Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers S Onengut-Gumuscu, WM Chen, O Burren, NJ Cooper, AR Quinlan, ... Nature genetics 47 (4), 381-386, 2015 | 697 | 2015 |
Widespread seasonal gene expression reveals annual differences in human immunity and physiology XC Dopico, M Evangelou, RC Ferreira, H Guo, ML Pekalski, DJ Smyth, ... Nature communications 6 (1), 7000, 2015 | 509 | 2015 |
A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes RC Ferreira, H Guo, RMR Coulson, DJ Smyth, ML Pekalski, OS Burren, ... Diabetes 63 (7), 2538-2550, 2014 | 315 | 2014 |
Seven newly identified loci for autoimmune thyroid disease JD Cooper, MJ Simmonds, NM Walker, O Burren, OJ Brand, H Guo, ... Human molecular genetics 21 (23), 5202-5208, 2012 | 188 | 2012 |
Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls MD Fortune, H Guo, O Burren, E Schofield, NM Walker, M Ban, SJ Sawcer, ... Nature genetics 47 (7), 839-846, 2015 | 164 | 2015 |
Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases H Guo, MD Fortune, OS Burren, E Schofield, JA Todd, C Wallace Human molecular genetics 24 (12), 3305-3313, 2015 | 150 | 2015 |
A method for gene‐based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations M Evangelou, DJ Smyth, MD Fortune, OS Burren, NM Walker, H Guo, ... Genetic epidemiology 38 (8), 661-670, 2014 | 73 | 2014 |
Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes WS Thompson, ML Pekalski, HZ Simons, DJ Smyth, X Castro-Dopico, ... Clinical & Experimental Immunology 177 (3), 571-585, 2014 | 69 | 2014 |
Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors ML Pekalski, RC Ferreira, RMR Coulson, AJ Cutler, H Guo, DJ Smyth, ... The Journal of Immunology 190 (6), 2554-2566, 2013 | 69 | 2013 |
Sensitivity to pain expectations: A Bayesian model of individual differences R Hoskin, C Berzuini, D Acosta-Kane, W El-Deredy, H Guo, D Talmi Cognition 182, 127-139, 2019 | 68 | 2019 |
Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping C Wallace, AJ Cutler, N Pontikos, ML Pekalski, OS Burren, JD Cooper, ... PLoS genetics 11 (6), e1005272, 2015 | 64 | 2015 |
Molecular insights into genome-wide association studies of chronic kidney disease-defining traits X Xu, JM Eales, A Akbarov, H Guo, L Becker, D Talavera, F Ashraf, ... Nature communications 9 (1), 4800, 2018 | 62 | 2018 |
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney JM Eales, X Jiang, X Xu, S Saluja, A Akbarov, E Cano-Gamez, ... Nature genetics 53 (5), 630-637, 2021 | 51 | 2021 |
A Bayesian approach to Mendelian randomization with multiple pleiotropic variants C Berzuini, H Guo, S Burgess, L Bernardinelli Biostatistics 21 (1), 86-101, 2020 | 45 | 2020 |
Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics J Rowland, A Akbarov, J Eales, X Xu, JP Dormer, H Guo, M Denniff, ... Kidney international 95 (3), 624-635, 2019 | 45 | 2019 |
Obesity and cancer treatment outcomes: interpreting the complex evidence CGV Slawinski, J Barriuso, H Guo, AG Renehan Clinical Oncology 32 (9), 591-608, 2020 | 44 | 2020 |
Type 1 Diabetes Genetics C, Todd JA, Wallace C, Concannon P, Rich SS. Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants … S Onengut-Gumuscu, WM Chen, O Burren, NJ Cooper, AR Quinlan, ... Nat Genet 47, 381-386, 2015 | 25 | 2015 |
Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes NJ Cooper, CJ Shtir, DJ Smyth, H Guo, AD Swafford, M Zanda, ME Hurles, ... Human molecular genetics 24 (6), 1774-1790, 2015 | 22 | 2015 |
Sufficient covariates and linear propensity analysis H Guo, P Dawid Proceedings of the Thirteenth International Conference on Artificial …, 2010 | 22 | 2010 |
VSEAMS: a pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes OS Burren, H Guo, C Wallace Bioinformatics 30 (23), 3342-3348, 2014 | 20 | 2014 |