A huntingtin knockin pig model recapitulates features of selective neurodegeneration in Huntington’s disease S Yan, Z Tu, Z Liu, N Fan, H Yang, S Yang, W Yang, Y Zhao, Z Ouyang, ... Cell 173 (4), 989-1002. e13, 2018 | 331 | 2018 |
Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer X Zhou, J Xin, N Fan, Q Zou, J Huang, Z Ouyang, Y Zhao, B Zhao, Z Liu, ... Cellular and molecular life sciences 72, 1175-1184, 2015 | 323 | 2015 |
Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs D Yang, CE Wang, B Zhao, W Li, Z Ouyang, Z Liu, H Yang, P Fan, ... Human molecular genetics 19 (20), 3983-3994, 2010 | 216 | 2010 |
Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning D Yang, H Yang, W Li, B Zhao, Z Ouyang, Z Liu, Y Zhao, N Fan, J Song, ... Cell research 21 (6), 979-982, 2011 | 213 | 2011 |
Generation of gene-target dogs using CRISPR/Cas9 system Q Zou, X Wang, Y Liu, Z Ouyang, H Long, S Wei, J Xin, B Zhao, S Lai, ... Journal of molecular cell biology 7 (6), 580-583, 2015 | 180 | 2015 |
Small molecules enhance CRISPR/Cas9-mediated homology-directed genome editing in primary cells G Li, X Zhang, C Zhong, J Mo, R Quan, J Yang, D Liu, Z Li, H Yang, Z Wu Scientific Reports 7 (1), 8943, 2017 | 164 | 2017 |
CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus H Yang, J Zhang, X Zhang, J Shi, Y Pan, R Zhou, G Li, Z Li, G Cai, Z Wu Antiviral research 151, 63-70, 2018 | 134 | 2018 |
Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs J Xin, H Yang, N Fan, B Zhao, Z Ouyang, Z Liu, Y Zhao, X Li, J Song, ... PloS one 8 (12), e84250, 2013 | 124 | 2013 |
RAG1/2 knockout pigs with severe combined immunodeficiency J Huang, X Guo, N Fan, J Song, B Zhao, Z Ouyang, Z Liu, Y Zhao, Q Yan, ... The Journal of Immunology 193 (3), 1496-1503, 2014 | 111 | 2014 |
Generation of multi-gene knockout rabbits using the Cas9/gRNA system Q Yan, Q Zhang, H Yang, Q Zou, C Tang, N Fan, L Lai Cell regeneration 3 (1), 3: 12, 2014 | 106 | 2014 |
Genome editing of pigs for agriculture and biomedicine H Yang, Z Wu Frontiers in Genetics 9, 360, 2018 | 99 | 2018 |
Generation of RAG 1-and 2-deficient rabbits by embryo microinjection of TALENs J Song, J Zhong, X Guo, Y Chen, Q Zou, J Huang, X Li, Q Zhang, Z Jiang, ... Cell research 23 (8), 1059-1062, 2013 | 91 | 2013 |
Exploring the fecal microbial composition and metagenomic functional capacities associated with feed efficiency in commercial DLY pigs J Quan, G Cai, M Yang, Z Zeng, R Ding, X Wang, Z Zhuang, S Zhou, S Li, ... Frontiers in microbiology 10, 52, 2019 | 66 | 2019 |
Species-dependent neuropathology in transgenic SOD1 pigs H Yang, G Wang, H Sun, R Shu, T Liu, CE Wang, Z Liu, Y Zhao, B Zhao, ... Cell research 24 (4), 464-481, 2014 | 66 | 2014 |
Novel transgenic pigs with enhanced growth and reduced environmental impact X Zhang, Z Li, H Yang, D Liu, G Cai, G Li, J Mo, D Wang, C Zhong, ... elife 7, e34286, 2018 | 65 | 2018 |
Suppressing Ku70/Ku80 expression elevates homology-directed repair efficiency in primary fibroblasts G Li, D Liu, X Zhang, R Quan, C Zhong, J Mo, Y Huang, H Wang, X Ruan, ... The international journal of biochemistry & cell biology 99, 154-160, 2018 | 57 | 2018 |
Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain G Wang, H Yang, S Yan, CE Wang, X Liu, B Zhao, Z Ouyang, P Yin, Z Liu, ... Molecular neurodegeneration 10, 1-20, 2015 | 54 | 2015 |
Genome-wide analysis of circular RNAs mediated ceRNA regulation in porcine embryonic muscle development L Hong, T Gu, Y He, C Zhou, Q Hu, X Wang, E Zheng, S Huang, Z Xu, ... Frontiers in cell and developmental biology 7, 289, 2019 | 45 | 2019 |
Multiple systemic transplantations of human amniotic mesenchymal stem cells exert therapeutic effects in an ALS mouse model H Sun, Z Hou, H Yang, M Meng, P Li, Q Zou, L Yang, Y Chen, H Chai, ... Cell and Tissue Research 357, 571-582, 2014 | 39 | 2014 |
Genome-wide association analysis reveals genetic loci and candidate genes for feeding behavior and eating efficiency in Duroc boars R Ding, J Quan, M Yang, X Wang, E Zheng, H Yang, D Fu, Y Yang, ... PLoS One 12 (8), e0183244, 2017 | 38 | 2017 |