| A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth S Bonnet, SL Archer, J Allalunis-Turner, A Haromy, C Beaulieu, ... Cancer cell 11 (1), 37-51, 2007 | 1957 | 2007 |
| Metabolic modulation of glioblastoma with dichloroacetate ED Michelakis, G Sutendra, P Dromparis, L Webster, A Haromy, E Niven, ... Science translational medicine 2 (31), 31ra34-31ra34, 2010 | 897 | 2010 |
| An abnormal mitochondrial–hypoxia inducible factor-1α–Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities … S Bonnet, ED Michelakis, CJ Porter, MA Andrade-Navarro, B Thébaud, ... Circulation 113 (22), 2630-2641, 2006 | 671 | 2006 |
| Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility J Nagendran, SL Archer, D Soliman, V Gurtu, R Moudgil, A Haromy, ... Circulation 116 (3), 238-248, 2007 | 619 | 2007 |
| Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis MS McMurtry, S Bonnet, X Wu, JRB Dyck, A Haromy, K Hashimoto, ... Circulation research 95 (8), 830-840, 2004 | 571 | 2004 |
| Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that … B Thébaud, F Ladha, ED Michelakis, M Sawicka, G Thurston, F Eaton, ... Circulation 112 (16), 2477-2486, 2005 | 568 | 2005 |
| A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation G Sutendra, A Kinnaird, P Dromparis, R Paulin, TH Stenson, A Haromy, ... Cell 158 (1), 84-97, 2014 | 561 | 2014 |
| Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats T van Haaften, R Byrne, S Bonnet, GY Rochefort, J Akabutu, ... American journal of respiratory and critical care medicine 180 (11), 1131-1142, 2009 | 500 | 2009 |
| Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension MS McMurtry, SL Archer, DC Altieri, S Bonnet, A Haromy, G Harry, ... The Journal of clinical investigation 115 (6), 1479-1491, 2005 | 477 | 2005 |
| The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted S Bonnet, G Rochefort, G Sutendra, SL Archer, A Haromy, L Webster, ... Proceedings of the National Academy of Sciences 104 (27), 11418-11423, 2007 | 446 | 2007 |
| Phosphatidylethanolamine deficiency in Mammalian mitochondria impairs oxidative phosphorylation and alters mitochondrial morphology G Tasseva, HD Bai, M Davidescu, A Haromy, E Michelakis, JE Vance Journal of Biological Chemistry 288 (6), 4158-4173, 2013 | 342 | 2013 |
| Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension G Sutendra, S Bonnet, G Rochefort, A Haromy, KD Folmes, ... Science translational medicine 2 (44), 44ra58-44ra58, 2010 | 263 | 2010 |
| The role of Nogo and the mitochondria–endoplasmic reticulum unit in pulmonary hypertension G Sutendra, P Dromparis, P Wright, S Bonnet, A Haromy, Z Hao, ... Science translational medicine 3 (88), 88ra55-88ra55, 2011 | 240 | 2011 |
| A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary … G Sutendra, P Dromparis, R Paulin, S Zervopoulos, A Haromy, ... Journal of molecular medicine 91, 1315-1327, 2013 | 237 | 2013 |
| Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer G Sutendra, P Dromparis, A Kinnaird, TH Stenson, A Haromy, JMR Parker, ... Oncogene 32 (13), 1638-1650, 2013 | 231 | 2013 |
| Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans R Paulin, P Dromparis, G Sutendra, V Gurtu, S Zervopoulos, L Bowers, ... Cell metabolism 20 (5), 827-839, 2014 | 228 | 2014 |
| Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen … H Kajimoto, K Hashimoto, SN Bonnet, A Haromy, G Harry, R Moudgil, ... Circulation 115 (13), 1777-1788, 2007 | 185 | 2007 |
| Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension P Dromparis, R Paulin, TH Stenson, A Haromy, G Sutendra, ... Circulation 127 (1), 115-125, 2013 | 174 | 2013 |
| Dehydroepiandrosterone reverses systemic vascular remodeling through the inhibition of the Akt/GSK3-β/NFAT axis S Bonnet, R Paulin, G Sutendra, P Dromparis, M Roy, KO Watson, ... Circulation 120 (13), 1231-1240, 2009 | 153 | 2009 |
| A miR-208–Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension R Paulin, G Sutendra, V Gurtu, P Dromparis, A Haromy, S Provencher, ... Circulation research 116 (1), 56-69, 2015 | 138 | 2015 |
