Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer B Sahu, M Laakso, K Ovaska, T Mirtti, J Lundin, A Rannikko, A Sankila, ... The EMBO journal 30 (19), 3962-3976, 2011 | 420 | 2011 |
FZD4 as a Mediator of ERG Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells S Gupta, K Iljin, H Sara, JP Mpindi, T Mirtti, P Vainio, J Rantala, K Alanen, ... Cancer research 70 (17), 6735-6745, 2010 | 312 | 2010 |
Stat3 promotes metastatic progression of prostate cancer J Abdulghani, L Gu, A Dagvadorj, J Lutz, B Leiby, G Bonuccelli, ... The American journal of pathology 172 (6), 1717-1728, 2008 | 312 | 2008 |
Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer P Vainio, S Gupta, K Ketola, T Mirtti, JP Mpindi, P Kohonen, V Fey, ... The American journal of pathology 178 (2), 525-536, 2011 | 171 | 2011 |
Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway A Dagvadorj, S Collins, JB Jomain, J Abdulghani, J Karras, T Zellweger, ... Endocrinology 148 (7), 3089-3101, 2007 | 167 | 2007 |
Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo L Gu, P Vogiatzi, M Puhr, A Dagvadorj, J Lutz, A Ryder, S Addya, ... Endocrine-related cancer 17 (2), 481, 2010 | 156 | 2010 |
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion M Björkman, P Östling, V Härmä, J Virtanen, JP Mpindi, J Rantala, T Mirtti, ... Oncogene 31 (29), 3444-3456, 2012 | 130 | 2012 |
Upstaging of urothelial cancer at the time of radical cystectomy: factors associated with upstaging and its effect on outcome P Turker, PJ Bostrom, ML Wroclawski, B van Rhijn, H Kortekangas, C Kuk, ... BJU international 110 (6), 804-811, 2012 | 127 | 2012 |
Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins P Vainio, L Lehtinen, T Mirtti, M Hilvo, T Seppänen-Laakso, J Virtanen, ... Oncotarget 2 (12), 1176, 2011 | 115 | 2011 |
Rac1 nucleocytoplasmic shuttling drives nuclear shape changes and tumor invasion I Navarro-Lerida, T Pellinen, SA Sanchez, MC Guadamillas, Y Wang, ... Developmental cell 32 (3), 318-334, 2015 | 98 | 2015 |
High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer P Vainio, JP Mpindi, P Kohonen, V Fey, T Mirtti, KA Alanen, M Perälä, ... PloS one 7 (6), e39801, 2012 | 95 | 2012 |
Transformation‐specific matrix metalloproteinases (MMP)‐7 and MMP‐13 are expressed by tumour cells in epidermolysis bullosa‐associated squamous cell carcinomas AK Kivisaari, M Kallajoki, T Mirtti, JA McGrath, JW Bauer, F Weber, ... British Journal of Dermatology 158 (4), 778-785, 2008 | 74 | 2008 |
STAT5A/B gene locus undergoes amplification during human prostate cancer progression BR Haddad, L Gu, T Mirtti, A Dagvadorj, P Vogiatzi, DT Hoang, R Bajaj, ... The American journal of pathology 182 (6), 2264-2275, 2013 | 58 | 2013 |
Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models V Härmä, M Knuuttila, J Virtanen, T Mirtti, P Kohonen, P Kovanen, ... Oncogene 31 (16), 2075-2089, 2012 | 51 | 2012 |
Nuclear Stat5a/b predicts early recurrence and prostate cancer–specific death in patients treated by radical prostatectomy T Mirtti, BE Leiby, J Abdulghani, E Aaltonen, M Pavela, A Mamtani, ... Human pathology 44 (3), 310-319, 2013 | 50 | 2013 |
Expression of cystatins, high molecular weight cytokeratin, and proliferation markers in prostatic adenocarcinoma and hyperplasia T Mirtti, K Alanen, M Kallajoki, A Rinne, KO Söderström The Prostate 54 (4), 290-298, 2003 | 46 | 2003 |
Pharmacologic Suppression of JAK1/2 by JAK1/2 Inhibitor AZD1480 Potently Inhibits IL-6–Induced Experimental Prostate Cancer Metastases Formation L Gu, P Talati, P Vogiatzi, AL Romero-Weaver, J Abdulghani, Z Liao, ... Molecular cancer therapeutics 13 (5), 1246-1258, 2014 | 44 | 2014 |
Does patient age affect survival after radical cystectomy? D Horovitz, P Turker, PJ Bostrom, T Mirtti, M Nurmi, C Kuk, G Kulkarni, ... BJU international 110 (11b), E486-E493, 2012 | 43 | 2012 |
Group IIA phospholipase A2 as a prognostic marker in prostate cancer: relevance to clinicopathological variables and disease‐specific mortality T Mirtti, VJO Laine, H Hiekkanen, S Hurme, O Rowe, TJ Nevalainen, ... Apmis 117 (3), 151-161, 2009 | 43 | 2009 |
Sex differences in bladder cancer outcomes among smokers with advanced bladder cancer PJ Boström, S Alkhateeb, G Trottier, PZ Athanasopoulos, T Mirtti, ... BJU international 109 (1), 70-76, 2012 | 37 | 2012 |