Mechanistic basis for high stereoselectivity and broad substrate scope in the (salen) Co (III)-catalyzed hydrolytic kinetic resolution DD Ford, LPC Nielsen, SJ Zuend, CB Musgrave, EN Jacobsen Journal of the American Chemical Society 135 (41), 15595-15608, 2013 | 138 | 2013 |
On-and off-cycle catalyst cooperativity in anion-binding catalysis DD Ford, D Lehnherr, CR Kennedy, EN Jacobsen Journal of the American Chemical Society 138 (25), 7860-7863, 2016 | 89 | 2016 |
Mechanism-guided development of a highly active bis-thiourea catalyst for anion-abstraction catalysis CR Kennedy, D Lehnherr, NS Rajapaksa, DD Ford, Y Park, EN Jacobsen Journal of the American Chemical Society 138 (41), 13525-13528, 2016 | 79 | 2016 |
Mechanistic Basis for High Reactivity of (salen) Co–OTs in the Hydrolytic Kinetic Resolution of Terminal Epoxides LPC Nielsen, SJ Zuend, DD Ford, EN Jacobsen The Journal of Organic Chemistry 77 (5), 2486-2495, 2012 | 66 | 2012 |
Anion-abstraction catalysis: the cooperative mechanism of α-chloroether activation by dual hydrogen-bond donors DD Ford, D Lehnherr, CR Kennedy, EN Jacobsen ACS catalysis 6 (7), 4616-4620, 2016 | 61 | 2016 |
Development of a lean process to the lead-free primary explosive DBX-1 DD Ford, S Lenahan, M Jörgensen, P Dubé, M Delude, PE Concannon, ... Organic Process Research & Development 19 (6), 673-680, 2015 | 42 | 2015 |
Conformational control of chiral amido-thiourea catalysts enables improved activity and enantioselectivity D Lehnherr, DD Ford, AJ Bendelsmith, CR Kennedy, EN Jacobsen Organic letters 18 (13), 3214-3217, 2016 | 40 | 2016 |
Silanediol anion binding and enantioselective catalysis JW Attard, K Osawa, Y Guan, J Hatt, S Kondo, A Mattson Synthesis 51 (10), 2107-2115, 2019 | 21 | 2019 |
A scalable route for the regio-and enantioselective preparation of a tetrazole prodrug: application to the multi-gram-scale synthesis of a PCSK9 inhibitor A Akin, MT Barrila, TA Brandt, AMR Dechert-Schmitt, P Dube, DD Ford, ... Organic Process Research & Development 21 (12), 1990-2000, 2017 | 20 | 2017 |
Hydronium Copper (II)‐tris (5‐nitrotetrazolate) Trihydrate–A Primary Explosive M Krawiec, SR Anderson, P Dubé, DD Ford, JS Salan, S Lenahan, ... Propellants, Explosives, Pyrotechnics 40 (4), 457-459, 2015 | 19 | 2015 |
Scalable on-demand production of purified diazomethane suitable for sensitive catalytic reactions JW Sheeran, K Campbell, CP Breen, G Hummel, C Huang, A Datta, ... Organic Process Research & Development 25 (3), 522-528, 2020 | 17 | 2020 |
Remarkable Influence of Cobalt Catalysis on Epoxide Ring-Opening with Sulfoxonium Ylides ML Jamieson, NZ Brant, MA Brimble, DP Furkert Synthesis 49 (17), 3952-3956, 2017 | 15 | 2017 |
Axial chirality in the sotorasib drug substance, Part 2: Leveraging a high-temperature thermal racemization to recycle the classical resolution waste stream MG Beaver, DB Brown, K Campbell, YQ Fang, DD Ford, N Mardirossian, ... Organic Process Research & Development 26 (9), 2636-2645, 2022 | 14 | 2022 |
Implementing continuous manufacturing for the final methylation step in the AMG 397 process to deliver key quality attributes JK Tom, MM Achmatowicz, MG Beaver, J Colyer, A Ericson, TL Hwang, ... Organic Process Research & Development 25 (3), 486-499, 2021 | 13 | 2021 |
Boron-containing compounds F Amann, J BÜRGLER, Y Fang, D Ford, D McGarry US Patent 10,889,600, 2021 | 7 | 2021 |
Process for racemizing and isolating atropisomers of 7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl) pyrido [2, 3-d] pyrimidine-2, 4 (1h, 3h)-dione MG Beaver, MT Corbett, Y Fang, DD Ford, AT Parsons, STP Gabrielle, ... US Patent App. 18/030,685, 2023 | 3 | 2023 |
Boron-containing compounds F Amann, J BÜRGLER, Y Fang, D Ford, D McGarry US Patent 11,560,392, 2023 | 3 | 2023 |
The Role of Catalyst-Catalyst Interactions in Asymmetric Catalysis with (salen) Cobalt (III) Complexes and Hydrogen-Bond Donors DD Ford Harvard University, 2013 | 2 | 2013 |
Automated online chromatographic sample dilution and preparation system AG Amador, Y Fang, DD Ford, MV Goncharuk, G Russell US Patent 11,994,502, 2024 | | 2024 |
A Modular Continuous Manufacturing Platform for Fine Chemicals Via Lithium-Halogen Exchange and Electrophilic Substitution K Campbell, K Nagy, DD Ford, YQ Fang, M Caporello, E Hurlow, A Un, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |