Structure of the first parallel DNA quadruplex-drug complex GR Clark, PD Pytel, CJ Squire, S Neidle Journal of the American Chemical Society 125 (14), 4066-4067, 2003 | 285 | 2003 |
Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis N Koon, CJ Squire, EN Baker Proceedings of the National Academy of Sciences 101 (22), 8295-8300, 2004 | 156 | 2004 |
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed Y Yosaatmadja, S Silva, JM Dickson, AV Patterson, JB Smaill, ... Journal of structural biology 192 (3), 539-544, 2015 | 135 | 2015 |
Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypicaltyrosine kinase with a key role in CDK1 regulation CJ Squire, JM Dickson, I Ivanovic, EN Baker Structure 13 (4), 541-550, 2005 | 129 | 2005 |
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of … G Bashiri, CJ Squire, NJ Moreland, EN Baker Journal of Biological Chemistry 283 (25), 17531-17541, 2008 | 112 | 2008 |
Trapping HIV-1 reverse transcriptase before and after translocation on DNA SG Sarafianos, AD Clark, S Tuske, CJ Squire, K Das, D Sheng, ... Journal of Biological Chemistry 278 (18), 16280-16288, 2003 | 106 | 2003 |
TAS‐120 cancer target binding: defining reactivity and revealing the first fibroblast growth factor receptor 1 (FGFR1) irreversible structure M Kalyukina, Y Yosaatmadja, MJ Middleditch, AV Patterson, JB Smaill, ... ChemMedChem 14 (4), 494-500, 2019 | 102 | 2019 |
Structure and function of GlmU from Mycobacterium tuberculosis Z Zhang, EMM Bulloch, RD Bunker, EN Baker, CJ Squire Acta Crystallographica Section D: Biological Crystallography 65 (3), 275-283, 2009 | 88 | 2009 |
Designer DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d (CGCGAATTCGCG) 2 GR Clark, CJ Squire, EJ Gray, W Leupin, S Neidle Nucleic acids research 24 (24), 4882-4889, 1996 | 74 | 1996 |
High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon, NR Ileperuma, SDG Marshall, CJ Squire, HM Baker, JG Oakeshott, ... Biochemistry 46 (7), 1851-1859, 2007 | 73 | 2007 |
In vitro studies with methylproamine: a potent new radioprotector RF Martin, S Broadhurst, ME Reum, CJ Squire, GR Clark, ... Cancer research 64 (3), 1067-1070, 2004 | 72 | 2004 |
MCR-1: a promising target for structure-based design of inhibitors to tackle polymyxin resistance SJ Son, R Huang, CJ Squire, IKH Leung Drug Discovery Today 24 (1), 206-216, 2019 | 70 | 2019 |
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3 JU Flanagan, Y Yosaatmadja, RM Teague, MZL Chai, AP Turnbull, ... Public Library of Science 7 (8), e43965, 2012 | 69 | 2012 |
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system G Bashiri, CJ Squire, EN Baker, NJ Moreland Protein expression and purification 54 (1), 38-44, 2007 | 64 | 2007 |
Radiation damage and racemic protein crystallography reveal the unique structure of the GASA/snakin protein superfamily H Yeung, CJ Squire, Y Yosaatmadja, S Panjikar, G López, A Molina, ... Angewandte Chemie 128 (28), 8062-8065, 2016 | 59 | 2016 |
Poxviral ankyrin proteins MH Herbert, CJ Squire, AA Mercer Viruses 7 (2), 709-738, 2015 | 59 | 2015 |
Defining the potassium binding region in an apple terpene synthase S Green, CJ Squire, NJ Nieuwenhuizen, EN Baker, W Laing Journal of Biological Chemistry 284 (13), 8661-8669, 2009 | 52 | 2009 |
Structure of Escherichia coli UDP-N-acetylmuramoyl: L-alanine ligase (MurC) T Deva, EN Baker, CJ Squire, CA Smith Acta Crystallographica Section D: Biological Crystallography 62 (12), 1466-1474, 2006 | 48 | 2006 |
Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin H Kwon, CJ Squire, PG Young, EN Baker Proceedings of the National Academy of Sciences 111 (4), 1367-1372, 2014 | 47 | 2014 |
The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages GR Clark, PD Pytel, CJ Squire Nucleic acids research 40 (12), 5731-5738, 2012 | 44 | 2012 |