| Resolving the fibrotic niche of human liver cirrhosis at single-cell level P Ramachandran, R Dobie, JR Wilson-Kanamori, EF Dora, ... Nature 575 (7783), 512-518, 2019 | 1106 | 2019 |
| Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis R Dobie, JR Wilson-Kanamori, BEP Henderson, JR Smith, KP Matchett, ... Cell reports 29 (7), 1832-1847. e8, 2019 | 313 | 2019 |
| Management of liver trauma SA Badger, R Barclay, P Campbell, DJ Mole, T Diamond World journal of surgery 33, 2522-2537, 2009 | 211 | 2009 |
| Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell–IL-22 axis R Duffin, RA O’Connor, S Crittenden, T Forster, C Yu, X Zheng, D Smyth, ... Science 351 (6279), 1333-1338, 2016 | 173 | 2016 |
| Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis DJ Mole, SP Webster, I Uings, X Zheng, M Binnie, K Wilson, ... Nature medicine 22 (2), 202-209, 2016 | 144 | 2016 |
| Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records DJ Mole, B Olabi, V Robinson, OJ Garden, RW Parks Hpb 11 (2), 166-170, 2009 | 134 | 2009 |
| Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo JA Fallowfield, AL Hayden, VK Snowdon, RL Aucott, BM Stutchfield, ... Hepatology 59 (4), 1492-1504, 2014 | 109 | 2014 |
| The intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitis JE Fishman, G Levy, V Alli, X Zheng, DJ Mole, EA Deitch Shock 42 (3), 264-270, 2014 | 91 | 2014 |
| Detailed fluid resuscitation profiles in patients with severe acute pancreatitis DJ Mole, A Hall, D McKeown, OJ Garden, RW Parks Hpb 13 (1), 51-58, 2011 | 71 | 2011 |
| Stromal cells covering omental fat-associated lymphoid clusters trigger formation of neutrophil aggregates to capture peritoneal contaminants LH Jackson-Jones, P Smith, JR Portman, MS Magalhaes, KJ Mylonas, ... Immunity 52 (4), 700-715. e6, 2020 | 70 | 2020 |
| ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: a rationale for safer glucocorticoid replacement therapy M Nixon, SD Mackenzie, AI Taylor, NZM Homer, DE Livingstone, ... Science Translational Medicine 8 (352), 352ra109-352ra109, 2016 | 64 | 2016 |
| Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the … CM Bunce, JC Mountford, PJ French, DJ Mole, J Durham, RH Michell, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1311 (3), 189-198, 1996 | 53 | 1996 |
| Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct RH Stimson, AJ Anderson, LE Ramage, DP Macfarlane, AC de Beaux, ... Diabetes, Obesity and Metabolism 19 (6), 883-891, 2017 | 52 | 2017 |
| Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells S Crittenden, M Goepp, J Pollock, CT Robb, DJ Smyth, Y Zhou, ... Science advances 7 (7), eabd7954, 2021 | 50 | 2021 |
| Pre-, peri-and post-operative factors for the development of pancreatic fistula after pancreatic surgery K Søreide, AJ Healey, DJ Mole, RW Parks Hpb 21 (12), 1621-1631, 2019 | 50 | 2019 |
| Tryptophan catabolites in mesenteric lymph may contribute to pancreatitis-associated organ failure DJ Mole, NV McFerran, G Collett, C O'Neill, T Diamond, OJ Garden, ... Journal of British Surgery 95 (7), 855-867, 2008 | 48 | 2008 |
| Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury X Zheng, A Zhang, M Binnie, K McGuire, SP Webster, J Hughes, ... Experimental & Molecular Medicine 51 (2), 1-14, 2019 | 47 | 2019 |
| Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase JP Hutchinson, P Rowland, MRD Taylor, EM Christodoulou, C Haslam, ... Nature Communications 8 (1), 15827, 2017 | 44 | 2017 |
| Lead discovery for human kynurenine 3-monooxygenase by high-throughput RapidFire mass spectrometry DM Lowe, M Gee, C Haslam, B Leavens, E Christodoulou, P Hissey, ... Journal of biomolecular screening 19 (4), 508-515, 2014 | 44 | 2014 |
| The isolated perfused liver response to a ‘second hit’of portal endotoxin during severe acute pancreatitis DJ Mole, MA Taylor, NV McFerran, T Diamond Pancreatology 5 (4-5), 475-485, 2005 | 41 | 2005 |
