Transport of gabapentin by LAT1 (SLC7A5) D Dickens, SD Webb, S Antonyuk, A Giannoudis, A Owen, S Rädisch, ... Biochemical pharmacology 85 (11), 1672-1683, 2013 | 143 | 2013 |
Lamotrigine is a substrate for OCT1 in brain endothelial cells D Dickens, A Owen, A Alfirevic, A Giannoudis, A Davies, B Weksler, ... Biochemical pharmacology 83 (6), 805-814, 2012 | 98 | 2012 |
Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol D Dickens, GN Chiduza, GSA Wright, M Pirmohamed, SV Antonyuk, ... Scientific reports 7 (1), 43580, 2017 | 74 | 2017 |
MAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins D Lam, D Dickens, EB Reid, SHY Loh, N Moisoi, LM Martins Proceedings of the National Academy of Sciences 106 (29), 11978-11983, 2009 | 50 | 2009 |
A multi-system approach assessing the interaction of anticonvulsants with P-gp D Dickens, SR Yusof, NJ Abbott, B Weksler, IA Romero, PO Couraud, ... PLoS One 8 (5), e64854, 2013 | 36 | 2013 |
Cellular uptake of the atypical antipsychotic clozapine is a carrier-mediated process D Dickens, S Radisch, GN Chiduza, A Giannoudis, MJ Cross, H Malik, ... Molecular pharmaceutics 15 (8), 3557-3572, 2018 | 35 | 2018 |
ABCB1 single nucleotide polymorphisms (1236C> T, 2677G> T, and 3435C> T) do not affect transport activity of human P-glycoprotein D Dickens, A Owen, A Alfirevic, M Pirmohamed Pharmacogenetics and genomics 23 (6), 314-323, 2013 | 35 | 2013 |
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants S Gutbier, S Kyriakou, S Schildknecht, AK Ückert, M Brüll, F Lewis, ... Archives of Toxicology 94, 3105-3123, 2020 | 28 | 2020 |
The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein M Vogler, D Dickens, MJS Dyer, A Owen, M Pirmohamed, GM Cohen Biochemical and biophysical research communications 408 (2), 344-349, 2011 | 27 | 2011 |
Development of fluorine-18 labeled metabolically activated tracers for imaging of drug efflux transporters with positron emission tomography K Sander, E Galante, T Gendron, E Yiannaki, N Patel, TL Kalber, A Badar, ... Journal of Medicinal Chemistry 58 (15), 6058-6080, 2015 | 22 | 2015 |
Misoprostol-Induced Fever and Genetic Polymorphisms in Drug Transporters SLCO1B1 and ABCC4 in Women of Latin American and European Ancestry A Alfirevic, J Durocher, A Elati, W León, D Dickens, S Rädisch, H Box, ... Pharmacogenomics 16 (9), 919-928, 2015 | 20 | 2015 |
The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells K Ide, S Takahashi, K Sakai, Y Taga, T Ueno, D Dickens, R Jenkins, ... Journal of Biological Chemistry 297 (1), 2021 | 19 | 2021 |
A comprehensive functional and clinical analysis of ABCC2 and its impact on treatment response to carbamazepine S Rädisch, D Dickens, T Lang, L Bonnett, R Arlanov, MR Johnson, ... The Pharmacogenomics Journal 14 (5), 481-487, 2014 | 13 | 2014 |
Probenecid increases the concentration of 7-chlorokynurenic acid derived from the prodrug 4-chlorokynurenine within the prefrontal cortex W Patel, L Rimmer, M Smith, L Moss, MA Smith, HR Snodgrass, ... Molecular pharmaceutics 18 (1), 113-123, 2021 | 11 | 2021 |
LAT1, a novel pharmacological target for the treatment of glioblastoma N Cappoli, MD Jenkinson, CD Russo, D Dickens Biochemical Pharmacology 201, 115103, 2022 | 10 | 2022 |
Drug Transporters at the Blood–Brain Barrier D Dickens, S Radisch, M Pirmohamed RSC Drug Discovery Series, 2016 | 6 | 2016 |
Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol. Sci Rep 7: 43580 D Dickens, GN Chiduza, GS Wright, M Pirmohamed, SV Antonyuk, ... | 5 | 2017 |
Drug Transporters: Volume 1: Role and Importance in ADME and Drug Development D Dickens, S Radisch, M Pirmohamed The Royal Society of Chemistry, 2016 | 5 | 2016 |
AV-101, a pro-drug antagonist at the NMDA receptor glycine site, reduces L-Dopa induced dyskinesias in MPTP monkeys M Bourque, L Grégoire, W Patel, D Dickens, R Snodgrass, T Di Paolo Cells 11 (22), 3530, 2022 | 4 | 2022 |
Role of Transporters and Enzymes in Metabolism and Distribution of 4-Chlorokynurenine (AV-101) W Patel, RG Shankar, MA Smith, HR Snodgrass, M Pirmohamed, ... Molecular Pharmaceutics 21 (2), 550-563, 2024 | 1 | 2024 |