Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes TA Graubert, D Shen, L Ding, T Okeyo-Owuor, CL Lunn, J Shao, K Krysiak, ... Nature genetics 44 (1), 53-57, 2012 | 654 | 2012 |
Mutant U2AF1 expression alters hematopoiesis and pre-mRNA splicing in vivo CL Shirai, JN Ley, BS White, S Kim, J Tibbitts, J Shao, M Ndonwi, ... Cancer cell 27 (5), 631-643, 2015 | 332 | 2015 |
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome CL Shirai, BS White, M Tripathi, R Tapia, JN Ley, M Ndonwi, S Kim, ... Nature communications 8 (1), 14060, 2017 | 128 | 2017 |
Activation of Cdk2/Cyclin E complexes is dependent on the origin of replication licensing factor Cdc6 in mammalian cells CL Lunn, JC Chrivia, JJ Baldassare Cell Cycle 9 (22), 4533-4541, 2010 | 41 | 2010 |
Resolution of secondary hemophagocytic lymphohistiocytosis after treatment with the JAK1/2 inhibitor ruxolitinib SR Goldsmith, SSU Rehman, CL Shirai, K Vij, JF DiPersio Blood Advances 3 (23), 4131-4135, 2019 | 39 | 2019 |
Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells T Liu, K Krysiak, CL Shirai, S Kim, J Shao, M Ndonwi, MJ Walter PLoS One 12 (2), e0170470, 2017 | 34 | 2017 |
Sequencing-based measurable residual disease testing in acute myeloid leukemia JM Yoest, CL Shirai, EJ Duncavage Frontiers in Cell and Developmental Biology 8, 249, 2020 | 31 | 2020 |
Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice SP Kim, SN Srivatsan, M Chavez, CL Shirai, BS White, T Ahmed, ... Cell reports 36 (9), 2021 | 16 | 2021 |
Preclinical activity of splicing modulators in U2AF1 mutant MDS/AML CL Shirai, M Tripathi, JN Ley, M Ndonwi, BS White, R Tapia, B Saez, ... Blood 126 (23), 1653, 2015 | 13 | 2015 |
U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice BA Wadugu, SN Srivatsan, A Heard, MO Alberti, M Ndonwi, J Liu, S Grieb, ... The Journal of Clinical Investigation 131 (21), 2021 | 11 | 2021 |
Technological features of blast identification in the cerebrospinal fluid: a systematic review of flow cytometry and laboratory haematology methods JL Frater, CL Shirai, JR Brestoff International journal of laboratory hematology 44, 45-53, 2022 | 6 | 2022 |
Haploinsufficiency of multiple del (5q) genes induce B cell abnormalities in mice T Liu, T Ahmed, K Krysiak, CL Shirai, J Shao, R Nunley, R Bucala, ... Leukemia research 96, 106428, 2020 | 6 | 2020 |
Mutant U2AF1S34F and U2AF1Q157P induce distinct RNA splicing and hematopoietic phenotypes in vivo MO Alberti, SN Srivatsan, T Ahmed, JJ Shao, B Wadugu, CL Shirai, ... Blood 134, 770, 2019 | 4 | 2019 |
Mutant U2AF1 expression alters hematopoiesis and Pre-mRNA splicing in transgenic mice CL Shirai, JN Ley, BS White, J Tibbitts, J Shao, M Ndonwi, S Kim, ... Blood 124 (21), 827, 2014 | 4 | 2014 |
Sudemycin selectively inhibits growth of primary murine hematopoietic cells expressing mutant U2AF1 M Tripathi, CL Lunn, T Okeyo-Owuor, MJ Walter, TR Webb, T Graubert Blood 120 (21), 554, 2012 | 3 | 2012 |
Evaluation of Breast Implant–Associated Anaplastic Large Cell Lymphoma With Whole Exome and Genome Sequencing N Akkad, R Kodgule, EJ Duncavage, N Mehta-Shah, DH Spencer, ... Aesthetic surgery journal 43 (3), 318-328, 2023 | 2 | 2023 |
U2AF1 is a haplo-essential gene required for cancer cell survival BA Wadugu, A Heard, SN Srivatsan, MO Alberti, M Ndonwi, S Grieb, ... bioRxiv, 2020.06. 20.151035, 2020 | 2 | 2020 |
Dramatic Resolution of HLH after Treatment with the JAK 1/2 Inhibitor, Ruxolitinib SR Goldsmith, SSU Rehman, CL Shirai, R Vij, JF DiPersio Blood 134, 2325, 2019 | 1 | 2019 |
Serendipity: decitabine monotherapy induced complete molecular response in a 77-year-old patient with acute promyelocytic leukemia R Abboud, SY Han, EJ Duncavage, AF Cashen, CL Shirai, JS Welch, ... haematologica 104 (4), e170, 2019 | 1 | 2019 |
Knockdown of HSPA9 induces apoptosis and increases TP53 levels in human CD34+ hematopoietic progenitor cells T Liu, K Krysiak, CL Shirai, M Ndonwi, MJ Walter Blood 124 (21), 526, 2014 | 1 | 2014 |