In silico toxicology protocols GJ Myatt, E Ahlberg, Y Akahori, D Allen, A Amberg, LT Anger, A Aptula, ... Regulatory Toxicology and Pharmacology 96, 1-17, 2018 | 221 | 2018 |
Genetic toxicology in silico protocol C Hasselgren, E Ahlberg, Y Akahori, A Amberg, LT Anger, F Atienzar, ... Regulatory Toxicology and Pharmacology 107, 104403, 2019 | 71 | 2019 |
Skin sensitization in silico protocol C Johnson, E Ahlberg, LT Anger, L Beilke, R Benigni, J Bercu, S Bobst, ... Regulatory Toxicology and Pharmacology 116, 104688, 2020 | 43 | 2020 |
Controlled formation of an axially bonded Co-phthalocyanine dimer X Ge, C Manzano, R Berndt, LT Anger, F Köhler, R Herges Journal of the American Chemical Society 131 (17), 6096-6098, 2009 | 37 | 2009 |
A physiologically based toxicokinetic modelling approach to predict relevant concentrations for in vitro testing H Mielke, LT Anger, M Schug, JG Hengstler, R Stahlmann, ... Archives of toxicology 85, 555-563, 2011 | 35 | 2011 |
Development of in silico filters to predict activation of the pregnane X receptor (PXR) by structurally diverse drug-like molecules H Matter, LT Anger, C Giegerich, S Güssregen, G Hessler, KH Baringhaus Bioorganic & medicinal chemistry 20 (18), 5352-5365, 2012 | 33 | 2012 |
In silico approaches in organ toxicity hazard assessment: current status and future needs in predicting liver toxicity A Bassan, VM Alves, A Amberg, LT Anger, S Auerbach, L Beilke, ... Computational Toxicology 20, 100187, 2021 | 30 | 2021 |
In silico approaches in carcinogenicity hazard assessment: current status and future needs RR Tice, A Bassan, A Amberg, LT Anger, MA Beal, P Bellion, R Benigni, ... Computational Toxicology 20, 100191, 2021 | 28 | 2021 |
In silico approaches in organ toxicity hazard assessment: Current status and future needs for predicting heart, kidney and lung toxicities A Bassan, VM Alves, A Amberg, LT Anger, L Beilke, A Bender, A Bernal, ... Computational Toxicology 20, 100188, 2021 | 26 | 2021 |
Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q) SAR analyses A Amberg, RV Andaya, LT Anger, C Barber, L Beilke, J Bercu, D Bower, ... Regulatory toxicology and pharmacology 102, 53-64, 2019 | 24 | 2019 |
Evaluating confidence in toxicity assessments based on experimental data and in silico predictions C Johnson, LT Anger, R Benigni, D Bower, F Bringezu, KM Crofton, ... Computational Toxicology 21, 100204, 2022 | 18 | 2022 |
Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: is aromatic N-oxide a structural alert for predicting DNA-reactive mutagenicity? A Amberg, LT Anger, J Bercu, D Bower, KP Cross, L Custer, JS Harvey, ... Mutagenesis 34 (1), 67-82, 2019 | 16 | 2019 |
Principles and procedures for assessment of acute toxicity incorporating in silico methods CM Zwickl, JC Graham, RA Jolly, A Bassan, E Ahlberg, A Amberg, ... Computational Toxicology 24, 100237, 2022 | 13 | 2022 |
Toward implementing virtual control groups in nonclinical safety studies: Workshop report and roadmap to implementation E Golden, D Allen, A Amberg, LT Anger, E Baker, SW Baran, F Bringezu, ... | 10 | 2023 |
Generalized workflow for generating highly predictive in silico off-target activity models LT Anger, A Wolf, KJ Schleifer, D Schrenk, SG Rohrer Journal of Chemical Information and Modeling 54 (9), 2411-2422, 2014 | 8 | 2014 |
Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines C Kamper, K Korpis, E Specker, L Anger, M Neuenschwander, ... Molecular diversity 16, 541-551, 2012 | 8 | 2012 |
Points to consider regarding the use and implementation of virtual controls in nonclinical general toxicology studies X Palazzi, LT Anger, T Boulineau, A Grevot, M Guffroy, K Henson, ... Regulatory Toxicology and Pharmacology 150, 105632, 2024 | 7 | 2024 |
Generating modeling data from repeat-dose toxicity reports O López-Massaguer, K Pinto-Gil, F Sanz, A Amberg, LT Anger, M Stolte, ... Toxicological Sciences 162 (1), 287-300, 2018 | 5 | 2018 |
Toward Quantitative Models in Safety Assessment: A Case Study to Show Impact of Dose–Response Inference on hERG Inhibition Models F Melnikov, LT Anger, C Hasselgren International Journal of Molecular Sciences 24 (1), 635, 2022 | 4 | 2022 |
The application of acute oral toxicity computational models in dangerous goods classification C Moudgal, LT Anger, W Muster, R Nguyen, F Melnikov, VB Siramshetty, ... Toxicology and Industrial Health 39 (12), 687-699, 2023 | 2 | 2023 |