The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. SM De Morais, GR Wilkinson, J Blaisdell, K Nakamura, UA Meyer, ... Journal of Biological Chemistry 269 (22), 15419-15422, 1994 | 1324 | 1994 |
Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese. SM De Morais, GR Wilkinson, J Blaisdell, UA Meyer, K Nakamura, ... Molecular pharmacology 46 (4), 594-598, 1994 | 1032 | 1994 |
Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data CR Lee, JA Goldstein, JA Pieper Pharmacogenetics and genomics 12 (3), 251-263, 2002 | 910 | 2002 |
Clinical relevance of genetic polymorphisms in the human CYP2C subfamily JA Goldstein British journal of clinical pharmacology 52 (4), 349-355, 2001 | 882 | 2001 |
The role of the CFP2C9-Leu 359 allelic variant in the tolbutamide polymorphism TH Sullivan-Klose, BI Ghanayem, DA Bell, ZY Zhang, LS Kaminsky, ... Pharmacogenetics and Genomics 6 (4), 341-349, 1996 | 820 | 1996 |
Biochemistry and molecular biology of the human CYP2C subfamily JA Goldstein, SMF de Morais Pharmacogenetics and Genomics 4 (6), 285-300, 1994 | 720 | 1994 |
Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid D Dai, DC Zeldin, JA Blaisdell, B Chanas, SJ Coulter, BI Ghanayem, ... Pharmacogenetics and Genomics 11 (7), 597-607, 2001 | 613 | 2001 |
Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos D Dai, J Tang, R Rose, E Hodgson, RJ Bienstock, HW Mohrenweiser, ... Journal of Pharmacology and Experimental Therapeutics 299 (3), 825-831, 2001 | 492 | 2001 |
Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans JA Goldstein, MB Faletto, M Romkes-Sparks, T Sullivan, S Kitareewan, ... Biochemistry 33 (7), 1743-1752, 1994 | 461 | 1994 |
Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations JA Goldstein, T Ishizaki, K Chiba, SMF de Morais, D Bell, PM Krahn, ... Pharmacogenetics and Genomics 7 (1), 59-64, 1997 | 429 | 1997 |
Halogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins and related products RD Kimbrough, AA Jensen Elsevier, 2012 | 425 | 2012 |
Kidney function influences warfarin responsiveness and hemorrhagic complications NA Limdi, TM Beasley, MF Baird, JA Goldstein, G McGwin, DK Arnett, ... Journal of the American Society of Nephrology 20 (4), 912-921, 2009 | 388 | 2009 |
Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily M Romkes, MB Faletto, JA Blaisdell, JL Raucy, JA Goldstein Biochemistry 30 (13), 3247-3255, 1991 | 357 | 1991 |
Identification of a null allele of CYP2C9 in an African–American exhibiting toxicity to phenytoin RS Kidd, TB Curry, S Gallagher, T Edeki, J Blaisdell, JA Goldstein Pharmacogenetics and Genomics 11 (9), 803-808, 2001 | 348 | 2001 |
Influence of CYP2C9 and VKORC1 1173C/T Genotype on the Risk of Hemorrhagic Complications in African‐American and European‐American Patients on … NA Limdi, G McGwin, JA Goldstein, TM Beasley, DK Arnett, BK Adler, ... Clinical Pharmacology & Therapeutics 83 (2), 312-321, 2008 | 304 | 2008 |
Separation of pure polychlorinated biphenyl isomers into two types of inducers on the basis of induction of cytochrome P-450 or P-448 JA Goldstein, P Hickman, H Bergman, JD Mckinney, MP Walker Chemico-Biological Interactions 17 (1), 69-87, 1977 | 304 | 1977 |
Metabolism of chlorpyrifos by human cytochrome P450 isoforms and human, mouse, and rat liver microsomes J Tang, Y Cao, RL Rose, AA Brimfield, D Dai, JA Goldstein, E Hodgson Drug metabolism and disposition 29 (9), 1201-1204, 2001 | 295 | 2001 |
A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin RJ Ferguson, SMF De Morais, S Benhamou, C Bouchardy, J Blaisdell, ... Journal of Pharmacology and Experimental Therapeutics 284 (1), 356-361, 1998 | 286 | 1998 |
Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor Y Chen, SS Ferguson, M Negishi, JA Goldstein Journal of Pharmacology and Experimental Therapeutics 308 (2), 495-501, 2004 | 285 | 2004 |
Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs TS Klose, JA Blaisdell, JA Goldstein Journal of biochemical and molecular toxicology 13 (6), 289-295, 1999 | 270 | 1999 |