IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo A Venkatanarayan, P Raulji, W Norton, D Chakravarti, C Coarfa, X Su, ... Nature 517 (7536), 626-630, 2015 | 132 | 2015 |
Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma MM Singh, B Johnson, A Venkatarayan, ER Flores, J Zhang, X Su, ... Neuro-oncology 17 (11), 1463-1473, 2015 | 85 | 2015 |
ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma I Yen, F Shanahan, J Lee, YS Hong, SJ Shin, AR Moore, J Sudhamsu, ... Nature 594 (7863), 418-423, 2021 | 84 | 2021 |
Pharmacological induction of RAS-GTP confers RAF inhibitor sensitivity in KRAS mutant tumors I Yen, F Shanahan, M Merchant, C Orr, T Hunsaker, M Durk, H La, ... Cancer Cell 34 (4), 611-625. e7, 2018 | 81 | 2018 |
Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8 D Chakravarti, X Su, MS Cho, NHB Bui, C Coarfa, A Venkatanarayan, ... Proceedings of the National Academy of Sciences 111 (5), E572-E581, 2014 | 80 | 2014 |
Copy number gain of hsa-miR-569 at 3q26. 2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers P Chaluvally-Raghavan, F Zhang, S Pradeep, MP Hamilton, X Zhao, ... Cancer Cell 26 (6), 863-879, 2014 | 53 | 2014 |
Noxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress CO Eno, G Zhao, A Venkatanarayan, B Wang, ER Flores, C Li Free radical Biology and Medicine 65, 26-37, 2013 | 53 | 2013 |
TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway X Su, M Napoli, HA Abbas, A Venkatanarayan, NHB Bui, C Coarfa, YJ Gi, ... Oncogene 36 (17), 2377-2393, 2017 | 42 | 2017 |
ΔNp63/DGCR8-dependent microRNAs mediate therapeutic efficacy of HDAC inhibitors in cancer M Napoli, A Venkatanarayan, P Raulji, BA Meyers, W Norton, LS Mangala, ... Cancer cell 29 (6), 874-888, 2016 | 41 | 2016 |
Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73 A Venkatanarayan, P Raulji, W Norton, ER Flores Cell Cycle 15 (2), 164-171, 2016 | 38 | 2016 |
Dimerization induced by C-terminal 14–3–3 binding is sufficient for BRAF kinase activation NPD Liau, A Venkatanarayan, JG Quinn, W Phung, S Malek, ... Biochemistry 59 (41), 3982-3992, 2020 | 34 | 2020 |
CRAF dimerization with ARAF regulates KRAS-driven tumor growth A Venkatanarayan, J Liang, I Yen, F Shanahan, B Haley, L Phu, ... Cell reports 38 (6), 2022 | 27 | 2022 |
Activating p53 family member TAp63: a novel therapeutic strategy for targeting p53‐altered tumors PH Gunaratne, Y Pan, AK Rao, C Lin, A Hernandez‐Herrera, K Liang, ... Cancer 125 (14), 2409-2422, 2019 | 22 | 2019 |
ARID1A mutations confer intrinsic and acquired resistance to cetuximab treatment in colorectal cancer RM Johnson, X Qu, CF Lin, LY Huw, A Venkatanarayan, E Sokol, FS Ou, ... Nature communications 13 (1), 5478, 2022 | 16 | 2022 |
NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma GV Hegde, C de la Cruz, JM Giltnane, L Crocker, A Venkatanarayan, ... Elife 8, e46551, 2019 | 11 | 2019 |
Zfh-2 facilitates Notch-induced apoptosis in the CNS and appendages of Drosophila melanogaster AR Guntur, A Venkatanarayan, S Gangula, MJ Lundell Developmental Biology 475, 65-79, 2021 | 10 | 2021 |
Hunchback prevents notch-induced apoptosis in the serotonergic lineage of Drosophila Melanogaster E Pérez, A Venkatanarayan, MJ Lundell Developmental biology 486, 109-120, 2022 | 4 | 2022 |
Partners in Crime: Clandestine Operations among RAS-RAF Accomplices in Promoting Tumorigenesis A Venkatanarayan, S Malek Molecular cell 76 (6), 853-855, 2019 | 1 | 2019 |
CRAF-mediated inactivation of epigenetic repressor complexes promotes KRAS-driven tumorigenesis. A Venkatanarayan, C Klijn, S Malek MOLECULAR CANCER RESEARCH 18 (5), 60-60, 2020 | | 2020 |
Abstract B14: CRAF-mediated inactivation of epigenetic repressor complexes promotes KRAS-driven tumorigenesis A Venkatanarayan, C Klijn, S Malek Molecular Cancer Research 18 (5_Supplement), B14-B14, 2020 | | 2020 |