The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals R LaRue, S Jónsson, K Silverstein, M Lajoie, D Bertrand, N El-Mabrouk, ... BMC molecular biology 9 (1), 104, 2008 | 221 | 2008 |
Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity L Kazak, JF Rahbani, B Samborska, GZ Lu, MP Jedrychowski, M Lajoie, ... Nature Metabolism, 1, 2019 | 133 | 2019 |
Spatially mapping the immune landscape of melanoma using imaging mass cytometry D Moldoveanu, LA Ramsay, M Lajoie, L Anderson-Trocme, M Lingrand, ... Science Immunology 7 (70), eabi5072, 2022 | 77 | 2022 |
Dual MAPK inhibition is an effective therapeutic strategy for a subset of class II BRAF mutant melanoma M Dankner, M Lajoie, D Moldoveanu, TT Nguyen, P Savage, S Rajkumar, ... Clinical Cancer Research, clincanres. 3384.2017, 2018 | 69 | 2018 |
Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment TT Nguyen, LA Ramsay, M Ahanfeshar-Adams, M Lajoie, D Schadendorf, ... Clinical Cancer Research, 2021 | 53 | 2021 |
A childhood acute lymphoblastic leukemia-specific lncRNA implicated in prednisolone resistance, cell proliferation, and migration M Ouimet, S Drouin, M Lajoie, M Caron, P St-Onge, R Gioia, C Richer, ... Oncotarget 8 (5), 7477, 2017 | 51 | 2017 |
Galvestine-1, a novel chemical probe for the study of the glycerolipid homeostasis system in plant cells L Boudière, CY Botté, N Saidani, M Lajoie, J Marion, L Bréhélin, ... Molecular BioSystems 8 (8), 2023-2035, 2012 | 44 | 2012 |
Characterization of the microDNA through the response to chemotherapeutics in lymphoblastoid cell lines P Mehanna, V Gagné, M Lajoie, JF Spinella, P St-Onge, D Sinnett, ... PloS one 12 (9), e0184365, 2017 | 42 | 2017 |
Duplication and inversion history of a tandemly repeated genes family M Lajoie, D Bertrand, N El-Mabrouk, O Gascuel Journal of Computational Biology 14 (4), 462-478, 2007 | 39 | 2007 |
Dynamic neutrophil-to-lymphocyte ratio: a novel prognosis measure for triple-negative breast cancer D Moldoveanu, V Pravongviengkham, G Best, C Martínez, T Hijal, ... Annals of Surgical Oncology 27 (10), 4028-4034, 2020 | 38 | 2020 |
Multi-omic analysis reveals significantly mutated genes and DDX3X as a sex-specific tumor suppressor in cutaneous melanoma R Alkallas, M Lajoie, D Moldoveanu, KV Hoang, P Lefrançois, M Lingrand, ... Nature Cancer 1 (6), 635-652, 2020 | 37 | 2020 |
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability KR Gillinder, MD Ilsley, D Nébor, R Sachidanandam, M Lajoie, GW Magor, ... Nucleic Acids Research, gkw1014, 2016 | 36 | 2016 |
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia B Neveu, JF Spinella, C Richer, P Cassart, M Lajoie, S Jananji, S Drouin, ... Haematologica, haematol. 2016.149740, 2016 | 33 | 2016 |
Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemia M Lajoie, S Drouin, M Caron, P St-Onge, M Ouimet, R Gioia, M Lafond, ... PLoS ONE 12 (3), 2017 | 27 | 2017 |
Inferring ancestral gene orders for a family of tandemly arrayed genes D Bertrand, M Lajoie, N El-Mabrouk Journal of Computational Biology 15 (8), 1063-1077, 2008 | 22 | 2008 |
p66ShcA functions as a contextual promoter of breast cancer metastasis K Lewis, A Kiepas, J Hudson, J Senecal, JR Ha, E Voorand, MG Annis, ... Breast Cancer Research 22 (1), 1-19, 2020 | 21 | 2020 |
Inferring the evolutionary history of gene clusters from phylogenetic and gene order data M Lajoie, D Bertrand, N El-Mabrouk Molecular biology and evolution 27 (4), 761-772, 2010 | 20 | 2010 |
Melanomas with concurrent BRAF non-p. V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy S Rajkumar, D Berry, KA Heney, C Strong, LA Ramsay, M Lajoie, ... Cell Reports 39 (1), 110634, 2022 | 19 | 2022 |
Computational discovery of regulatory elements in a continuous expression space M Lajoie, O Gascuel, V Lefort, L Bréhélin Genome biology 13 (11), R109, 2012 | 17 | 2012 |
Recurrent somatic BRAF insertion (p. V504_R506dup): a tumor marker and a potential therapeutic target in pilocytic astrocytoma F Khater, S Langlois, P Cassart, AM Roy, M Lajoie, J Healy, C Richer, ... Oncogene, 1, 2018 | 15 | 2018 |