Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13277* | 2021 |
Cell cycle checkpoint signaling through the ATM and ATR kinases RT Abraham Genes & development 15 (17), 2177-2196, 2001 | 2753 | 2001 |
The PI3K pathway in human disease DA Fruman, H Chiu, BD Hopkins, S Bagrodia, LC Cantley, RT Abraham Cell 170 (4), 605-635, 2017 | 2169 | 2017 |
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ... Genes & development 13 (11), 1422-1437, 1999 | 1646 | 1999 |
Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin CC Hudson, M Liu, GG Chiang, DM Otterness, DC Loomis, F Kaper, ... Molecular and cellular biology 22 (20), 7004-7014, 2002 | 1533 | 2002 |
A role for ATR in the DNA damage-induced phosphorylation of p53 RS Tibbetts, KM Brumbaugh, JM Williams, JN Sarkaria, WA Cliby, ... Genes & development 13 (2), 152-157, 1999 | 1451 | 1999 |
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine JN Sarkaria, EC Busby, RS Tibbetts, P Roos, Y Taya, LM Karnitz, ... Cancer research 59 (17), 4375-4382, 1999 | 1347 | 1999 |
Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin GJ Brunn, CC Hudson, A Sekulic, JM Williams, H Hosoi, PJ Houghton, ... Science 277 (5322), 99-101, 1997 | 1229 | 1997 |
Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells (∗) CJ Sabers, MM Martin, GJ Brunn, JM Williams, FJ Dumont, G Wiederrecht, ... Journal of Biological Chemistry 270 (2), 815-822, 1995 | 1137 | 1995 |
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells A Sekulic, CC Hudson, JL Homme, P Yin, DM Otterness, LM Karnitz, ... Cancer research 60 (13), 3504-3513, 2000 | 974 | 2000 |
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase G Powis, R Bonjouklian, MM Berggren, A Gallegos, R Abraham, ... Cancer research 54 (9), 2419-2423, 1994 | 936 | 1994 |
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002. GJ Brunn, J Williams, C Sabers, G Wiederrecht, JC Lawrence Jr, ... The EMBO journal 15 (19), 5256-5267, 1996 | 893 | 1996 |
Immunopharmacology of rapamycin RT Abraham, GJ Wiederrecht Annual review of immunology 14 (1), 483-510, 1996 | 891 | 1996 |
Jurkat T cells and development of the T-cell receptor signalling paradigm RT Abraham, A Weiss Nature reviews immunology 4 (4), 301-308, 2004 | 771 | 2004 |
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress RS Tibbetts, D Cortez, KM Brumbaugh, R Scully, D Livingston, SJ Elledge, ... Genes & development 14 (23), 2989-3002, 2000 | 698 | 2000 |
Phosphorylation of Mammalian Target of Rapamycin (mTOR) at Ser-2448 IsMediated by p70S6 Kinase GG Chiang, RT Abraham Journal of Biological Chemistry 280 (27), 25485-25490, 2005 | 667 | 2005 |
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin JN Sarkaria, RS Tibbetts, EC Busby, AP Kennedy, DE Hill, RT Abraham Cancer research 58 (19), 4375-4382, 1998 | 661 | 1998 |
PI 3-kinase related kinases:‘big’players in stress-induced signaling pathways RT Abraham DNA repair 3 (8-9), 883-887, 2004 | 634 | 2004 |
Distinct requirements for Ras oncogenesis in human versus mouse cells NM Hamad, JH Elconin, AE Karnoub, W Bai, JN Rich, RT Abraham, ... Genes & development 16 (16), 2045-2057, 2002 | 541 | 2002 |
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference C Zhu, J Zhao, M Bibikova, JD Leverson, E Bossy-Wetzel, JB Fan, ... Molecular biology of the cell 16 (7), 3187-3199, 2005 | 515 | 2005 |