Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration A Raven, WY Lu, TY Man, S Ferreira-Gonzalez, E O’Duibhir, BJ Dwyer, ... Nature 547 (7663), 350-354, 2017 | 506 | 2017 |
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence TG Bird, M Müller, L Boulter, DF Vincent, RA Ridgway, ... Science translational medicine 10 (454), eaan1230, 2018 | 214 | 2018 |
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration S Ferreira-Gonzalez, WY Lu, A Raven, B Dwyer, TY Man, E O’Duibhir, ... Nature Communications 9 (1), 1020, 2018 | 139 | 2018 |
Interleukin-13 activates distinct cellular pathways leading to ductular reaction, steatosis, and fibrosis RL Gieseck, TR Ramalingam, KM Hart, KM Vannella, DA Cantu, WY Lu, ... Immunity 45 (1), 145-158, 2016 | 130 | 2016 |
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair KJ Mylonas, ED O’Sullivan, D Humphries, DP Baird, MH Docherty, ... Science translational medicine 13 (594), eabb0203, 2021 | 105 | 2021 |
The STAT3–IL-10–IL-6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury L Campana, PJ Starkey Lewis, A Pellicoro, RL Aucott, J Man, E O’Duibhir, ... The Journal of Immunology 200 (3), 1169-1187, 2018 | 95 | 2018 |
Notch3 drives development and progression of cholangiocarcinoma RV Guest, L Boulter, BJ Dwyer, TJ Kendall, TY Man, SE Minnis-Lyons, ... Proceedings of the National Academy of Sciences 113 (43), 12250-12255, 2016 | 94 | 2016 |
Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis M Reich, L Spomer, C Klindt, K Fuchs, J Stindt, K Deutschmann, J Höhne, ... Journal of hepatology 75 (3), 634-646, 2021 | 72 | 2021 |
TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression BJ Dwyer, EJ Jarman, J Gogoi-Tiwari, S Ferreira-Gonzalez, L Boulter, ... Journal of hepatology 74 (4), 860-872, 2021 | 65 | 2021 |
Combination of G-CSF and a TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of ACLF C Engelmann, A Habtesion, M Hassan, AJC Kerbert, L Hammerich, ... Journal of hepatology 77 (5), 1325-1338, 2022 | 46 | 2022 |
Cellular senescence in liver disease and regeneration S Ferreira-Gonzalez, D Rodrigo-Torres, VL Gadd, SJ Forbes Seminars in liver disease 41 (01), 050-066, 2021 | 38 | 2021 |
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease JM Hallett, S Ferreira-Gonzalez, TY Man, AM Kilpatrick, H Esser, ... Cell stem cell 29 (3), 355-371. e10, 2022 | 34 | 2022 |
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation SE Minnis-Lyons, S Ferreira-González, N Aleksieva, TY Man, VL Gadd, ... Science Signaling 14 (688), eaay9185, 2021 | 29 | 2021 |
Fibroblast growth factor 7 releasing particles enhance islet engraftment and improve metabolic control following islet transplantation in mice with diabetes SM Alwahsh, O Qutachi, PJS Lewis, A Bond, J Noble, P Burgoyne, ... American Journal of Transplantation 21 (9), 2950-2963, 2021 | 16 | 2021 |
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage S Ferreira-Gonzalez, TY Man, H Esser, R Aird, AM Kilpatrick, ... Science Translational Medicine 14 (674), eabj4375, 2022 | 15 | 2022 |
Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure J Meseguer-Ripolles, B Lucendo-Villarin, C Tucker, S Ferreira-Gonzalez, ... Iscience 24 (6), 2021 | 10 | 2021 |
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Sci Transl Med. 2018; 10: eaan1230 TG Bird, M Müller, L Boulter, DF Vincent, RA Ridgway, ... | 10 | |
Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice J Chen, NC Cheng, JA Boland, K Liu, JG Kench, DN Watkins, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (4), 166335, 2022 | 7 | 2022 |
Correction: Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration A Raven, WY Lu, TY Man, S Ferreira-Gonzalez, E O’Duibhir, BJ Dwyer, ... Nature 555 (7696), 402-402, 2018 | 5 | 2018 |
Toll-like receptor 4 inhibition acts synergistically with G-CSF to prevent organ injury and induce liver regeneration in acute-on-chronic liver failure C Engelmann, F Andreola, A Habtesion, S Novelli, A Kerbert, N Davies, ... Journal of Hepatology 73, S28, 2020 | 2 | 2020 |