PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA proficient triple negative breast cancer to PARP inhibition YH Ibrahim, C García-García, V Serra, L He, K Torres-Lockhart, A Prat, ... Cancer Discovery, 2012 | 594 | 2012 |
TBCRC009: a multicenter phase II clinical trial of platinum monotherapy with biomarker assessment in metastatic triple-negative breast cancer SJ Isakoff, EL Mayer, L He, TA Traina, LA Carey, KJ Krag, HS Rugo, ... Journal of clinical oncology 33 (17), 1902-1909, 2015 | 470 | 2015 |
Analysis and update of the human solute carrier (SLC) gene superfamily L He, K Vasiliou, DW Nebert Hum Genomics 3 (2), 195-206, 2009 | 420 | 2009 |
ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties L He, K Girijashanker, TP Dalton, J Reed, H Li, M Soleimani, DW Nebert Molecular pharmacology 70 (1), 171-180, 2006 | 383 | 2006 |
Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter K Girijashanker, L He, M Soleimani, JM Reed, H Li, Z Liu, B Wang, ... Molecular pharmacology 73 (5), 1413-1423, 2008 | 382 | 2008 |
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis TP Dalton, L He, B Wang, ML Miller, L Jin, KF Stringer, X Chang, ... Proceedings of the National Academy of Sciences 102 (9), 3401-3406, 2005 | 332 | 2005 |
Cd2+ versus Zn2+ uptake by the ZIP8 HCO3--dependent symporter: kinetics, electrogenicity and trafficking Z Liu, H Li, M Soleimani, K Girijashanker, JM Reed, L He, TP Dalton, ... Biochemical and biophysical research communications 365 (4), 814-820, 2008 | 191 | 2008 |
Discovery of ZIP transporters that participate in cadmium damage to testis and kidney L He, B Wang, EB Hay, DW Nebert Toxicology and applied pharmacology 238 (3), 250-257, 2009 | 146 | 2009 |
Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line B Wang, SN Schneider, N Dragin, K Girijashanker, TP Dalton, L He, ... American Journal of Physiology-Cell Physiology 292 (4), C1523-C1535, 2007 | 132 | 2007 |
Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma MR Ramsey, L He, N Forster, B Ory, LW Ellisen Cancer research 71 (13), 4373-4379, 2011 | 116 | 2011 |
ZIP8 Zinc Transporter: Indispensable Role for Both Multiple-Organ Organogenesis and Hematopoiesis In Utero M Gálvez-Peralta, L He, LF Jorge-Nebert, B Wang, ML Miller, BL Eppert, ... PloS one 7 (5), e36055, 2012 | 108 | 2012 |
PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition. Cancer Discov. 2012; 2: 1036–1047. doi: 10.1158/2159 … YH Ibrahim, C García-García, V Serra, L He, K Torres-Lockhart, A Prat, ... vitro/in vivo, 2013 | 99 | 2013 |
Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma L He, K Torres-Lockhart, N Forster, S Ramakrishnan, P Greninger, ... Cancer Discovery, 2012 | 76 | 2012 |
Safety and tolerability of veliparib combined with capecitabine plus radiotherapy in patients with locally advanced rectal cancer: a phase 1b study. MM Czito BG, Deming DA, Jameson GS, Mulcahy MF, Vaghefi H, Dudley MW, Holen ... Lancet Gastroenterol Hepatol., 2017 | 67 | 2017 |
ZIP14 and ZIP8 zinc/bicarbonate symporters in Xenopus oocytes: characterization of metal uptake and inhibition DW Nebert, M Gálvez-Peralta, EB Hay, H Li, E Johansson, C Yin, B Wang, ... Metallomics, 2012 | 65 | 2012 |
A role for BRCA1 in uterine leiomyosarcoma D Xing, G Scangas, M Nitta, L He, X Xu, YJM Ioffe, PJ Aspuria, CY Hedvat, ... Cancer research 69 (21), 8231-8235, 2009 | 63 | 2009 |
BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma N Ibrahim, L He, CO Leong, D Xing, BY Karlan, EM Swisher, BR Rueda, ... Cancer research 70 (18), 7155-7165, 2010 | 53 | 2010 |
Veliparib in combination with carboplatin and etoposide in patients with treatment-naïve extensive-stage small cell lung cancer: a phase 2 randomized study LA Byers, D Bentsion, S Gans, K Penkov, CH Son, A Sibille, ... Clinical Cancer Research 27 (14), 3884-3895, 2021 | 49 | 2021 |
Generation of a Slc39a8 hypomorph mouse: Markedly decreased ZIP8 Zn 2+/transporter expression B Wang, L He, H Dong, TP Dalton, DW Nebert Biochemical and Biophysical Research Communications 410 (2), 289-294, 2011 | 49 | 2011 |
A phase I dose-escalation study of veliparib combined with carboplatin and etoposide in patients with extensive-stage small cell lung cancer and other solid tumors F Atrafi, HJM Groen, LA Byers, E Garralda, MP Lolkema, RS Sangha, ... Clinical Cancer Research 25 (2), 496-505, 2019 | 42 | 2019 |