Kildebeck, JT Clark, ... Iscience 15, 524-535, 2019 | 32 | 2019 |
The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells R Sharma, DP Dever, CM Lee, A Azizi, Y Pan, J Camarena, T Köhnke, ... Nature communications 12 (1), 472, 2021 | 23 | 2021 |
Technical considerations for the use of CRISPR/Cas9 in hematology research MC Gundry, DP Dever, D Yudovich, DE Bauer, S Haas, AC Wilkinson, ... Experimental hematology 54, 4-11, 2017 | 15 | 2017 |