A Genomic Survey of Positive Selection in Burkholderia pseudomallei Provides Insights into the Evolution of Accidental Virulence T Nandi, C Ong, AP Singh, J Boddey, T Atkins, M Sarkar-Tyson, ... PLoS pathogens 6 (4), e1000845, 2010 | 153 | 2010 |
A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A A Cruz-Migoni, GM Hautbergue, PJ Artymiuk, PJ Baker, M Bokori-Brown, ... Science 334 (6057), 821-824, 2011 | 128 | 2011 |
Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development MG Moule, CM Hemsley, Q Seet, JA Guerra-Assunção, J Lim, ... MBio 5 (1), 10.1128/mbio. 00926-13, 2014 | 94 | 2014 |
Burkholderia pseudomallei: animal models of infection RW Titball, P Russell, J Cuccui, A Easton, A Haque, T Atkins, ... Transactions of the Royal Society of Tropical Medicine and Hygiene 102, S111 …, 2008 | 89 | 2008 |
Diversity oriented biosynthesis via accelerated evolution of modular gene clusters A Wlodek, SG Kendrew, NJ Coates, A Hold, J Pogwizd, S Rudder, ... Nature communications 8 (1), 1206, 2017 | 86 | 2017 |
Identification of a LolC Homologue in Burkholderia pseudomallei, a Novel Protective Antigen for Melioidosis DN Harland, K Chu, A Haque, M Nelson, NJ Walker, M Sarkar-Tyson, ... Infection and immunity 75 (8), 4173-4180, 2007 | 82 | 2007 |
Polysaccharides and virulence of Burkholderia pseudomallei M Sarkar-Tyson, JE Thwaite, SV Harding, SJ Smither, PCF Oyston, ... Journal of medical microbiology 56 (8), 1005-1010, 2007 | 78 | 2007 |
Progress toward development of vaccines against melioidosis: A review M Sarkar-Tyson, RW Titball Clinical therapeutics 32 (8), 1437-1445, 2010 | 74 | 2010 |
Protective efficacy of heat-inactivated B. thailandensis, B. mallei or B. pseudomallei against experimental melioidosis and glanders M Sarkar-Tyson, SJ Smither, SV Harding, TP Atkins, RW Titball Vaccine 27 (33), 4447-4451, 2009 | 73 | 2009 |
Superoxide dismutase C is required for intracellular survival and virulence of Burkholderia pseudomallei M Vanaporn, M Wand, SL Michell, M Sarkar-Tyson, P Ireland, S Goldman, ... Microbiology 157 (8), 2392-2400, 2011 | 72 | 2011 |
Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region J Cuccui, TS Milne, N Harmer, AJ George, SV Harding, RE Dean, ... Infection and immunity 80 (3), 1209-1221, 2012 | 71 | 2012 |
Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles T Nandi, MTG Holden, X Didelot, K Mehershahi, JA Boddey, I Beacham, ... Genome research 25 (1), 129-141, 2015 | 67 | 2015 |
The identification of surface proteins of Burkholderia pseudomallei SV Harding, M Sarkar-Tyson, SJ Smither, TP Atkins, PCF Oyston, ... Vaccine 25 (14), 2664-2672, 2007 | 67 | 2007 |
A novel ERK‐like, CRK‐like protein kinase that modulates growth in Trypanosoma brucei via an autoregulatory C‐terminal extension J Ellis, M Sarkar, E Hendriks, K Matthews Molecular microbiology 53 (5), 1487-1499, 2004 | 60 | 2004 |
A Burkholderia pseudomallei macrophage infectivity potentiator-like protein has rapamycin-inhibitable peptidylprolyl isomerase activity and pleiotropic effects on virulence IH Norville, NJ Harmer, SV Harding, G Fischer, KE Keith, KA Brown, ... Infection and immunity 79 (11), 4299-4307, 2011 | 56 | 2011 |
Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo PM Ireland, RM McMahon, LE Marshall, M Halili, E Furlong, S Tay, ... Antioxidants & redox signaling 20 (4), 606-617, 2014 | 55 | 2014 |
Global Map of Growth-Regulated Gene Expression in Burkholderia pseudomallei, the Causative Agent of Melioidosis F Rodrigues, M Sarkar-Tyson, SV Harding, SH Sim, HH Chua, CH Lin, ... Journal of bacteriology 188 (23), 8178-8188, 2006 | 55 | 2006 |
Integrated human-virus metabolic stoichiometric modelling predicts host-based antiviral targets against Chikungunya, Dengue and Zika viruses S Aller, A Scott, M Sarkar-Tyson, OS Soyer Journal of The Royal Society Interface 15 (146), 20180125, 2018 | 46 | 2018 |
A novel selection regime for differentiation defects demonstrates an essential role for the stumpy form in the life cycle of the African trypanosome M Tasker, J Wilson, M Sarkar, E Hendriks, K Matthews Molecular Biology of the Cell 11 (5), 1905-1917, 2000 | 45 | 2000 |
Trehalase plays a role in macrophage colonization and virulence of Burkholderia pseudomallei in insect and mammalian hosts M Vanaporn, M Sarkar-Tyson, A Kovacs-Simon, PM Ireland, P Pumirat, ... Virulence 8 (1), 30-40, 2017 | 35 | 2017 |