Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation J Swift, IL Ivanovska, A Buxboim, T Harada, PCDP Dingal, J Pinter, ... Science 341 (6149), 1240104, 2013 | 1975 | 2013 |
Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival T Harada, J Swift, J Irianto, JW Shin, KR Spinler, A Athirasala, ... Journal of Cell Biology 204 (5), 669-682, 2014 | 634 | 2014 |
Matrix elasticity regulates lamin-A, C phosphorylation and turnover with feedback to actomyosin A Buxboim, J Swift, J Irianto, KR Spinler, PCDP Dingal, A Athirasala, ... Current Biology 24 (16), 1909-1917, 2014 | 381 | 2014 |
Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain M Raab, J Swift, PCD P. Dingal, P Shah, JW Shin, DE Discher Journal of Cell Biology 199 (4), 669-683, 2012 | 330 | 2012 |
Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells JW Shin, A Buxboim, KR Spinler, J Swift, DA Christian, CA Hunter, C Léon, ... Cell stem cell 14 (1), 81-93, 2014 | 172 | 2014 |
Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor PCDP Dingal, AM Bradshaw, S Cho, M Raab, A Buxboim, J Swift, ... Nature materials 14 (9), 951-960, 2015 | 124 | 2015 |
SIRPA-inhibited, marrow-derived macrophages engorge, accumulate, and differentiate in antibody-targeted regression of solid tumors CM Alvey, KR Spinler, J Irianto, CR Pfeifer, B Hayes, Y Xia, S Cho, ... Current Biology 27 (14), 2065-2077. e6, 2017 | 123 | 2017 |
Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system NH Kipniss, PCDP Dingal, TR Abbott, Y Gao, H Wang, AA Dominguez, ... Nature communications 8 (1), 2212, 2017 | 102 | 2017 |
Combining insoluble and soluble factors to steer stem cell fate PCDP Dingal, DE Discher Nature materials 13 (6), 532-537, 2014 | 95 | 2014 |
Stress sensitivity and mechanotransduction during heart development S Majkut, PCDP Dingal, DE Discher Current Biology 24 (10), R495-R501, 2014 | 74 | 2014 |
Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation IL Ivanovska, J Swift, K Spinler, D Dingal, S Cho, DE Discher Molecular biology of the cell 28 (14), 2010-2022, 2017 | 69 | 2017 |
Systems mechanobiology: tension-inhibited protein turnover is sufficient to physically control gene circuits PCDP Dingal, DE Discher Biophysical journal 107 (11), 2734-2743, 2014 | 55 | 2014 |
Material control of stem cell differentiation: challenges in nano-characterization PCDP Dingal, DE Discher Current Opinion in Biotechnology 28, 46-50, 2014 | 45 | 2014 |
Chimeric proteins and methods of regulating gene expression LS Qi, PCDP Dingal US Patent 9,856,497, 2018 | 27 | 2018 |
Simple insoluble cues specify stem cell differentiation PCDP Dingal, RG Wells, DE Discher Proceedings of the National Academy of Sciences 111 (51), 18104-18105, 2014 | 11 | 2014 |
Manipulating the mechanics of extracellular matrix to study effects on the nucleus and its structure Y Xia, S Cho, M Vashisth, IL Ivanovska, PCDP Dingal, DE Discher Methods 157, 3-14, 2019 | 4 | 2019 |
Chimeric proteins and methods of regulating gene expression LS Qi, PCDP Dingal US Patent 10,457,961, 2019 | 3 | 2019 |
Regulation of Vg1 biogenesis during mesendoderm induction PCDP Dingal, AN Carte, TG Montague, AF Schier bioRxiv, 441333, 2021 | 2 | 2021 |
Chimeric proteins and methods of regulating gene expression LS Qi, PCDP Dingal US Patent App. 16/570,827, 2020 | 1 | 2020 |
Engineering Cell Sensing and Responses Using a GPCR-Coupled CRISPR-Cas System PCDP Dingal, NH Kipniss, L Labanieh, Y Gao, LS Qi bioRxiv, 152496, 2017 | 1 | 2017 |