Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four … M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10277), 881-891, 2021 | 1380 | 2021 |
Evolution of pathogenicity and sexual reproduction in eight Candida genomes G Butler, MD Rasmussen, MF Lin, MAS Santos, S Sakthikumar, CA Munro, ... Nature 459 (7247), 657-662, 2009 | 1213 | 2009 |
Phylogenetic diversity of stress signalling pathways in fungi E Nikolaou, I Agrafioti, M Stumpf, J Quinn, I Stansfield, AJP Brown BMC Evolutionary Biology 9, 1-18, 2009 | 243 | 2009 |
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus SP Jochems, F Marcon, BF Carniel, M Holloway, E Mitsi, E Smith, ... Nature immunology 19 (12), 1299-1308, 2018 | 163 | 2018 |
Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine WAA de Steenhuijsen Piters, SP Jochems, E Mitsi, J Rylance, S Pojar, ... Nature communications 10 (1), 2981, 2019 | 76 | 2019 |
Polysaccharide-specific memory B cells predict protection against experimental human pneumococcal carriage SH Pennington, S Pojar, E Mitsi, JF Gritzfeld, E Nikolaou, C Solorzano, ... American journal of respiratory and critical care medicine 194 (12), 1523-1531, 2016 | 69 | 2016 |
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, ... Nature communications 10 (1), 3060, 2019 | 59 | 2019 |
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization SP Jochems, K de Ruiter, C Solórzano, A Voskamp, E Mitsi, E Nikolaou, ... The Journal of clinical investigation 129 (10), 2022 | 54 | 2022 |
Nasal pneumococcal density is associated with microaspiration and heightened human alveolar macrophage responsiveness to bacterial pathogens E Mitsi, B Carniel, J Reiné, J Rylance, S Zaidi, A Soares-Schanoski, ... American Journal of Respiratory and Critical Care Medicine 201 (3), 335-347, 2020 | 44 | 2020 |
Pneumococcal within-host diversity during colonization, transmission and treatment G Tonkin-Hill, C Ling, C Chaguza, SJ Salter, P Hinfonthong, E Nikolaou, ... Nature Microbiology 7 (11), 1791-1804, 2022 | 43 | 2022 |
Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2 E Mitsi, J Reiné, BC Urban, C Solórzano, E Nikolaou, AD Hyder-Wright, ... The Journal of clinical investigation 132 (7), 2022 | 43 | 2022 |
Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine BF Carniel, F Marcon, J Rylance, EL German, S Zaidi, J Reiné, E Negera, ... JCI insight 6 (4), 2021 | 42 | 2021 |
Pneumococcal colonization in healthy adult research participants in the conjugate vaccine era, United Kingdom, 2010–2017 H Adler, E Nikolaou, K Gould, J Hinds, AM Collins, V Connor, C Hales, ... The Journal of infectious diseases 219 (12), 1989-1993, 2019 | 38 | 2019 |
Protective effect of PCV vaccine against experimental pneumococcal challenge in adults is primarily mediated by controlling colonisation density EL German, C Solórzano, S Sunny, F Dunne, JF Gritzfeld, E Mitsi, ... Vaccine 37 (30), 3953-3956, 2019 | 34 | 2019 |
Experimental human pneumococcal colonization in older adults is feasible and safe, not immunogenic H Adler, EL German, E Mitsi, E Nikolaou, S Pojar, C Hales, R Robinson, ... American journal of respiratory and critical care medicine 203 (5), 604-613, 2021 | 27 | 2021 |
Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study V Connor, E German, S Pojar, E Mitsi, C Hales, E Nikolaou, ... European Respiratory Journal 52 (4), 2018 | 22 | 2018 |
Experimental human challenge defines distinct pneumococcal kinetic profiles and mucosal responses between colonized and non-colonized adults E Nikolaou, SP Jochems, E Mitsi, S Pojar, A Blizard, J Reiné, C Solórzano, ... MBio 12 (1), 10.1128/mbio. 02020-20, 2021 | 19 | 2021 |
Association between household air pollution and nasopharyngeal pneumococcal carriage in Malawian infants (MSCAPE): a nested, prospective, observational study MK Dherani, D Pope, T Tafatatha, E Heinsbroek, R Chartier, ... The Lancet Global Health 10 (2), e246-e256, 2022 | 16 | 2022 |
Antibiotic Resistance Is Associated with Integrative and Conjugative Elements and Genomic Islands in Naturally Circulating Streptococcus pneumoniae Isolates … E Nikolaou, ATM Hubbard, J Botelho, TAM Marschall, DM Ferreira, ... Genes 11 (6), 625, 2020 | 11 | 2020 |
Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan J Reiné, BF Carniel, C Solórzano, E Mitsi, S Pojar, E Nikolaou, ... bioRxiv, 576744, 2019 | 10 | 2019 |