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Robert T Abraham
Robert T Abraham
EVP and Head of Cancer Biology, Odyssey Therapeutics
在 odysseytx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13277*2021
Cell cycle checkpoint signaling through the ATM and ATR kinases
RT Abraham
Genes & development 15 (17), 2177-2196, 2001
27532001
The PI3K pathway in human disease
DA Fruman, H Chiu, BD Hopkins, S Bagrodia, LC Cantley, RT Abraham
Cell 170 (4), 605-635, 2017
21692017
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ...
Genes & development 13 (11), 1422-1437, 1999
16461999
Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin
CC Hudson, M Liu, GG Chiang, DM Otterness, DC Loomis, F Kaper, ...
Molecular and cellular biology 22 (20), 7004-7014, 2002
15332002
A role for ATR in the DNA damage-induced phosphorylation of p53
RS Tibbetts, KM Brumbaugh, JM Williams, JN Sarkaria, WA Cliby, ...
Genes & development 13 (2), 152-157, 1999
14511999
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
JN Sarkaria, EC Busby, RS Tibbetts, P Roos, Y Taya, LM Karnitz, ...
Cancer research 59 (17), 4375-4382, 1999
13471999
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
GJ Brunn, CC Hudson, A Sekulic, JM Williams, H Hosoi, PJ Houghton, ...
Science 277 (5322), 99-101, 1997
12291997
Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells (∗)
CJ Sabers, MM Martin, GJ Brunn, JM Williams, FJ Dumont, G Wiederrecht, ...
Journal of Biological Chemistry 270 (2), 815-822, 1995
11371995
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells
A Sekulic, CC Hudson, JL Homme, P Yin, DM Otterness, LM Karnitz, ...
Cancer research 60 (13), 3504-3513, 2000
9742000
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase
G Powis, R Bonjouklian, MM Berggren, A Gallegos, R Abraham, ...
Cancer research 54 (9), 2419-2423, 1994
9361994
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002.
GJ Brunn, J Williams, C Sabers, G Wiederrecht, JC Lawrence Jr, ...
The EMBO journal 15 (19), 5256-5267, 1996
8931996
Immunopharmacology of rapamycin
RT Abraham, GJ Wiederrecht
Annual review of immunology 14 (1), 483-510, 1996
8911996
Jurkat T cells and development of the T-cell receptor signalling paradigm
RT Abraham, A Weiss
Nature reviews immunology 4 (4), 301-308, 2004
7712004
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
RS Tibbetts, D Cortez, KM Brumbaugh, R Scully, D Livingston, SJ Elledge, ...
Genes & development 14 (23), 2989-3002, 2000
6982000
Phosphorylation of Mammalian Target of Rapamycin (mTOR) at Ser-2448 IsMediated by p70S6 Kinase
GG Chiang, RT Abraham
Journal of Biological Chemistry 280 (27), 25485-25490, 2005
6672005
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
JN Sarkaria, RS Tibbetts, EC Busby, AP Kennedy, DE Hill, RT Abraham
Cancer research 58 (19), 4375-4382, 1998
6611998
PI 3-kinase related kinases:‘big’players in stress-induced signaling pathways
RT Abraham
DNA repair 3 (8-9), 883-887, 2004
6342004
Distinct requirements for Ras oncogenesis in human versus mouse cells
NM Hamad, JH Elconin, AE Karnoub, W Bai, JN Rich, RT Abraham, ...
Genes & development 16 (16), 2045-2057, 2002
5412002
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference
C Zhu, J Zhao, M Bibikova, JD Leverson, E Bossy-Wetzel, JB Fan, ...
Molecular biology of the cell 16 (7), 3187-3199, 2005
5152005
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